Results 31 to 40 of about 87,585 (230)

Travelling waves in a model of quasi-active dendrites with active spines [PDF]

, 2010
Dendrites, the major components of neurons, have many different types of branching structures and are involved in receiving and integrating thousands of synaptic inputs from other neurons.
Abbott, Alvarez, Baer, Bhatt, Bloodgood, Bressloff, Brown, Cajal, Cook, Coombes, Coombes, Coombes, Coombes, Coombes, Cox, Hodgkin, James, Johnston, Katz, Koch, Larkum, Lord, Magee, Mauro, Mel, Miller, Miller, Narayanan, Scott, Segal, Segev, Shepherd, Spruston, Svoboda, Timofeeva, Timofeeva, Timofeeva, Tsay, Ulrich, Williams, Y. Timofeeva   +40 more
core   +1 more source

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

Neurobiology of Disease, 2009
Rett syndrome (RTT) is an X chromosome-linked neurodevelopmental disorder associated with the characteristic neuropathology of dendritic spines common in diseases presenting with mental retardation (MR).
Christopher A. Chapleau, Gaston D. Calfa, Meredith C. Lane, Asher J. Albertson, Jennifer L. Larimore, Shinichi Kudo, Dawna L. Armstrong, Alan K. Percy, Lucas Pozzo-Miller   +8 more
doaj   +1 more source

Hippocampal structural plasticity accompanies the resulting contextual fear memory following stress and fear conditioning [PDF]

, 2013
The present research investigated the resulting contextual fear memory and structural plasticity changes in the dorsal hippocampus (DH) following stress and fear conditioning. This combination enhanced fear retention and increased the number of total and
Calfa, Gaston Diego, Giachero, Marcelo, Molina, Víctor Alejandro   +2 more
core   +1 more source

ApoE receptor 2 regulates synapse and dendritic spine formation.

PLoS ONE, 2011
BackgroundApolipoprotein E receptor 2 (ApoEr2) is a postsynaptic protein involved in long-term potentiation (LTP), learning, and memory through unknown mechanisms.
Sonya B Dumanis, Hyun-Jung Cha, Jung Min Song, Justin H Trotter, Matthew Spitzer, Ji-Yun Lee, Edwin J Weeber, R Scott Turner, Daniel T S Pak, G William Rebeck, Hyang-Sook Hoe   +10 more
doaj   +1 more source

Co-exposure to low-dose lead, cadmium, and mercury promotes memory deficits in rats: Insights from the dynamics of dendritic spine pruning in brain development

Ecotoxicology and Environmental Safety, 2023
Lead (Pb), cadmium (Cd), and mercury (Hg) are environmentally toxic heavy metals that can be simultaneously detected at low levels in the blood of the general population. Although our previous studies have demonstrated neurodevelopmental toxicity upon co-
Fankun Zhou, Lu Ouyang, Jie Xie, Sisi Liu, Qi Li, Shuo Yang, Jiajun Li, Rui Su, Shaoqi Rao, Lingyu Yan, Xin Wan, Hui Cheng, Peishan Liu, Lingling Li, Yanhui Zhu, Guihua Du, Chang Feng, Guangqin Fan   +17 more
doaj   +1 more source

Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation [PDF]

, 2013
Dendritic spines are major sites of excitatory synaptic transmission and changes in their numbers and morphology have been associated with neurodevelopmental and neurodegenerative disorders.
Galati, DF, Hiester, BG, Jones, KR, Salinas, PC   +3 more
core   +1 more source

Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study [PDF]

, 2018
Indexación: Scopus.Laboratory of Neuroplasticity and Neurogenetics, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile, 2Laboratorio Farmacología del Comportamiento ...
Ana M. Avalos, Ana M. Avalos, Aníbal Pacheco, Esteban Aliaga, Felipe Antonio Olave, Felipe Ignacio Aguayo, Gabriela Díaz-Véliz, Gonzalo García-Rojo, Jenny Lucy Fiedler, José L. Ulloa, Luciano Román-Albasini, Macarena Tejos-Bravo, Paulina S. Rojas, Wladimir Corrales   +13 more
core   +2 more sources

Lamina-specific AMPA receptor dynamics following visual deprivation in vivo. [PDF]

, 2020
Regulation of AMPA receptor (AMPAR) expression is central to synaptic plasticity and brain function, but how these changes occur in vivo remains elusive.
Cudmore, Robert H, Graves, Austin R, Huganir, Richard L, Roth, Richard H, Tan, Han L   +4 more
core   +2 more sources

The discovery of dendritic spines by Cajal [PDF]

Frontiers in Neuroanatomy, 2015
Dendritic spines were considered an artifact of the Golgi method until a brash Spanish histologist, Santiago Ramón y Cajal, bet his scientific career arguing that they were indeed real, correctly deducing their key role in mediating synaptic connectivity.
openaire   +4 more sources

Synapses and Dendritic Spines as Pathogenic Targets in Alzheimer’s Disease

Neural Plasticity, 2012
Synapses are sites of cell-cell contacts that transmit electrical or chemical signals in the brain. Dendritic spines are protrusions on dendritic shaft where excitatory synapses are located.
Wendou Yu, Bingwei Lu
doaj   +1 more source