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Immunobiology of dendritic cells.
Annual Review of Immunology, 2000 Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary immune responses. DCs capture and transfer information from the outside world to the cells of the adaptive immune system.
J. Banchereau +7 more
semanticscholar +1 more source
Dendritic Cell Differentiation [PDF]
The Journal of Immunology, 2004 Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A +4 more
openaire +5 more sources
Journal of Experimental Medicine, 1994 Using granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin 4 we have established dendritic cell (DC) lines from blood mononuclear cells that maintain the antigen capturing and processing capacity characteristic of immature dendritic ...
F. Sallusto, A. Lanzavecchia
semanticscholar +1 more source
The disabled dendritic cell [PDF]
The FASEB Journal, 2001 Dendritic cells are important antigen-presenting cells of the immune system that induce and modulate immune responses. They interact with T and B lymphocytes as well as with natural killer cells to promote activation and differentiation of these cells.
Reinhold Ramoner +4 more
openaire +3 more sources
The discovery of dendritic cells [PDF]
Journal of Experimental Medicine, 2021 An excerpt from Ralph Steinman’s Harvey Lecture describing the discovery of dendritic cells.
openaire +3 more sources
Tolerogenic Dendritic Cells [PDF]
Annual Review of Immunology, 2003 ▪ Abstract Dendritic cells (DCs) have several functions in innate and adaptive immunity. In addition, there is increasing evidence that DCs in situ induce antigen-specific unresponsiveness or tolerance in central lymphoid organs and in the periphery. In the thymus DCs generate tolerance by deleting self-reactive T cells.
Steinman, Ralph M. +2 more
openaire +2 more sources
Dendritic Cells and Their Multiple Roles during Malaria Infection
Journal of Immunology Research, 2016 Dendritic cells (DCs) play a central role in the initiation of adaptive immune responses, efficiently presenting antigens to T cells. This ability relies on the presence of numerous surface and intracellular receptors capable of sensing microbial ...
Kelly N. S. Amorim +3 more
doaj +1 more source
Transcriptional regulation of DC fate specification [PDF]
, 2020 Dendritic cells function in the immune system to instruct adaptive immune cells to respond accordingly to different threats. While conventional dendritic cells can be subdivided into two main subtypes, termed cDC1s and cDC2s, it is clear that further ...
Bosteels, Cedric, Scott, Charlotte
core +1 more source
Journal of Experimental Medicine, 1992 Antigen-presenting, major histocompatibility complex (MHC) class II- rich dendritic cells are known to arise from bone marrow. However, marrow lacks mature dendritic cells, and substantial numbers of proliferating less-mature cells have yet to be ...
K. Inaba +7 more
semanticscholar +1 more source
Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion
Advanced Engineering Materials, EarlyView., 2023 Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal +5 more
wiley +1 more source