Results 31 to 40 of about 94,485 (200)
Ecotoxicology and Environmental Safety, 2023 Lead (Pb), cadmium (Cd), and mercury (Hg) are environmentally toxic heavy metals that can be simultaneously detected at low levels in the blood of the general population. Although our previous studies have demonstrated neurodevelopmental toxicity upon co-
Fankun Zhou +17 more
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Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system [PDF]
, 2016 During brain development, dynamic changes in neuronal membranes perform critical roles in neuronal morphogenesis and migration to create functional neural circuits.
Ko, Kwang Woo +5 more
core +2 more sources
Disease Models & Mechanisms, 2022 Dendritic spines are the principal site of excitatory synapse formation in the human brain. Several neurodevelopmental disorders cause spines to develop abnormally, resulting in altered spine number and morphology.
Elisabeth C. DeMarco +2 more
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Travelling waves in a model of quasi-active dendrites with active spines [PDF]
, 2010 Dendrites, the major components of neurons, have many different types of branching structures and are involved in receiving and integrating thousands of synaptic inputs from other neurons.
Abbott +40 more
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Dendritic spine pathology in schizophrenia [PDF]
Neuroscience, 2013 Schizophrenia is a neurodevelopmental disorder whose clinical features include impairments in perception, cognition and motivation. These impairments reflect alterations in neuronal circuitry within and across multiple brain regions that are due, at least in part, to deficits in dendritic spines, the site of most excitatory synaptic connections ...
J R, Glausier, D A, Lewis
openaire +2 more sources
Neural Plasticity, 2012 Alterations in dendritic spines have been documented in numerous neurodevelopmental disorders, including Rett Syndrome (RTT). RTT, an X chromosome-linked disorder associated with mutations in MECP2, is the leading cause of ...
Christopher A. Chapleau +5 more
doaj +1 more source
The role of dendritic spines in epileptogenesis
Frontiers in Cellular Neuroscience, 2023 Epilepsy is a chronic central nervous system (CNS) disease associated with high morbidity. To date, there is no known disease-modifying therapy for epilepsy.
Gary Jean +4 more
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A Dynamin-3 Spliced Variant Modulates the Actin/Cortactin-Dependent Morphogenesis of Dendritic Spines [PDF]
, 2005 Immature dendrites extend many actin-rich filopodial structures that can be replaced by synapse-containing dendritic spines as the neuron matures. The large GTPase dynamin-3 (Dyn3) is a component of the postsynapse in hippocampal neurons but its function
Chen, Jing +3 more
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Lipid dynamics at dendritic spines [PDF]
Frontiers in Neuroanatomy, 2014 Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine plasticity.
Dotti, Carlos Gerardo +2 more
openaire +4 more sources
NeuroImageMemory is closely associated with neuronal activity and dendritic spine formation. Low-intensity transcranial ultrasound stimulation (TUS) improves the memory of individuals with vascular dementia (VD).
Jiamin Pei +5 more
doaj +1 more source