Results 191 to 200 of about 70,292 (240)

Topographical Variation of Iron‐Rimmed Lesions in the Multiple Sclerosis Brain and Spinal Cord: A Neuropathological Study

Annals of Neurology, Volume 99, Issue 3, Page 730-736, March 2026.
Paramagnetic‐rim lesions are a novel diagnostic marker in multiple sclerosis (MS) and are associated with poor prognosis due to their link with chronic inflammation and disease progression. Analyzing 46 postmortem MS cases, researchers found no iron rims in 67 white matter and 85 grey matter spinal cord lesions, despite most being active.
Marco Pisa, Andrew Lockhart, Thomas Angell, Aimee Avery, Zaenab Dhari, Mary Bailey, Simon Hametner, Hal Drakesmith, Monika Hofer, Clara Limbaeck, Gabriele C DeLuca   +10 more
wiley   +1 more source

Osmotic demyelination syndrome with normal serum sodium in an alcohol-dependent patient: a case report. [PDF]

Front Hum Neurosci
Li Y, Han L, Jiang Y, Zhao Z, Xin Z, Zhu Z.   +5 more
europepmc   +1 more source

Study on the Function and Mechanism of Neutrophil Extracellular Traps in Regulating Necroptosis Following Traumatic Brain Injury

Brain and Behavior, Volume 16, Issue 3, March 2026.
TBI induces NETs formation, as evidenced by the upregulation of PAD4 and MPO. NETs activate the necroptosis pathway via phosphorylation of RIP1‐RIP3‐MLKL, thereby exacerbating secondary brain injury (neuronal death, BBB disruption, and neuroinflammation).
Ao Li, Tian‐Wei Pei, Hao Qi, Li‐Biao Song, Juan Fang, Zhi‐Song Ding, Tao Chen   +6 more
wiley   +1 more source

소아 신경영상에서 보이는 비선천성 원인의 영상 소견: 임상 화보. [PDF]

J Korean Soc Radiol
Gala F, Jain N, Salunke N.
europepmc   +1 more source

Association Between Glymphatic Function and White Matter Microstructural Injury in Patients With Cushing's Disease

Brain and Behavior, Volume 16, Issue 3, March 2026.
This study suggests that glymphatic dysfunction is associated with white matter injury in Cushing's disease. Mediation analysis indicates that impaired glymphatic function may serve as a pathway linking elevated midnight cortisol to structural damage in the right superior longitudinal fasciculus III.
Yuxiang Sun, Junpeng Xu, Hailong Liu, Qijia Wu, Zihao Zhu, Xiaoteng Yu, Yanyang Zhang   +6 more
wiley   +1 more source

Inflammatory bowel disease therapies and demyelinating diseases: a practical guide to therapeutic benefit and risk. [PDF]

J Crohns Colitis
Honap S, Debouverie M, Filippi M, Selchen D, Jairath V, Danese S, Peyrin-Biroulet L.   +6 more
europepmc   +1 more source

Elucidating the Causal Relationships Between B Cells, Dendritic Cells, and Multiple Sclerosis Pathogenesis

Brain and Behavior, Volume 16, Issue 3, March 2026.
This study presents an integrative pipeline linking immune cell traits to multiple sclerosis (MS) susceptibility. Genome‐wide association and Mendelian randomization analyses revealed causal roles of immune cells in MS risk. Colocalization and pleiotropy mapping identified candidate genes, further refined through functional annotation, network analysis,
Xuefei Wang, Yangwei Wang, Xiaojing Liu
wiley   +1 more source

Intestinal mucosal alterations parallel central demyelination and remyelination: insights into the gut-brain axis in the cuprizone model of multiple sclerosis. [PDF]

Front Immunol
Ferreira C, Carvalho F, Vieira P, Alves A, Palavra F, Almeida J, Alves V, Coscueta E, Pereira PD, Pintado M, Sá H, Castelo-Branco M, Reis F, Viana S.   +13 more
europepmc   +1 more source

Early Microstructural Changes in the Left Inferior Fronto‐Occipital Fasciculus: A Key Factor in Probable Alzheimer's Disease Patients With Slow Gait Speed

Brain and Behavior, Volume 16, Issue 3, March 2026.
Using fixel‐based analysis in Alzheimer's disease, we found that reduced fiber density value of the left inferior fronto‐occipital fasciculus is associated with both slower gait speed and impairments in executive and visuospatial functions, suggesting this white matter tract as a shared neural substrate for cognitive‐motor decline.
Shan‐Wen Liu, Lin‐Lin Yao, Fang‐Bo Li, Xiao‐Ting Ma, Xiao‐Fen Weng, Meng Li, Jiangtao Zhu, Chun‐Feng Liu, Chun‐Yuan Zhang, Hua Hu   +9 more
wiley   +1 more source

Remyelination as a therapeutic target in the treatment of multiple sclerosis. [PDF]

AIMS Neurosci
Garcha GK, Ahmed M.
europepmc   +1 more source