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Acute Protoporphyric Hepatopathy as the Initial Presentation of Erythropoietic Protoporphyria in Adulthood. [PDF]
ACG Case Rep JAlsaleh T +3 more
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New England Journal of Medicine, 2014
To the Editor: Dense-deposit disease is a complement-mediated disorder characterized by a proliferative glomerulonephritis, bright capillary-wall C3 staining on immunofluorescence microscopy, and large intramembranous osmiophilic dense deposits that markedly thicken the glomerular capillary walls.1,2 The underlying pathophysiology — fluid-phase ...
Sanjeev Sethi +2 more
exaly +7 more sources
To the Editor: Dense-deposit disease is a complement-mediated disorder characterized by a proliferative glomerulonephritis, bright capillary-wall C3 staining on immunofluorescence microscopy, and large intramembranous osmiophilic dense deposits that markedly thicken the glomerular capillary walls.1,2 The underlying pathophysiology — fluid-phase ...
Sanjeev Sethi +2 more
exaly +7 more sources
Eculizumab in a Patient with Dense-Deposit Disease
New England Journal of Medicine, 2012This letter indicates that in a patient with long-standing dense-deposit disease, a variant of membranoproliferative glomerulonephritis, eculizumab can be useful in the resolution of the nephrotic syndrome.
E. Daina, M. Noris, G. Remuzzi
openaire +3 more sources
Dense deposit disease associated with multiple myeloma
Clinical Nephrology, 2018Dense deposit disease (DDD) is a very rare pathological finding associated with activation of the final complement pathway. DDD has been rarely found in association with multiple myeloma (MM). Here we report a patient with MM presenting with renal failure, anemia, and bone pain. The renal biopsy showed DDD.
Ahmed M, Alkhunaizi +3 more
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Dense deposit disease: new insights
Current Opinion in Nephrology and Hypertension, 2007Dense deposit disease is a rare but devastating disease primarily affecting children. This review focuses on new information regarding the pathophysiology of dense deposit disease, its appearance histopathologically, its relationship to other diseases including macular degeneration and acquired partial lipodystrophy and potential new therapies.The ...
openaire +2 more sources
Spontaneous clinical improvement in dense deposit disease
Pediatric Nephrology, 2000The clinical course and 3-year follow-up of a female patient aged 11 years who presented with nephrotic syndrome and renal failure is described. The renal biopsy revealed type II membranoproliferative glomerulonephritis or dense deposit disease. She was treated with penicillin prophylaxis, frusemide and captopril, and was not given immunosuppression ...
S D, Marks, L, Rees
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Recurrent dense deposit disease in renal allograft
Urology, 1978This report documents the recurrence of dense deposit disease in a renal allograft thirty-three days post-transplantation and stresses the usefulness of immunofluorescence in early detection.
A F, Jukkola +3 more
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APMIS, 1993
A membranoproliferative glomerulonephritis (MPGN) was diagnosed in 10 Yorkshire piglets, aged between 33 and 73 days, that had been submitted for routine autopsy. Matings of animals related to these piglets subsequently produced 15 offspring that had a membranoproliferative glomerulonephritis when examined at between 5 and 48 days of age. The principal
openaire +2 more sources
A membranoproliferative glomerulonephritis (MPGN) was diagnosed in 10 Yorkshire piglets, aged between 33 and 73 days, that had been submitted for routine autopsy. Matings of animals related to these piglets subsequently produced 15 offspring that had a membranoproliferative glomerulonephritis when examined at between 5 and 48 days of age. The principal
openaire +2 more sources