Results 31 to 40 of about 13,267,617 (166)

Occurrence, Distribution Characteristics, Risk Assessment, and Climatic Drivers of Type B Trichothecenes and Their Transformation Products in Major Wheat-Producing Areas of China [PDF]

Toxins
Type B trichothecenes (B-TCTs), predominant mycotoxins in wheat, threaten human health. However, their contamination profile in China, a major wheat producer, remains unclear.
Jie Wang, Yu Wu, Di Cai, Li Li, Songshan Wang, Yu Zhang, Xiaomin Han, Songxue Wang, Leiqing Pan, Jin Ye   +9 more
doaj   +2 more sources

Investigation of age-related differences in toxicokinetic processes of deoxynivalenol and deoxynivalenol-3-glucoside in weaned piglets

Archives of Toxicology, 2019
Age-related differences in toxicokinetic processes of deoxynivalenol (DON) and deoxynivalenol-3-glucoside (DON3G) were studied. DON3G [55.7 µg/kg bodyweight (BW)] and an equimolar dose of DON (36 µg/kg BW) were administered to weaned piglets (4 weeks old) by single intravenous and oral administration in a double two-way cross-over design.
Amelie Catteuw, Mathias Devreese, Siegrid De Baere, Gunther Antonissen, Lada Ivanova, Silvio Uhlig, Ann Martens, Sarah De Saeger, Marthe De Boevre, Siska Croubels   +9 more
openaire   +3 more sources

Fate of deoxynivalenol and deoxynivalenol-3-glucoside during cereal-based thermal food processing: a review study

Mycotoxin Research, 2016
Deoxynivalenol (DON), the most commonly occurring trichothecene in nature, may affect animal and human health through causing diarrhea, vomiting, gastrointestinal inflammation, and immunomodulation. DON-3-glucoside (DON-3G) as a major plant metabolite of the mycotoxin is another "emerging" food safety issue in recent years.
Qinghua, Wu, Kamil, Kuča, Hans-Ulrich, Humpf, Blanka, Klímová, Benedikt, Cramer   +4 more
core   +4 more sources

Plant-Derived UDP-Glycosyltransferases for Glycosylation-Mediated Detoxification of Deoxynivalenol: Enzyme Discovery, Characterization, and In Vivo Resistance Assessment [PDF]

Toxins
Fungal infections of crops pose a threat to global agriculture. Fungi of the genus Fusarium cause widespread diseases in cereal crops. Fusarium graminearum reduces yields and produces harmful mycotoxins such as deoxynivalenol (DON).
Valeria Della Gala, Laura Dato, Gerlinde Wiesenberger, Diana Jæger, Gerhard Adam, Jørgen Hansen, Ditte Hededam Welner   +6 more
doaj   +2 more sources

Glucose-Dependent Insulinotropic Polypeptide and Substance P Mediate Emetic Response Induction by Masked Trichothecene Deoxynivalenol-3-Glucoside through Ca²⁺ Signaling. [PDF]

Toxins (Basel), 2022
Deoxynivalenol (DON), the most naturally-occurring trichothecenes, may affect animal and human health by causing vomiting as a hallmark of food poisoning. Deoxynivalenol-3-glucoside (D3G) usually co-occurs with DON as its glucosylated form and is another emerging food safety issue in recent years.
Qin Z, Zhang H, Wu Q, Wei B, Wu R, Guo X, Xiao H, Wu W.   +7 more
europepmc   +4 more sources

Mapping Variability of Mycotoxins in Individual Oat Kernels from Batch Samples: Implications for Sampling and Food Safety [PDF]

Toxins
Oats are susceptible to contamination by Fusarium mycotoxins, including deoxynivalenol (DON), zearalenone (ZEN), and T-2/HT-2 toxins, posing food safety risks.
Irene Teixido-Orries, Francisco Molino, Bianca Castro-Criado, Monika Jodkowska, Angel Medina, Sonia Marín, Carol Verheecke-Vaessen   +6 more
doaj   +2 more sources

Survey of deoxynivalenol and deoxynivalenol-3-glucoside in cereal-based products by liquid chromatography electrospray ionization tandem mass spectrometry

World Mycotoxin Journal, 2011
It is well known that cereal crops exposed to deoxynivalenol (DON) infection are capable of detoxifying this mycotoxin through the plant metabolism. In this context, one major pathway is the conjugation of DON to a glucose moiety giving rise to 3-β-D-glucopyranosyl-4-deoxynivalenol (D3G).
A. Desmarchelier, W. Seefelder
openaire   +2 more sources

Effects of Durum Wheat Cultivars with Different Degrees of FHB Susceptibility Grown under Different Meteorological Conditions on the Contamination of Regulated, Modified and Emerging Mycotoxins

Microorganisms, 2021
The enhancement of Fusarium head blight (FHB) resistance is one of the best options to reduce mycotoxin contamination in wheat. This study has aimed to verify that the genotypes with high tolerance to deoxynivalenol could guarantee an overall ...
Valentina Scarpino, Massimo Blandino
doaj   +1 more source

The Role of Nitrogen Fertilization on the Occurrence of Regulated, Modified and Emerging Mycotoxins and Fungal Metabolites in Maize Kernels

Toxins, 2022
The European Food Safety Authority is currently evaluating the risks related to the presence of emerging mycotoxins in food and feeds. The aim of this study was to investigate the role of soil fertility, resulting from different nitrogen fertilization ...
Valentina Scarpino, Michael Sulyok, Rudolf Krska, Amedeo Reyneri, Massimo Blandino   +4 more
doaj   +1 more source

The human fecal microbiota metabolizes deoxynivalenol and deoxynivalenol-3-glucoside and may be responsible for urinary deepoxy-deoxynivalenol. [PDF]

Appl Environ Microbiol, 2013
ABSTRACT Deoxynivalenol (DON) is a potent mycotoxin produced by Fusarium molds and affects intestinal nutrient absorption and barrier function in experimental and farm animals. Free DON and the plant metabolite DON-3-β- d -glucoside (D3G) are frequently found in wheat and maize. D3G
Gratz SW, Duncan G, Richardson AJ.
europepmc   +4 more sources