TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent [PDF]
, 2008 Toll-like receptor (TLR) signaling induces a rapid reorganization of the actin cytoskeleton in cultured mouse dendritic cells (DC), leading to enhanced antigen endocytosis and a concomitant loss of filamentous actin–rich podosomes.
Chan, Kui Ming +6 more
core +5 more sources
Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]
, 2015 Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables.
Ahmad, Subutai, Hawkins, Jeff
core +3 more sources
Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]
, 2013 The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M. +7 more
core
Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]
, 2018 Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico +11 more
core +1 more source
Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin. [PDF]
, 2017 Human skin consists of multiple cell types, including epithelial, immune, and stromal cells. Transcriptomic analyses have previously been performed from bulk skin samples or from epithelial and immune cells expanded in cell culture.
Ahn, Richard S +9 more
core +1 more source
Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations [PDF]
, 2003 Electrical coupling between pyramidal cell axons, and between interneuron dendrites, have both been described in the hippocampus. What are the functional roles of the two types of coupling?
Bibbig, A. +7 more
core +2 more sources
PLoS ONE, 2013 CYTIP (cytohesin interacting protein) is an intracellular molecule induced in dendritic cells during maturation. CYTIP modulates the binding intensity of the adhesion molecule LFA-1.
Daniela Grabher +3 more
doaj +1 more source
Dendritic Cells and Vaccines [PDF]
Baylor University Medical Center Proceedings, 2008 Note: Dr. Steinman received the prestigious 2007 Albert Lasker Award for Basic Medical Research for the discovery of dendritic cells. The award committee called him “a scientific sleuth, who without cloak and dagger, uncovered the intelligence-gathering component of our immune system—a monumental achievement in the 200-year history of immunology.” Dr ...
openaire +3 more sources
Microchimerism, dendritic cell progenitors and transplantation tolerance [PDF]
, 1995 The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients up to three decades after organ transplantation implies the migration and survival of donor stem cells within the host.
Demetris, AJ +5 more
core +1 more source
Generation of Mouse Bone Marrow-Derived Dendritic Cells (BM-DCs)
Bio-Protocol, 2012 Generating mouse dendritic cells from bone-marrow progenitor cells is a useful tool to study biological functions of mouse dendritic cells. Dendritic cells are one of the major populations of phagocytes able to activate both innate and adaptive immune ...
Francesca Granucci +2 more
doaj +1 more source