Results 41 to 50 of about 11,507,286 (389)

Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. [PDF]

PLoS ONE, 2014
The objective of the study was to identify immune cell populations, in addition to Foxp3+ T-regulatory cells, that participate in the mechanisms of action of tolerogenic dendritic cells shown to prevent and reverse type 1 diabetes in the Non-Obese ...
Valentina Di Caro, Brett Phillips, Carl Engman, Jo Harnaha, Massimo Trucco, Nick Giannoukakis   +5 more
doaj   +1 more source

MCSF drives regulatory DC development in stromal co-cultures supporting hematopoiesis [PDF]

, 2018
Background: Splenic stroma overlaid with hematopoietic progenitors supports in vitro hematopoiesis with production of dendritic-like cells. Co-cultures of murine lineage-depleted bone marrow over the 5G3 stromal line produce two populations of cells ...
O'Neill, Helen C, Periasamy, Pravin, Petvises, Sawang   +2 more
core   +2 more sources

SnapShot: Dendritic Cells

Cell, 2011
[No abstract available]
Idoyaga, Juliana, Steinman, Ralph M.
openaire   +2 more sources

Enhanced Immunogenicity and Protective Effects against SARS-CoV-2 Following Immunization with a Recombinant RBD-IgG Chimeric Protein

Vaccines
The unprecedented global impact caused by SARS-CoV-2 imposed huge health and economic challenges, highlighting the urgent need for safe and effective vaccines.
Mariângela de Oliveira Silva, Maria Fernanda Castro-Amarante, Alexia Adrianne Venceslau-Carvalho, Bianca da Silva Almeida, Isabela Pazotti Daher, Guilherme Antonio de Souza-Silva, Marcio Massao Yamamoto, Gabriela Koike, Edmarcia Elisa de Souza, Carsten Wrenger, Luís Carlos de Souza Ferreira, Silvia Beatriz Boscardin   +11 more
doaj   +1 more source

Cigarette smoke promotes dendritic cell accumulation in COPD; a Lung Tissue Research Consortium study

Respiratory Research, 2010
Background Abnormal immune responses are believed to be highly relevant in the pathogenesis of chronic obstructive pulmonary disease (COPD). Dendritic cells provide a critical checkpoint for immunity by their capacity to both induce and suppress immunity.
Yi Eunhee S, Kottom Theodore J, Lamont Jeffrey, Walters Paula R, Vassallo Robert, Limper Andrew H   +5 more
doaj   +1 more source

A generic polymer-protein ligation strategy for vaccine delivery [PDF]

, 2016
Although the field of cancer immunotherapy is intensively investigated, there is still a need for generic strategies that allow easy, mild and efficient formulation of vaccine antigens.
De Geest, Bruno, Fierens, Kaat, Lambrecht, Bart, Lybaert, Lien, Nuhn, Lutz, Schuijs, Martijn, Vanparijs, Nane   +6 more
core   +1 more source

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products

Journal of Experimental Medicine, 1995
We have previously demonstrated that human peripheral blood low density mononuclear cells cultured in granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin (IL)-4 develop into dendritic cells (DCs) that are extremely efficient in ...
F. Sallusto, M. Cella, Carlo Danieli, A. Lanzavecchia   +3 more
semanticscholar   +1 more source

Dendritic cells during Epstein Barr virus infection

Frontiers in Microbiology, 2014
Epstein Barr virus (EBV) causes persistent infection in more than 90% of the human adult population and is associated with 2% of all tumors in humans. This -herpesvirus infects primarily human B and epithelial cells, but has been reported to be sensed ...
Christian eMunz
doaj   +1 more source

Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A. [PDF]

PLoS ONE, 2013
Dendritic cells initiate adaptive immune responses, leading either to control cancer by effector T cells or to exacerbate cancer by regulatory T cells that inhibit IFN-γ-mediated Th1-type response.
Selma Olsson Åkefeldt, Carine Maisse, Alexandre Belot, Marlène Mazzorana, Giulia Salvatore, Nathalie Bissay, Pierre Jurdic, Maurizio Aricò, Chantal Rabourdin-Combe, Jan-Inge Henter, Christine Delprat   +10 more
doaj   +1 more source

Growth of donor-derived dendritic cells from the bone marrow of murine liver auograft recipients in response to granulocyte/macrophage colony-stimulating factor [PDF]

, 1995
Allografts of the liver, which has a comparatively heavy leukocyte content compared with other vascularized organs, are accepted permanently across major histocompatibility complex barriers in many murine strain combinations without immunosuppressive ...
Fu, F, Fung, JJ, Lu, L, McCaslin, D, Qian, S, Rao, AS, Rudert, WA, Starzl, TE, Thomson, AW, Trucco, M   +9 more
core   +1 more source