Results 81 to 90 of about 131,553 (328)

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

In Vivo and In Vitro Treatment With Edaravone Promotes Proliferation of Neural Progenitor Cells Generated Following Neuronal Loss in the Mouse Dentate Gyrus

Journal of Pharmacological Sciences, 2013
Edaravone is clinically used in Japan for treatment of patients with acute cerebral infarction. To clarify the effect of edaravone on neurogenesis in the hippocampus following neuronal injury in the hippocampal dentate gyrus, we investigated the effect ...
Maho Kikuta, Tatsuo Shiba, Masanori Yoneyama, Koichi Kawada, Taro Yamaguchi, Eiichi Hinoi, Yukio Yoneda, Kiyokazu Ogita   +7 more
doaj  

Computational Pattern Separation Models of Dentate Gyrus Neural Subpopulation in the Hippocampus

Caspian Journal of Neurological Sciences, 2022
Hippocampus is a part of the brain that has an essential role in memory and learning. It is involved in many cognitive and behavioral phenomena, including the pattern separation process: the ability to distinguish patterns with very high similarity.
Nazal Modhej, Azam Bastanfard, Mohammad Teshnehlab, Somayeh Raiesdana   +3 more
doaj  

The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory

Scientific Reports, 2017
Both recognition of familiar objects and pattern separation, a process that orthogonalises overlapping events, are critical for effective memory. Evidence is emerging that human pattern separation requires dentate gyrus.
Serena Dillon, Demitra Tsivos, Michael Knight, Bryony McCann, Catherine M Pennington, A. Shiel, Myra E. Conway, M. Newson, Risto A. Kauppinen, Elizabeth J Coulthard   +9 more
semanticscholar   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Hippocampus and dentate gyrus morphological сhanges in posterity of female rats after receiving PgE2 for labor induction.

Морфологія, 2019
Background. The effect of labor stimulation on the brain structure still remains an unexplored issue. Objective. To determine the morphological hippocampus and dentate gyrus changes in laboratory rats on the first day of life after intravaginal injection
E. A. Hrygorieva, I. Y. Mamay
doaj   +1 more source

Adiponectin Exerts Neurotrophic Effects on Dendritic Arborization, Spinogenesis, and Neurogenesis of the Dentate Gyrus of Male Mice.

Endocrinology, 2016
The hippocampus, a brain region critical for learning, memory and emotional processing, maintains its capacity to undergo structural plasticity throughout life.
Di Zhang, Xuezhen Wang, Xin-Yun Lu
semanticscholar   +1 more source

Regional and Global Changes in Brain Structure 1‐Year Post Pediatric “Mild” Traumatic Brain Injury

Annals of Neurology, EarlyView.
Objective Despite the high prevalence of pediatric “mild” traumatic brain injury (pmTBI), very little is known about the long‐term effects of injury on brain structure and how injuries manifest in the context of dynamic and regionally specific neurodevelopmental changes. Methods Prospective study design characterizing long‐term effects of pmTBI on both
Upasana Nathaniel, Tracey V. Wick, Josef L. Ling, Jessica R. McQuaid, Divyasree Sasi Kumar, Samuel D. Miller, Jingshu Wu, Vadim Zotev, Timothy B. Meier, Harm J. van der Horn, John P. Phillips, Richard A. Campbell, Robert E. Sapien, Rahsan Keskin, Andrei A. Vakhtin, Andrew R. Mayer   +15 more
wiley   +1 more source

Beneficial In Vivo Effect of Aripiprazole on Neuronal Regeneration Following Neuronal Loss in the Dentate Gyrus: Evaluation Using a Mouse Model of Trimethyltin-Induced Neuronal Loss/Self-Repair in the Dentate Gyrus

Journal of Pharmacological Sciences, 2014
.: Aripiprazole is used clinically as an atypical antipsychotic. We evaluated the effect of in vivo treatment with aripiprazole on the proliferation and differentiation of neural stem/progenitor cells in a mouse model, trimethyltin-induced neuronal loss ...
Masanori Yoneyama, Shigeru Hasebe, Noriko Kawamoto, Tatsuo Shiba, Taro Yamaguchi, Maho Kikuta, Makoto Shuto, Kiyokazu Ogita   +7 more
doaj  

Status epilepticus induced Gadd45b is required for augmented dentate neurogenesis

Stem Cell Research, 2020
In animal models with temporal lobe epilepsy (TLE), the status epilepticus (SE) leads to a dramatic increase in number of newly born neuron in the subgranular zone (SGZ) of dentate gyrus.
Xin-Li Xiao, Xiao-Lin Wu, Peng-Bo Yang, Hai-Bo Hu, Yu Chen, Min-Li, Kai-Wei Si, Feng Wu, Jian-Xin Liu   +8 more
doaj