Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Clozapine Prevents a Decrease in Neurogenesis in Mice Repeatedly Treated With Phencyclidine
Journal of Pharmacological Sciences, 2007 It has recently been suggested that neurogenesis in the dentate gyrus is decreased in schizophrenia and this phenomenon may contribute to the pathogenesis of the disorder.
Kenji Maeda +7 more
doaj +1 more source
Clock gene dysregulation in epilepsy: A systematic review
Epilepsia Open, EarlyView.Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos +3 more
wiley +1 more source
Exploring adult hippocampal neurogenesis using optogenetics [PDF]
, 2018 In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core
Neuroanatomical and functional correlates in borderline personality disorder: A narrative review
Ibrain, Volume 11, Issue 1, Page 19-31, Spring 2025.Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley +1 more source
Transformation of spatial representations along hippocampal circuits
iScienceSummary: The hippocampus is thought to provide the brain with a cognitive map of the external world by processing various types of spatial information.
Bérénice Gandit +6 more
doaj +1 more source
Disparate forms of heterogeneities and interactions among them drive channel decorrelation in the dentate gyrus: Degeneracy and dominance [PDF]
, 2018 Poonam Mishra, Rishikesh Narayanan
openalex +1 more source
Moderate effect of early-life experience on dentate gyrus function [PDF]
, 2022 Pacifique Rukundo +3 more
openalex +1 more source
Preoperative Functional Connectivity Predicts Antiparkinson Drug Change after Deep Brain Stimulation
Movement Disorders, EarlyView.Abstract Background Deep brain stimulation (DBS) can effectively ameliorate motor symptoms in Parkinson's disease (PD), but patient outcomes remain variable. Clinical predictors lack reliability and only explain a small proportion of outcome variance, outlining a need for biomarkers that can enhance prediction accuracy.
David Mikhael +9 more
wiley +1 more source
Sensory sensitivity as a link between concussive traumatic brain injury and PTSD. [PDF]
, 2019 Traumatic brain injury (TBI) is one of the most common injuries to military personnel, a population often exposed to stressful stimuli and emotional trauma.
Fanselow, Michael S +4 more
core +1 more source