Results 211 to 220 of about 97,922 (342)

Transcription‐coupled repair: tangled up in convoluted repair

The FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher, Yun Jin Pai, Alex Pines, Wim Vermeulen   +3 more
wiley   +1 more source

Targeting HDAC3 Suppresses Ferroptosis and Demyelination in White Matter Injury by Restoring PDK4-Mediated Iron Homeostasis. [PDF]

CNS Neurosci Ther
Xu T, Ye L, Li W, Liu F, Wei T, Gu W, Xu L, Fang M, Luo Q, Wu C, Wang G.   +10 more
europepmc   +1 more source

Tyro3 deletion is protective in experimental autoimmune encephalomyelitis

Immunology &Cell Biology, EarlyView.
Multiple sclerosis pathogenesis involves the complex interplay between the peripheral immune response and the central nervous system. Gas6 is a promising therapy to promote remyelination; however, Gas6 and its receptors (the TAM receptor family) are widely expressed in both immune cells and the central nervous system. Our study demonstrates that global
Michele D Binder, Mohammad Asadian, Darnell Leepel, Gerry ZM Ma, Andrea Aprico, Liz Barreto‐Arce, Trevor J Kilpatrick, Sarrabeth Stone   +7 more
wiley   +1 more source

Lipid-Laden Microglia: Characterization and Roles in Diseases. [PDF]

Cells
Xing J, McKenzie T, Hu J.
europepmc   +1 more source

Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin‐induced demyelination [PDF]

, 2001
Mark Kotter, Anna Setzu, Fraser J. Sim, Nico van Rooijen, Robin J.M. Franklin   +4 more
openalex   +1 more source

MRI‐based surrogates of brain clearance in narcolepsy type 1

Journal of Sleep Research, EarlyView.
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese, Jari K. Gool, Gert Jan Lammers, Ysbrand D. van der Werf, Matthias J. P. van Osch, Rolf Fronczek, Lydiane Hirschler   +6 more
wiley   +1 more source

Mechanosensitive Piezo1 channel: an emerging target in demyelination disease. [PDF]

Front Cell Neurosci
Zhang Y, Yang X, Deng S, Wang C, Hu J, Lan Q.   +5 more
europepmc   +1 more source

Glial Growth Factor/Neuregulin Inhibits Schwann Cell Myelination and Induces Demyelination [PDF]

, 2001
George Zanazzi, Steven Einheber, Richard Westreich, Melanie‐Jane Hannocks, Debra Bedell-Hogan, Mark A. Marchionni, James L. Salzer   +6 more
openalex   +1 more source

Homeostatic Influence of Fig4 Outside of the Fab1‐Vac14‐Fig4 Complex in Saccharomyces cerevisiae

Molecular Microbiology, EarlyView.
Disease‐related Fig4 mutants displaying impaired association with the Fab1‐Vac14‐Fig4 complex confer rapamycin tolerance in Saccharomyces cerevisiae independent of Vac14 and Fig4 catalytic function. Fig4 may thus modulate homeostasis through uncharacterized molecular interactions that lead to altered function when not bound to Vac14. ABSTRACT The lipid
Hannah E. Reeves, Anna King, Imran Khan, Asha Thomas, Corey Chung, Anirudan Sivaprakash, Harrison A. Hall, Cole McGuire, Victoria Cruz, Alim Habib, Lauren Dotson, Sophia R. Lee, Caroline L. Darbro, Bethany S. Strunk   +13 more
wiley   +1 more source

Osmotic Demyelination Syndrome Following Rapid Correction of Hyponatremia in a Young Woman: A Case Report and Review of Literature. [PDF]

Cureus
Akram A, Muhammad US, Ali AM, Rizvi FM.
europepmc   +1 more source