Results 91 to 100 of about 131,553 (328)
What is the functional role of adult neurogenesis in the hippocampus? [PDF]
The dentate gyrus is part of the hippocampal memory system and special in that it generates new neurons throughout life. Here we discuss the question of what the functional role of these new neurons might be.
Kempermann, Gerd+2 more
core +1 more source
Rapid erasure of hippocampal memory following inhibition of dentate gyrus granule cells
The hippocampus is critical for the acquisition and retrieval of episodic and contextual memories. Lesions of the dentate gyrus, a principal input of the hippocampus, block memory acquisition, but it remains unclear whether this region also plays a role ...
N. Madroñal+11 more
semanticscholar +1 more source
Objectives Prospective studies demonstrated that essential tremor is a risk factor for Parkinson's disease. Identifying clinical markers for conversion from essential tremor to essential tremor‐Parkinson's disease would be of considerable value. Rest tremor can be present in advanced essential tremor and may be a harbinger of conversion. We examined (1)
Elan D. Louis+3 more
wiley +1 more source
There is growing evidence from epidemiological studies that especially midlife physical activity might exert a positive influence on the risk and progression of Alzheimer’s disease.
Anna-Lina Gerberding+4 more
doaj +1 more source
Reelin Mediates Hippocampal Cajal-Retzius Cell Positioning and Infrapyramidal Blade Morphogenesis
We have previously described hypomorphic reelin (Reln) mutant mice, RelnCTRdel, in which the morphology of the dentate gyrus is distinct from that seen in reeler mice.
Seungshin Ha+4 more
doaj +1 more source
Cortistain is expressed in a distinct subset of cortical interneurons [PDF]
Cortistatin is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin. In contrast to somatostatin, administration of cortistatin into the rat brain ventricles specifically enhances slow wave sleep, apparently by antagonizing ...
Alcántara Horrillo, Soledad+8 more
core
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek+5 more
wiley +1 more source
Recognition Memory Dysfunction Relates to Hippocampal Subfield Volume: A Study of Cognitively Normal and Mildly Impaired Older Adults. [PDF]
ObjectivesThe current study examined recognition memory dysfunction and its neuroanatomical substrates in cognitively normal older adults and those diagnosed with mild cognitive impairment (MCI).MethodsParticipants completed the Mnemonic Similarity Task,
Bennett, Ilana J+2 more
core +2 more sources
The CA3 “backprojection” to the dentate gyrus [PDF]
The hippocampus is typically described in the context of the trisynaptic circuit, a pathway that relays information from the perforant path to the dentate gyrus, dentate to area CA3, and CA3 to area CA1. Associated with this concept is the assumption that most hippocampal information processing occurs along the trisynaptic circuit.
openaire +3 more sources
Dentate gyrus and hilar region revisited [PDF]
AbstractIt is suggested that the dentate gyrus and hilar region in the hippocampus perform memory selection and that the selectivity of the gating of memory by this circuit is modulated by the norepinephrine–glutamate loop described by Mather et al.
openaire +5 more sources