Results 91 to 100 of about 63,053 (291)

Object-Place Recognition Learning Triggers Rapid Induction of Plasticity-Related Immediate Early Genes and Synaptic Proteins in the Rat Dentate Gyrus

open access: yesNeural Plasticity, 2008
Long-term recognition memory requires protein synthesis, but little is known about the coordinate regulation of specific genes. Here, we examined expression of the plasticity-associated immediate early genes (Arc, Zif268, and Narp) in the dentate gyrus ...
Jonathan Soulé   +5 more
doaj   +1 more source

Toward a full-scale computational model of the rat dentate gyrus

open access: yesFrontiers in Neural Circuits, 2012
Recent advances in parallel computing, including the creation of the parallel version of the NEURON simulation environment, have allowed for a previously unattainable level of complexity and detail in neural network models.
Calvin James Schneider   +2 more
doaj   +1 more source

Extrinsic afferent systems to the dentate gyrus [PDF]

open access: yes, 2007
The dentate gyrus is the first stage of the intrahippocampal, excitatory, trisynaptic loop, and a primary target of the majority of entorhinal afferents that terminate in a laminar fashion on granule cell dendrites and carry sensory information of multiple modalities about the external world.
Tibor Hajszan   +2 more
openaire   +3 more sources

Deficiency of nNOS in adult‐born dentate granule cells causes epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective This study aimed to elucidate the molecular role of neuronal nitric oxide synthase (nNOS, encoded by Nos1) in adult‐born dentate granule cells (DGCs) during temporal lobe epilepsy (TLE). Methods We used GFP‐expressing retrovirus (RV) to analyze morphological changes in DGCs.
Hanyu Huang   +11 more
wiley   +1 more source

Thioperamide-induced Antinociception is Mediated through Endogenous Opioid System in the Dentate Gyrus of Adult Rats [PDF]

open access: yesVeterinary Research Forum, 2010
The present study investigated the effects of intra-dentate gyrus microinjection of naloxone (an opioid antagonist) and thioperamide (an antagonist of histamine H3 receptors) in the formalin test in rats. Subcutaneous injection of formalin (50 µl, 2.5 %)
Emad Khalilzadeh   +3 more
doaj  

The enigmatic mossy cell of the dentate gyrus [PDF]

open access: yesNature Reviews Neuroscience, 2016
Mossy cells comprise a large fraction of the cells in the hippocampal dentate gyrus, suggesting that their function in this region is important. They are vulnerable to ischaemia, traumatic brain injury and seizures, and their loss could contribute to dentate gyrus dysfunction in such conditions.
openaire   +3 more sources

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

open access: yesIbrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

Effect of interaventricular injection of Vitamin C on the histological structural of dentate gyrus of hipocampus in epileptic rats

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2016
Background and Objective: Hippocampus is the main region in cortex of the brain that involved in epilepsy. This study was done to determine the effect of intraventricular injection of vitamin C on histological structure of dentate gyrus of hipocampus in ...
R Golmohammadi, B Kmalimansh
doaj  

The mechanisms in glucose metabolism of aging hippocampus

open access: yesIbrain, EarlyView.
Cognitive decline in elders stems from the irreversible loss and functional decline of neurons, with the hippocampus being particularly susceptible to age‐related neuronal deterioration. Glucose acts as the primary fuel for the brain, and a constant provision of glucose to the hippocampus is essential for memory and cognitive functions.
Rui He   +6 more
wiley   +1 more source

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