Results 141 to 150 of about 63,053 (291)
Opioid Modulation of Recurrent Excitation in the Hippocampal Dentate Gyrus [PDF]
Gregory W. Terman+4 more
openalex +1 more source
Topiramate for the treatment of neonatal seizures and beyond
Abstract Acute symptomatic neonatal seizures are one of the most common neurological disorders in newborns admitted to neonatal intensive care units and require prompt treatment. Up to 50% of neonatal seizures are refractory to first‐line medications such as phenobarbital (PB), and another 30% fail second‐line therapy.
Wolfgang Löscher, Janet S. Soul
wiley +1 more source
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti+14 more
wiley +1 more source
Rapid Signaling at Inhibitory Synapses in a Dentate Gyrus Interneuron Network [PDF]
Marlene Bartos+4 more
openalex +1 more source
Abstract Objective Fibroblast growth factor 12 (FGF12), a member of the fibroblast homologous factor family, plays a key role in the modulation of voltage‐gated sodium (Nav) channels. Pathogenic variants in the FGF12 gene leading to a gain‐of‐function mechanism and partial duplication encompassing the FGF12 gene leading to a loss‐of‐function mechanism ...
Jade Fauqueux+18 more
wiley +1 more source
Long-term plasticity in interneurons of the dentate gyrus [PDF]
Stephen T. Ross, Iván Soltész
openalex +1 more source
Novel neuropathological observations in an adult with Dravet syndrome
Abstract Dravet syndrome (DS) is a developmental and epileptic encephalopathy associated with pathogenic variants in the SCN1A gene. The neuropathological features of adult DS remain poorly understood. We report the postmortem findings of a 55‐year‐old woman with DS due to a confirmed SCN1A pathogenic variant leading to Nav1.1 loss of function ...
Danielle M. Andrade+7 more
wiley +1 more source
Dentate Gyrus and CA1 Ensemble Activity during Spatial Reference Frame Shifts in the Presence and Absence of Visual Input [PDF]
Katalin M. Gothard+3 more
openalex +1 more source