Results 1 to 10 of about 553,059 (371)
Electrical advantages of dendritic spines. [PDF]
PLoS ONE, 2012 Many neurons receive excitatory glutamatergic input almost exclusively onto dendritic spines. In the absence of spines, the amplitudes and kinetics of excitatory postsynaptic potentials (EPSPs) at the site of synaptic input are highly variable and depend
Allan T Gulledge +2 more
doaj +7 more sources
Dendritic Spines Shape Analysis—Classification or Clusterization? Perspective
Frontiers in Synaptic Neuroscience, 2020 Dendritic spines are small protrusions from the dendrite membrane, where contact with neighboring axons is formed in order to receive synaptic input.
Ekaterina Pchitskaya +2 more
doaj +2 more sources
SpineTool is an open-source software for analysis of morphology of dendritic spines [PDF]
Scientific Reports, 2023 Dendritic spines form most excitatory synaptic inputs in neurons and these spines are altered in many neurodevelopmental and neurodegenerative disorders.
Ekaterina Pchitskaya +4 more
doaj +2 more sources
Nature Communications, 2016 Transport of cargo into dendritic spines is required for synaptic plasticity. McVicker et al.describe a method of activity-dependent transport of a kinesin KIF1A and its cargo synaptotagmin-IV along microtubules that are transiently polymerized into ...
Derrick P. McVicker +7 more
doaj +2 more sources
DeepD3, an open framework for automated quantification of dendritic spines. [PDF]
PLoS Computational BiologyDendritic spines are the seat of most excitatory synapses in the brain, and a cellular structure considered central to learning, memory, and activity-dependent plasticity.
Martin H P Fernholz +3 more
doaj +2 more sources
Matrix metalloproteinase-9 involvement in the structural plasticity of dendritic spines.
Frontiers in Neuroanatomy, 2014 Dendritic spines are the locus for excitatory synaptic transmission in the brain and thus play a major role in neuronal plasticity. The ability to alter synaptic connections includes volumetric changes in dendritic spines that are driven by scaffolds ...
Michal eStawarski +2 more
doaj +2 more sources
Structural basis of long-term potentiation in single dendritic spines [PDF]
Nature, 2004 M. Matsuzaki +3 more
semanticscholar +2 more sources
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
Neuron, 2021 Psilocybin is a serotonergic psychedelic with untapped therapeutic potential. There are hints that the use of psychedelics can produce neural adaptations, although the extent and time scale of the impact in a mammalian brain are unknown.
Ling-Xiao Shao +6 more
semanticscholar +1 more source
Voltage compartmentalization in dendritic spines in vivo
Science, 2021 Description Dendritic spines’ electrical function? Dendritic spines are small protrusions that cover the dendrites of most neurons in the brain. Their electrical properties are still controversially discussed. Cornejo et al.
V. Cornejo, N. Ofer, R. Yuste
semanticscholar +1 more source
Frontiers in Cellular Neuroscience, 2023 Dendritic spines are highly dynamic structures whose structural and functional fluctuations depend on multiple factors. Changes in synaptic strength are not limited to synapses directly involved in specific activity patterns.
Ali Özgür Argunsah +2 more
doaj +1 more source