Results 91 to 100 of about 23,901 (228)

Algorithm for Surgical Management in Patients in Treatment With Medication Associated With Osteonecrosis of the Jaws

Oral Surgery, EarlyView.
ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra, Gómez Hernández Kevin Andrew, Cabrera del Cid María Fernanda, Jerez Robalino James Philippe   +3 more
wiley   +1 more source

Denosumab, a RANK ligand inhibitor, for the management of bone loss in cancer patients

, 2012
Andrew J Yee, Noopur S RajeDivision of Hematology-Oncology, Massachusetts General Hospital Cancer Center, Boston, MA, USAAbstract: Bone loss is a common side effect of cancer treatments, especially antihormonal treatments used in the treatment of breast ...
Raje NS, Yee AJ
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Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

Orthopaedic Surgery, EarlyView.
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Xiang Yao, Yicong Chao, Xiao Gu, Jingtao Peng, Jishan Yuan, Wei Shi, Fuguo Zhang, Qiwen Bao   +7 more
wiley   +1 more source

Osteogenesis Imperfecta: A Review of Denosumab Research

, 2020
This article reviews the emerging literature on the efficacy of denosumab as a treatment for patients with Osteogenesis Imperfecta (OI). Denosumab improves bone density in adults with osteoporosis.
Kopplin, Echo L
core   +1 more source

Factors affecting the efficacy of nonsurgical therapy of peri‐implantitis

Periodontology 2000, EarlyView.
Abstract Objectives and Materials and Methods This article critically reviews the current knowledge on the factors influencing the efficacy of non‐surgical therapy (NST) of peri‐implantitis, taking also advantage of the know‐how from periodontitis management.
Elena Calciolari, Federico Rivara, Nikolaos Donos, Jérôme F. Lasserre, Selena Toma   +4 more
wiley   +1 more source

High bone turnover elevates the risk of denosumab-induced hypocalcemia in women with postmenopausal osteoporosis

, 2016
Koji Ishikawa,1 Takashi Nagai,1 Keizo Sakamoto,1 Kenji Ohara,2 Takeshi Eguro,1,2 Hiroshi Ito,1 Yoichi Toyoshima,1 Akatsuki Kokaze,3 Tomoaki Toyone,1 Katsunori Inagaki1 1Department of Orthopaedic Surgery, Showa University School of Medicine, Tokyo ...
Ohara K, Inagaki K, Eguro T, Kokaze A, Nagai T, Sakamoto K, Ito H, Ishikawa K, Toyoshima Y, Toyone T   +9 more
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Shared molecular framework and bidirectional effects of osteoporosis on periodontal disease and dental implant therapy in the elderly

Periodontology 2000, EarlyView.
Abstract Objectives This review synthesizes evidence regarding the prevalence, epidemiological associations, and mechanistic pathways between osteoporosis, periodontal disease, and dental implant therapy. Materials and Methods A literature review was conducted to identify studies focused on: osteoporosis, periodontal disease, and dental implants ...
Samin Sirous, Jaclyn C. Chalmers, Pin‐Ying Li, Yumna Subhani, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Denosumab as Second-Line Treatment in Patients With Metastatic Breast Cancer: A Retrospective Descriptive Pilot Study From a Single Institution

Cancer Control
Introduction Bone metastasis in breast cancer patients can lead to poor quality of life and cause significant morbidity. First-line treatments for bone metastases include bone modifying agents that inhibit osteoclast activity to reduce bone resorption ...
Briana To, Laura E. Wright, Dureti Doto, Julie Stephans, Marilly Palettas, Kai C. Johnson, Mathew Cherian, Daniel Stover, Ashley Davenport, Margaret Gatti-Mays, Robert Wesolowski, Dionisia Quiroga, Sagar Sardesai, Gilbert Bader, Bhuvaneswari Ramaswamy, Nicole Williams   +15 more
doaj   +1 more source

Denosumab cessation [PDF]

Cleveland Clinic Journal of Medicine, 2020
openaire   +2 more sources

Impact of denosumab on bone mass in cancer patients

, 2013
Ursa Brown-Glaberman, Alison T StopeckUniversity of Arizona Cancer Center, Tucson, AZ, USAAbstract: Cancer therapy-induced bone loss (CTIBL) is a form of secondary osteoporosis associated with systemic chemotherapy and hormonal ablation therapy.
Stopeck AT, Brown-Glaberman U
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