Results 141 to 150 of about 131,553 (328)
Effects of nicotine administration on amyloid precursor protein metabolism, neural cell genesis and acquisition of spatial memory [PDF]
, 2011 Nicotine is reported to improve learning and memory in experimental animals. Improved learning and memory has also been related to increased neural cell genesis in the dentate gyrus of the brain hippocampal formation.
Scerri, Charles
core
Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy [PDF]
, 2010 High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone.
Cmejla, Roman +5 more
core +3 more sources
Proteomic Profiling of the Epileptic Dentate Gyrus
Brain Pathology, 2010 AbstractThe development of epilepsy is often associated with marked changes in central nervous system cell structure and function. Along these lines, reactive gliosis and granule cell axonal sprouting within the dentate gyrus of the hippocampus are commonly observed in individuals with temporal lobe epilepsy (TLE). Here we used the pilocarpine model of
Aiqing Li +6 more
openaire +4 more sources
Journal of Biophotonics, EarlyView.Photobiomodulation (808 nm laser, optimized at 80 Hz, 30% duty cycle) significantly enhances mitochondrial function, reduces β‐amyloid deposition, and attenuates microglial activation in a 5XFAD Alzheimer's mouse model. Delayed luminescence serves as a novel bioenergetic marker, linking improved mitochondrial efficiency to cognitive and ...
Hong Bae Kim, Chang Kyu Sung
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2016 Background and Objective: Hippocampus is the main region in cortex of the brain that involved in epilepsy. This study was done to determine the effect of intraventricular injection of vitamin C on histological structure of dentate gyrus of hipocampus in ...
R Golmohammadi, B Kmalimansh
doaj
Thioperamide-induced Antinociception is Mediated through Endogenous Opioid System in the Dentate Gyrus of Adult Rats [PDF]
Veterinary Research Forum, 2010 The present study investigated the effects of intra-dentate gyrus microinjection of naloxone (an opioid antagonist) and thioperamide (an antagonist of histamine H3 receptors) in the formalin test in rats. Subcutaneous injection of formalin (50 µl, 2.5 %)
Emad Khalilzadeh +3 more
doaj
Movement Disorders, EarlyView.ABSTRACT Neuroimaging with positron emission tomography (PET) has been instrumental in elucidating neurobiological mechanisms behind therapeutical trials in Parkinson's disease (PD). A variety of medical and neurosurgical interventions have been evaluated using many radioligands that reveal molecular basis for target engagement and brain responses in ...
Vijay Dhawan +4 more
wiley +1 more source
Nature and fate of proliferative cells in the hippocampal dentate gyrus during the life span of the rhesus monkey [PDF]
, 1988 MF Eckenhoff, Pasko Rakić
openalex +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Targeting tauopathy with engineered tau-degrading intrabodies [PDF]
, 2019 BACKGROUND: The accumulation of pathological tau is the main component of neurofibrillary tangles and other tau aggregates in several neurodegenerative diseases, referred to as tauopathies.
Gallardo, Gilbert +7 more
core +1 more source