Results 11 to 20 of about 43,830 (285)
Cadherin Regulates Dendritic Spine Morphogenesis [PDF]
Neuron, 2002 Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are thought to be a regulator of such a process. We examined the effects of cadherin blockage on synaptogenesis in cultured hippocampal neurons.
Hideru Togashi +5 more
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Superresolving Dendritic Spines [PDF]
Biophysical Journal, 2013 Spines are tiny protrusions that densely stud the dendrites of neurons in the brain. Individual spines are the primary recipients of synaptic inputs from single axons, which emanate from other neurons in the central nervous system. A dendritic tree on one neuron may have hundreds of thousands of spines, making connections to a corresponding number of ...
Loew, Leslie M., Hell, Stefan
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Electrical properties of dendritic spines. [PDF]
Biophys J, 2023 Dendritic spines are small protrusions that mediate most of the excitatory synaptic transmission in the brain. Initially, the anatomical structure of spines has suggested that they serve as isolated biochemical and electrical compartments. Indeed, following ample experimental evidence, it is now widely accepted that a significant physiological role of ...
Zecevic D.
europepmc +3 more sources
Electrical advantages of dendritic spines. [PDF]
PLoS ONE, 2012 Many neurons receive excitatory glutamatergic input almost exclusively onto dendritic spines. In the absence of spines, the amplitudes and kinetics of excitatory postsynaptic potentials (EPSPs) at the site of synaptic input are highly variable and depend
Allan T Gulledge +2 more
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Frontiers in Neuroscience, 2022 Sevoflurane has become one of the most widely used volatile anesthetics in pediatric surgery. However, sevoflurane exposure may interfere with dendritic development and synaptogenesis, resulting in brain function impairment.
Linhong Zhong +6 more
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Increased spine PIP3 is sequestered from dendritic shafts
Molecular Brain, 2022 Phosphatidylinositol 3,4,5-trisphosphate (PIP3) is a lipid second messenger that is crucial for the synaptic plasticity underlying learning and memory in pyramidal neurons in the brain. Our previous study uncovered PIP3 enrichment in the dendritic spines
Yoshibumi Ueda +2 more
doaj +1 more source
St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2019 Neuronal cells are characterized by a close relationship between their functional state and morphology, especially such mobile structures as dendritic spines.
Pchitskaya Ekaterina +4 more
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Spiny and Non-spiny Parvalbumin-Positive Hippocampal Interneurons Show Different Plastic Properties
Cell Reports, 2019 Summary: Dendritic spines control synaptic transmission and plasticity by augmenting post-synaptic potentials and providing biochemical compartmentalization.
Angelica Foggetti +4 more
doaj +1 more source
eLife, 2023 Microglia, the resident immune cells of the brain, play a complex role in health and disease. They actively survey the brain parenchyma by physically interacting with other cells and structurally shaping the brain.
Felix Christopher Nebeling +6 more
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Small, smaller… dendritic spine [PDF]
The EMBO Journal, 2014 Spines are highly motile protrusions emerging from the dendritic shafts of neurons. The dynamics of these post‐synaptic structures are ruled by actin filament turnover. However, our understanding of the mechanisms of actin polymerization in dendritic spines is quite ambiguous.
Pietro, Pilo Boyl, Walter, Witke
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