Results 41 to 50 of about 94,485 (200)
Dendritic Spines in the Spinal Cord: Live Action Pain
Neuroscience Insights, 2020 Dendritic spines are microscopic protrusions on neurons that house the postsynaptic machinery necessary for neurotransmission between neurons. As such, dendritic spine structure is intimately linked with synaptic function.
Curtis A Benson +2 more
doaj +1 more source
Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density. [PDF]
PLoS ONE, 2016 The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators of neuronal structure and function. Although these receptors share common signaling pathways, they are capable of having distinct effects on cellular plasticity ...
Kellie S Gross +5 more
doaj +1 more source
Dendritic Spine Shape Analysis: A Clustering Perspective [PDF]
, 2016 Functional properties of neurons are strongly coupled with their morphology. Changes in neuronal activity alter morphological characteristics of dendritic spines.
A Govindarajan +30 more
core +2 more sources
Dopaminergic signaling in dendritic spines [PDF]
Biochemical Pharmacology, 2008 Dopamine regulates movement, motivation, reward, and learning and is implicated in numerous neuropsychiatric and neurological disorders. The action of dopamine is mediated by a family of seven-transmembrane G protein-coupled receptors encoded by at least five dopamine receptor genes (D1, D2, D3, D4, and D5), some of which are major molecular targets ...
Wei-Dong, Yao +2 more
openaire +2 more sources
Three-dimensional spatial modeling of spines along dendritic networks in human cortical pyramidal neurons. [PDF]
PLoS ONE, 2017 We modeled spine distribution along the dendritic networks of pyramidal neurons in both basal and apical dendrites. To do this, we applied network spatial analysis because spines can only lie on the dendritic shaft.
Laura Anton-Sanchez +5 more
doaj +1 more source
The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning. [PDF]
, 2017 Neuronal ApoE receptors are linked to learning and memory, but the pathways governing their abundance, and the mechanisms by which they affect the function of neural circuits are incompletely understood.
Achiro, Jennifer M +9 more
core +3 more sources
Cell Reports, 2019 Summary: During development, the precise implementation of molecular programs is a key determinant of proper dendritic development. Here, we demonstrate that canonical Wnt signaling is active in dendritic bundle-forming layer II pyramidal neurons of the ...
Beatrice Viale +10 more
doaj +1 more source
EphA7 isoforms differentially regulate cortical dendrite development.
PLoS ONE, 2020 The shape of a neuron facilitates its functionality within neural circuits. Dendrites integrate incoming signals from axons, receiving excitatory input onto small protrusions called dendritic spines.
Carrie E Leonard +4 more
doaj +1 more source
Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study [PDF]
, 2018 Indexación: Scopus.Laboratory of Neuroplasticity and Neurogenetics, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile, 2Laboratorio Farmacología del Comportamiento ...
Ana M. Avalos +13 more
core +2 more sources
Cadherin Regulates Dendritic Spine Morphogenesis [PDF]
Neuron, 2002 Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are thought to be a regulator of such a process. We examined the effects of cadherin blockage on synaptogenesis in cultured hippocampal neurons.
Togashi, Hideru +5 more
openaire +2 more sources