Results 81 to 90 of about 11,507,286 (389)
Plasmacytoid dendritic cells in dermatology, [PDF]
Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and ...
Natasha Favoretto Dias de Oliveira +3 more
doaj +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Background Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid dendritic cell activation are both encountered in common inflammatory disorders.
Fanny Angelot +10 more
doaj +1 more source
Maturation of Dendritic Cells [PDF]
Introduction to Dendritic Cells: Maturatin of Dendritic Cellshttps://digitalcommons.rockefeller.edu/introduction-dendritic-cells/1005/thumbnail ...
Laboratory, Steinman
core +1 more source
Reply to ‘Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature’ [PDF]
Loems Ziegler‐Heitbrock +4 more
openalex +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Different Life Cycle Stages of Plasmodium falciparum Induce Contrasting Responses in Dendritic Cells
Dendritic cells are key linkers of innate and adaptive immunity. Efficient dendritic cell activation is central to the acquisition of immunity and the efficacy of vaccines.
Xi Zen Yap +11 more
doaj +1 more source
Migration of Dendritic Cells [PDF]
Introduction to Dendritic Cells: Migratin of Dendritic Cellshttps://digitalcommons.rockefeller.edu/introduction-dendritic-cells/1006/thumbnail ...
Laboratory, Steinman
core +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source

