Results 201 to 210 of about 63,053 (291)

Long‐Term Memory Engrams From Development to Adulthood

open access: yesHippocampus, Volume 35, Issue 5, September 2025.
ABSTRACT Memories formed in adulthood can last a lifetime, whereas those formed early in life are rapidly forgotten through a process known as infantile amnesia. In recent years, tremendous progress has been made in understanding the memory engram—the physical trace of a memory in the brain—and how it transforms as memories evolve from recent to remote.
Abigail L. Yu, Laura A. DeNardo
wiley   +1 more source

Activity and Heterogeneity of Astrocytes in Neurological Diseases: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Astrocytes display heterogeneity in various neurological disorders and behavioral neuropsychiatric disorders. Astrocytes influence the progression of neurological diseases through neuroinflammation, oxidative stress, metabolic abnormalities, intercellular interactions, and a spectrum of other pathophysiological processes.
Shijie Mao   +12 more
wiley   +1 more source

Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer's disease. [PDF]

open access: yesAlzheimers Res Ther
Alcantara-Gonzalez D   +4 more
europepmc   +1 more source

Mitochondrial Dysfunction in Aging: Future Therapies and Precision Medicine Approaches

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
Mitochondria play a critical role in aging and aging‐related diseases. This review systematically explores the mechanisms underlying mitochondrial deterioration during aging and highlights innovative therapeutic strategies for these mitochondrial problems.
Lanlan Jia   +4 more
wiley   +1 more source

Diversification of dentate gyrus granule cell subtypes is regulated by Nrg1 nuclear back-signaling. [PDF]

open access: yesLife Sci Alliance
Rajebhosale P   +7 more
europepmc   +1 more source

Quantitative susceptibility mapping in magnetically inhomogeneous tissues

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 3, Page 1044-1059, September 2025.
Abstract Purpose Conventional quantitative susceptibility mapping (QSM) methods rely on simplified physical models that assume isotropic and homogeneous tissue properties, leading to artifacts and inaccuracies in biological tissues. This study aims to develop and evaluate DEEPOLE, a deep learning–based method that incorporates macroscopically ...
Thomas Jochmann   +6 more
wiley   +1 more source

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