Results 1 to 10 of about 87,585 (230)
Effects of Tropomodulin 2 on Dendritic Spine Reorganization and Dynamics [PDF]
Biomolecules, 2023 Dendritic spines are actin-rich protrusions that receive a signal from the axon at the synapse. Remodeling of cytoskeletal actin is tightly connected to dendritic spine morphology-mediated synaptic plasticity of the neuron.
Balaganesh Kuruba +6 more
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The role of dendritic spines in epileptogenesis
Frontiers in Cellular Neuroscience, 2023 Epilepsy is a chronic central nervous system (CNS) disease associated with high morbidity. To date, there is no known disease-modifying therapy for epilepsy.
Gary Jean +4 more
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Effects of cholestasis and hyperammonemia on dendritic spine density and turnover in rat hippocampal neurons [PDF]
Scientific ReportsAdults and children with cholestatic liver disease are at risk for type C hepatic encephalopathy (HE) and may present lifelong neurocognitive impairment.
Laurianne Giovannoni +6 more
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Assessing protein distribution and dendritic spine morphology relationships using structured illumination microscopy in cultured neurons [PDF]
STAR ProtocolsSummary: Dendritic spines are protrusions on dendrites forming the postsynaptic aspect of excitatory connections within the brain. Spine morphology is associated with synaptic functional strength and the spatial regulation of protein nanodomains within ...
Kathryn J. Bjornson, Michael E. Cahill
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Neurodevelopmental disorder-associated ZBTB20 gene variants affect dendritic and synaptic structure. [PDF]
PLoS ONE, 2018 Dendritic spine morphology and dendritic arborization are key determinants of neuronal connectivity and play critical roles in learning, memory and behavior function.
Kelly A Jones +8 more
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Superresolving Dendritic Spines [PDF]
Biophysical Journal, 2013 Spines are tiny protrusions that densely stud the dendrites of neurons in the brain. Individual spines are the primary recipients of synaptic inputs from single axons, which emanate from other neurons in the central nervous system. A dendritic tree on one neuron may have hundreds of thousands of spines, making connections to a corresponding number of ...
Loew, Leslie M., Hell, Stefan
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Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling. [PDF]
PLoS ONE, 2015 During development, scaffold proteins serve as important platforms for orchestrating signaling complexes to transduce extracellular stimuli into intracellular responses that regulate dendritic spine morphology and function.
Yu Chen +8 more
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PLoS Computational Biology, 2022 Dendritic spines are highly dynamic neuronal compartments that control the synaptic transmission between neurons. Spines form ultrastructural units, coupling synaptic contact sites to the dendritic shaft and often harbor a spine apparatus organelle ...
James Rosado +5 more
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Cells, 2021 Dendritic spines are small, bulbous protrusions along neuronal dendrites where most of the excitatory synapses are located. Dendritic spine density in normal human brain increases rapidly before and after birth achieving the highest density around 2–8 ...
Pushpa Khanal, Pirta Hotulainen
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Pathology of Synapses and Dendritic Spines [PDF]
Neural Plasticity, 2012 Peer ...
Shira Knafo +3 more
openaire +6 more sources