Results 61 to 70 of about 553,059 (371)

Investigating sub-spine actin dynamics in rat hippocampal neurons with super-resolution optical imaging.

open access: yesPLoS ONE, 2009
Morphological changes in dendritic spines represent an important mechanism for synaptic plasticity which is postulated to underlie the vital cognitive phenomena of learning and memory.
Vedakumar Tatavarty   +3 more
doaj   +1 more source

KLHL17/Actinfilin, a brain-specific gene associated with infantile spasms and autism, regulates dendritic spine enlargement

open access: yesJournal of Biomedical Science, 2020
Background Dendritic spines, the actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain. Many actin-regulating molecules modulate dendritic spine morphology.
Hsiao-Tang Hu   +2 more
doaj   +1 more source

SPIN90 phosphorylation modulates spine structure and synaptic function. [PDF]

open access: yesPLoS ONE, 2013
The correct rearrangement of postsynaptic components in dendritic spines is important for driving changes of spine structure and synaptic function. SPIN90 plays an essential role in many cellular processes including actin polymerization, endocytosis ...
In Ha Cho   +5 more
doaj   +1 more source

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

open access: yesNeural Regeneration Research, 2023
Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and memory. Kinesin-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with ...
Shi-Yan Sun   +7 more
doaj   +1 more source

Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study [PDF]

open access: yes, 2018
Indexación: Scopus.Laboratory of Neuroplasticity and Neurogenetics, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile, 2Laboratorio Farmacología del Comportamiento ...
Ana M. Avalos   +13 more
core   +2 more sources

Morphological analysis of dendrites and spines by hybridization of ridge detection with twin support vector machine [PDF]

open access: yesPeerJ, 2016
Dendritic spines are described as neuronal protrusions. The morphology of dendritic spines and dendrites has a strong relationship to its function, as well as playing an important role in understanding brain function.
Shuihua Wang   +6 more
doaj   +2 more sources

Astrocytic Coverage of Dendritic Spines, Dendritic Shafts, and Axonal Boutons in Hippocampal Neuropil

open access: yesFrontiers in Cellular Neuroscience, 2018
Distal astrocytic processes have a complex morphology, reminiscent of branchlets and leaflets. Astrocytic branchlets are rod-like processes containing mitochondria and endoplasmic reticulum, capable of generating inositol-3-phosphate (IP3)-dependent Ca2+
N. Gavrilov   +5 more
semanticscholar   +1 more source

Dendritic integration in olfactory bulb granule cells upon simultaneous multispine activation: Low thresholds for nonlocal spiking activity.

open access: yesPLoS Biology, 2020
The inhibitory axonless olfactory bulb granule cells form reciprocal dendrodendritic synapses with mitral and tufted cells via large spines, mediating recurrent and lateral inhibition.
Max Mueller, Veronica Egger
doaj   +1 more source

Dendritic Spines in Depression: What We Learned from Animal Models

open access: yesJournal of Neural Transplantation and Plasticity, 2016
Depression, a severe psychiatric disorder, has been studied for decades, but the underlying mechanisms still remain largely unknown. Depression is closely associated with alterations in dendritic spine morphology and spine density.
Hui Qiao   +5 more
semanticscholar   +1 more source

Dendritic spine pathology in schizophrenia [PDF]

open access: yesNeuroscience, 2013
Schizophrenia is a neurodevelopmental disorder whose clinical features include impairments in perception, cognition and motivation. These impairments reflect alterations in neuronal circuitry within and across multiple brain regions that are due, at least in part, to deficits in dendritic spines, the site of most excitatory synaptic connections ...
David A. Lewis, Jill R. Glausier
openaire   +3 more sources

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