Neurogenesis-Inspired Dictionary Learning: Online Model Adaption in a Changing World [PDF]
In this paper, we focus on online representation learning in non-stationary environments which may require continuous adaptation of model architecture. We propose a novel online dictionary-learning (sparse-coding) framework which incorporates the addition and deletion of hidden units (dictionary elements), and is inspired by the adult neurogenesis ...
arxiv
Neurogenesis and multiple plasticity mechanisms enhance associative memory retrieval in a spiking network model of the hippocampus [PDF]
Hippocampal CA3 is crucial for the formation of long-term associative memory. It has a heavily recurrent connectivity, and memories are thought to be stored as memory engrams in the CA3. However, despite its importance for memory storage and retrieval, spiking network models of the CA3 to date are relatively small-scale, and exist as only proof-of ...
arxiv
The Dentate Gyrus: Its Value for Depression [PDF]
Jasper O. Nuninga, Iris E.C. Sommer
openaire +3 more sources
Temporary changes in large-scale memory neural networks after fear learning and extinction in healthy adults [PDF]
The analysis of the functional connectivity of brain sections associated with fear-conditioned training is one of the methods of study of memory neural networks. Before, the majority of studies focused on the functional connectivity of the brain regions that are known for emotional processing such as amygdala and areas of the ventromedial prefrontal ...
arxiv
Clonal analysis of newborn hippocampal dentate granule cell proliferation and development in temporal lobe epilepsy [PDF]
Hippocampal dentate granule cells are among the few neuronal cell types generated throughout adult life in mammals. In the normal brain, new granule cells are generated from progenitors in the subgranular zone and integrate in a typical fashion. During the development of epilepsy, granule cell integration is profoundly altered. The new cells migrate to
arxiv
Neural Modulation Alteration to Positive and Negative Emotions in Depressed Patients: Insights from fMRI Using Positive/Negative Emotion Atlas [PDF]
Background: Although it has been noticed that depressed patients show differences in processing emotions, the precise neural modulation mechanisms of positive and negative emotions remain elusive. FMRI is a cutting-edge medical imaging technology renowned for its high spatial resolution and dynamic temporal information, making it particularly suitable ...
arxiv +1 more source
Proteomic Profiling of the Epileptic Dentate Gyrus
AbstractThe development of epilepsy is often associated with marked changes in central nervous system cell structure and function. Along these lines, reactive gliosis and granule cell axonal sprouting within the dentate gyrus of the hippocampus are commonly observed in individuals with temporal lobe epilepsy (TLE). Here we used the pilocarpine model of
Aiqing Li+6 more
openaire +4 more sources
Extrinsic afferent systems to the dentate gyrus [PDF]
The dentate gyrus is the first stage of the intrahippocampal, excitatory, trisynaptic loop, and a primary target of the majority of entorhinal afferents that terminate in a laminar fashion on granule cell dendrites and carry sensory information of multiple modalities about the external world.
Tibor Hajszan+2 more
openaire +3 more sources
Background and Objective: Hippocampus is the main region in cortex of the brain that involved in epilepsy. This study was done to determine the effect of intraventricular injection of vitamin C on histological structure of dentate gyrus of hipocampus in ...
R Golmohammadi, B Kmalimansh
doaj
Toward a full-scale computational model of the rat dentate gyrus
Recent advances in parallel computing, including the creation of the parallel version of the NEURON simulation environment, have allowed for a previously unattainable level of complexity and detail in neural network models.
Calvin James Schneider+2 more
doaj +1 more source