Results 31 to 40 of about 43,830 (285)
Morphological analysis of dendrites and spines by hybridization of ridge detection with twin support vector machine [PDF]
PeerJ, 2016 Dendritic spines are described as neuronal protrusions. The morphology of dendritic spines and dendrites has a strong relationship to its function, as well as playing an important role in understanding brain function.
Shuihua Wang +6 more
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Neural Regeneration Research, 2023 Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and memory. Kinesin-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with ...
Shi-Yan Sun +7 more
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Dendritic spine pathology in schizophrenia [PDF]
Neuroscience, 2013 Schizophrenia is a neurodevelopmental disorder whose clinical features include impairments in perception, cognition and motivation. These impairments reflect alterations in neuronal circuitry within and across multiple brain regions that are due, at least in part, to deficits in dendritic spines, the site of most excitatory synaptic connections ...
J R, Glausier, D A, Lewis
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Lipid dynamics at dendritic spines [PDF]
Frontiers in Neuroanatomy, 2014 Dynamic changes in the structure and composition of the membrane protrusions forming dendritic spines underlie memory and learning processes. In recent years a great effort has been made to characterize in detail the protein machinery that controls spine plasticity.
Dotti, Carlos Gerardo +2 more
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PLoS Biology, 2020 The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition.
Max Mueller, Veronica Egger
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Dendritic Spines Shape Analysis—Classification or Clusterization? Perspective
Frontiers in Synaptic Neuroscience, 2020 Dendritic spines are small protrusions from the dendrite membrane, where contact with neighboring axons is formed in order to receive synaptic input.
Ekaterina Pchitskaya +2 more
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SPIN90 phosphorylation modulates spine structure and synaptic function. [PDF]
PLoS ONE, 2013 The correct rearrangement of postsynaptic components in dendritic spines is important for driving changes of spine structure and synaptic function. SPIN90 plays an essential role in many cellular processes including actin polymerization, endocytosis ...
In Ha Cho +5 more
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Dopaminergic signaling in dendritic spines [PDF]
Biochemical Pharmacology, 2008 Dopamine regulates movement, motivation, reward, and learning and is implicated in numerous neuropsychiatric and neurological disorders. The action of dopamine is mediated by a family of seven-transmembrane G protein-coupled receptors encoded by at least five dopamine receptor genes (D1, D2, D3, D4, and D5), some of which are major molecular targets ...
Wei-Dong, Yao +2 more
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Frontiers in Cellular Neuroscience, 2018 Many actin cytoskeleton-regulating proteins control dendritic spine morphology and density, which are cellular features often altered in autism spectrum disorder (ASD).
Iryna Hlushchenko +7 more
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Actin capping protein regulates postsynaptic spine development through CPI-motif interactions
Frontiers in Molecular Neuroscience, 2022 Dendritic spines are small actin-rich protrusions essential for the formation of functional circuits in the mammalian brain. During development, spines begin as dynamic filopodia-like protrusions that are then replaced by relatively stable spines ...
Kenneth R. Myers +6 more
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