Results 91 to 100 of about 61,176 (239)

Thioperamide-induced Antinociception is Mediated through Endogenous Opioid System in the Dentate Gyrus of Adult Rats [PDF]

open access: yesVeterinary Research Forum, 2010
The present study investigated the effects of intra-dentate gyrus microinjection of naloxone (an opioid antagonist) and thioperamide (an antagonist of histamine H3 receptors) in the formalin test in rats. Subcutaneous injection of formalin (50 µl, 2.5 %)
Emad Khalilzadeh   +3 more
doaj  

The enigmatic mossy cell of the dentate gyrus [PDF]

open access: yesNature Reviews Neuroscience, 2016
Mossy cells comprise a large fraction of the cells in the hippocampal dentate gyrus, suggesting that their function in this region is important. They are vulnerable to ischaemia, traumatic brain injury and seizures, and their loss could contribute to dentate gyrus dysfunction in such conditions.
openaire   +3 more sources

Identifying Brain Image Level Endophenotypes in Epilepsy [PDF]

open access: yesarXiv, 2012
A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with epilepsy are those bilateral links with regions mainly belonging to the default mode network and subcortex, such ...
arxiv  

Activation of hypoactive parvalbumin-positive fast-spiking interneurons restores dentate inhibition to reduce electrographic seizures in the mouse intrahippocampal kainate model of temporal lobe epilepsy

open access: yesNeurobiology of Disease
Parvalbumin-positive (PV+) GABAergic interneurons in the dentate gyrus provide powerful perisomatic inhibition of dentate granule cells (DGCs) to prevent overexcitation and maintain the stability of dentate gyrus circuits.
Sang-Hun Lee   +2 more
doaj  

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