Results 131 to 140 of about 43,848 (310)

Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

Journal of Pharmacy and Bioallied Sciences, 2014
Dendrimers are the emerging polymeric architectures that are known for their defined structures, versatility in drug delivery and high functionality whose properties resemble with biomolecules.
Kanika Madaan, Sandeep Kumar, Neelam Poonia, Viney Lather, D. Pandita   +4 more
semanticscholar   +1 more source

Functional Dendrimer Nanogels for DNA Delivery and Gene Therapy of Tumors

Angewandte Chemie International Edition, Accepted Article.
Solving the dilemma between efficacy and cytotoxicity of cationic colloidal vectors is one of the biggest challenges in gene delivery. Cationic dendrimer assemblies with hierarchical structure, smart and biomimetic behaviors have been developed for drug/gene delivery in vivo.
Xin Li, Zhijun Ouyang, Laura Hetjens, Ming Ni, Kuailu Lin, Yong Hu, Xiangyang Shi, Andrij Pich   +7 more
wiley   +1 more source

Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. [PDF]

, 1996
Jolanta F. Kukowska‐Latallo, Anna U. Bielinska, James M. Johnson, Ralf Spindler, Donald A Tomalia, James R. Baker   +5 more
openalex   +1 more source

Efficient Synthesis of Macromolecular DO3A@Gn Derivatives for Potential Application in MRI Diagnostics: From Polymer Conjugates to Polymer Nanoparticles

Macromolecular Chemistry and Physics, Volume 224, Issue 1, January 2023., 2023
Herein, poly(2‐oxazoline) homo‐ and copolymers are used for functionalization with the 1,4,7,10‐tetraazacyclododecane‐N,N,N,N‐tetraacetic acid chelator and subsequent complexation with Gn(III). The resulting conjugates are utilized for micelle and nanoparticle formation and are further analyzed and compared toward their relaxivity as a prerequisite for
Anne‐Larissa Kampmann, Wolf Hiller, Ralf Weberskirch   +2 more
wiley   +1 more source

Five Generations of Nitroxyl-Functionalized Dendrimers [PDF]

, 1997
Anton W. Bosman, René A. J. Janssen, E. W. Meijer   +2 more
openalex   +1 more source

Photo‐Curable Triazinetrione Composites With Tunable Degradation for Fracture Stabilization and Flexible Thin‐Film Applications

Journal of Applied Polymer Science, EarlyView.
Injectable photo‐curable composites are emerging as an attractive alternative to address the limitations of metal plates in fracture fixation. Their customizable composition makes them highly adaptable for a wide range of biomedical applications. By incorporating hydrolysable linkages into the polymeric network and combining them with inorganic fillers
Jorge San Jacinto Garcia, Natalia Sanz del Olmo, Daniel J. Hutchinson, Michael Malkoch   +3 more
wiley   +1 more source

Comb and Branch‐on‐Branch Model Polystyrenes with Exceptionally High Strain Hardening Factor SHF > 1000 and Their Impact on Physical Foaming

Macromolecular Chemistry and Physics, Volume 224, Issue 1, January 2023., 2023
Anionically synthesized monodisperse model polystyrenes with comb and dendrigraft‐like branch‐on‐branch architectures exhibit tremendously high strain hardening factors in uniaxial elongation in the order of 2–3 decades. Batch foaming is used to investigate the extensional properties under practical aspects.
Lorenz Faust, Marie‐Christin Röpert, Masood K. Esfahani, Mahdi Abbasi, Valerian Hirschberg, Manfred Wilhelm   +5 more
wiley   +1 more source

Anti-Inflammatory Properties of Dendrimers per se

The Scientific World Journal, 2011
Dendrimers are polybranched and polyfunctionalized tree-like polymers. Unlike linear polymers, they have perfectly defined structure and molecular weight, due to their iterative step-by-step synthesis.
Myriam Hayder, Séverine Fruchon, Jean-Jacques Fournié, Mary Poupot, Rémy Poupot   +4 more
doaj   +1 more source

DNA Condensation by Partially Acetylated Poly(amido amine) Dendrimers: Effects of Dendrimer Charge Density on Complex Formation

Molecules, 2013
The ability of poly(amido amine) (or PAMAM) dendrimers to condense semiflexible dsDNA and penetrate cell membranes gives them great potential in gene therapy and drug delivery but their high positive surface charge makes them cytotoxic. Here, we describe
Ronald G. Larson, James R. Baker, Ming-Hsin Li, Seok Ki Choi, Shi Yu   +4 more
doaj   +1 more source

Inorganic Cauliflower: Functional Main Group Element Dendrimers Constructed from Phosphorus‐ and Silicon‐Based Building Blocks [PDF]

, 1997
Dietrich Gudat
openalex   +1 more source