Results 41 to 50 of about 11,205,379 (410)
Anti-tumor immunity controlled through mRNA m6A and YTHDF1 in dendritic cells
Nature, 2019 There is growing evidence that tumour neoantigens have important roles in generating spontaneous antitumour immune responses and predicting clinical responses to immunotherapies1,2.
Dali Han +14 more
semanticscholar +1 more source
PLoS ONE, 2013 Dendritic cells are the professional antigen presenting cells of innate immunity and key players in maintaining the balance of immune responses. Studies with dendritic cells are mainly limited by their low numbers in vivo and their difficult maintenance ...
Cornelia Richter +5 more
doaj +1 more source
MOLECULAR AND CELLULAR MECHANISMS MEDIATED BY DENDRITIC CELLS INVOLVED IN THE INDUCTION OF TOLERANCE
Медицинская иммунология, 2017 Autoimmune diseases and complications after transplantation operations are major public health problem, as they often lead to deterioration in the quality of life, reduce work capacity and disability in the population.
S. V. Sennikov +3 more
doaj +1 more source
Current Opinion in Immunology, 2015 Dendritic cells (DCs) are versatile controllers of the immune system, best known for their potent ability to initiate adaptive immunity. Traditionally, DCs have been defined on the basis of cell morphology, expression of specific markers and select functional attributes such as the ability to migrate to T cell areas of secondary lymphoid organs and ...
Barbara U Schraml, Caetano Reis e Sousa
openaire +3 more sources
Nature Communications, 2019 The Wnt pathway regulates anti-tumour immunity in melanoma. Here, the authors show that, in lung adenocarcinoma, secretion of the ligand Wnt1 induces immune resistance by impairing the ability of dendritic cells to cross-prime T cells, and that blocking ...
Dimitra Kerdidani +14 more
doaj +1 more source
Exploring the functional significance of dendritic inhibition in cortical pyramidal cells [PDF]
, 2003 Inhibitory synapses contacting the soma and axon initial segment are commonly presumed to participate in shaping the response properties of cortical pyramidal cells.
Johnson, M H, Spratling, M W
core +3 more sources
Dendritic Cells and CD8 T Cell Immunity in Tumor Microenvironment
Frontiers in Immunology, 2018 Dendritic cells (DCs) play a central role in the regulation of the balance between CD8 T cell immunity vs. tolerance to tumor antigens. Cross-priming, a process which DCs activate CD8 T cells by cross-presenting exogenous antigens, plays a critical role ...
Chunmei Fu, Aimin Jiang
semanticscholar +1 more source
Annual Review of Immunology, 2013 Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes ...
M. Merad +4 more
semanticscholar +1 more source
PARTICIPATION OF DENDRITIC CELLS IN VASCULAR LESIONS OF CHRONIC REJECTION OF HUMAN ALLOGRAFTS [PDF]
, 1988 Immunohistochemical techniques were used to investigate the pathogenesis of obliterative arteriopathy, a major obstacle to long-term solid organ allograft survival.
Billingham +32 more
core +1 more source