Results 11 to 20 of about 26,465 (179)

Glucose-Dependent Insulinotropic Polypeptide and Substance P Mediate Emetic Response Induction by Masked Trichothecene Deoxynivalenol-3-Glucoside through Ca²⁺ Signaling. [PDF]

Toxins (Basel), 2022
Deoxynivalenol (DON), the most naturally-occurring trichothecenes, may affect animal and human health by causing vomiting as a hallmark of food poisoning. Deoxynivalenol-3-glucoside (D3G) usually co-occurs with DON as its glucosylated form and is another
Qin Z, Zhang H, Wu Q, Wei B, Wu R, Guo X, Xiao H, Wu W.   +7 more
europepmc   +5 more sources

Humans significantly metabolize and excrete the mycotoxin deoxynivalenol and its modified form deoxynivalenol-3-glucoside within 24 hours. [PDF]

Sci Rep, 2018
For the first time, a comprehensive human intervention study was conducted to unravel the urinary excretion profile and metabolism of the fungal metabolite deoxynivalenol (DON) and its modified form deoxynivalenol-3-glucoside (DON-3-glucoside).
Vidal A, Claeys L, Mengelers M, Vanhoorne V, Vervaet C, Huybrechts B, De Saeger S, De Boevre M.   +7 more
europepmc   +9 more sources

Hydrolytic fate of deoxynivalenol-3-glucoside during digestion.

Toxicol Lett, 2011
Highlights ► Deoxynivalenol-3-glucoside (D3G) is hydrolyzed to deoxynivalenol during digestion. ► D3G is resistant to acids and enzymes expressed by humans. ► D3G is partly cleaved by cellulase and cellobiase.
Berthiller F, Krska R, Domig KJ, Kneifel W, Juge N, Schuhmacher R, Adam G.   +6 more
europepmc   +4 more sources

Metabolism of the masked mycotoxin deoxynivalenol-3-glucoside in pigs

Toxicology Letters, 2014
Plants can metabolize the Fusarium mycotoxin deoxynivalenol (DON) by forming the masked mycotoxin deoxynivalenol-3-β-D-glucoside (D3G). D3G might be cleaved during digestion, thus increasing the total DON burden of an individual. Due to a lack of in vivo
Veronika Nagl, Heidi Elisabeth Schwartz-Zimmermann, Isabel Hennig-Pauka   +2 more
exaly   +4 more sources

Simultaneous Determination of Deoxynivalenol, Deoxynivalenol-3-Glucoside and Nivalenol in Wheat Grains by HPLC-PDA with Immunoaffinity Column Cleanup [PDF]

Food Analytical Methods, 2016
Deoxynivalenol-3-glucoside (D3G) is a modified mycotoxin formed by the metabolism of plants through the conjugation of deoxynivalenol (DON) with glucose.
F. Trombete, A. Barros, Madalena Vieira, T. Saldanha, A. Venâncio, M. Fraga   +5 more
semanticscholar   +5 more sources

The human fecal microbiota metabolizes deoxynivalenol and deoxynivalenol-3-glucoside and may be responsible for urinary deepoxy-deoxynivalenol. [PDF]

Appl Environ Microbiol, 2013
ABSTRACT Deoxynivalenol (DON) is a potent mycotoxin produced by Fusarium molds and affects intestinal nutrient absorption and barrier function in experimental and farm animals. Free DON and the plant metabolite DON-3-β- d -glucoside (D3G) are frequently found in wheat and maize. D3G
Gratz SW, Duncan G, Richardson AJ.
europepmc   +5 more sources

Occurrence of Fusarium Mycotoxins and Their Modified Forms in Forage Maize Cultivars [PDF]

Toxins, 2021
Forage maize is often infected by mycotoxin-producing Fusarium fungi during plant growth, which represent a serious health risk to exposed animals. Deoxynivalenol (DON) and zearalenone (ZEN) are among the most important Fusarium mycotoxins, but little is
Tim Birr, Tolke Jensen, Nils Preußke, Frank D. Sönnichsen, Marthe De Boevre, Sarah De Saeger, Mario Hasler, Joseph-Alexander Verreet, Holger Klink   +8 more
doaj   +4 more sources

Concurrent Quantification of Deoxynivalenol, Its Derivatives, and Nivalenol in Pet Food Using QuEChERS Combined with LC-MS/MS [PDF]

Toxins
In the current research, we optimized a simultaneous method for quantifying deoxynivalenol (DON) and its derivative forms, deoxynivalenol-3-glucoside (D3G), 3-acetyl-deoxynivalenol (3-AcDON), 15-acetyl-deoxynivalenol (15-AcDON), and nivalenol (NIV), in ...
Chae-Eun Yeo, Subin Gwon, Eun Hee Chang, Hyo Young Kim, Sung-Youn Kim, Kangmin Seo, Ji Hye Lee, Hyunjeong Cho   +7 more
doaj   +2 more sources

Influence of Light Spectrum on Bread Wheat Head Colonization by Fusarium graminearum and on the Accumulation of Its Secondary Metabolites [PDF]

Plants
Previous studies indicated that light influences mycotoxin production and wheat’s defense responses to the cereal fungal pathogen Fusarium graminearum. Herein, the effect of different light wavelengths on F.
Minely Cerón-Bustamante, Francesco Tini, Giovanni Beccari, Andrea Onofri, Emilio Balducci, Michael Sulyok, Lorenzo Covarelli, Paolo Benincasa   +7 more
doaj   +2 more sources

Occurrence, Distribution Characteristics, Risk Assessment, and Climatic Drivers of Type B Trichothecenes and Their Transformation Products in Major Wheat-Producing Areas of China [PDF]

Toxins
Type B trichothecenes (B-TCTs), predominant mycotoxins in wheat, threaten human health. However, their contamination profile in China, a major wheat producer, remains unclear.
Jie Wang, Yu Wu, Di Cai, Li Li, Songshan Wang, Yu Zhang, Xiaomin Han, Songxue Wang, Leiqing Pan, Jin Ye   +9 more
doaj   +2 more sources