Results 1 to 10 of about 10,903 (206)
Total Synthesis of the Marine Cyclic Depsipeptide Lagunamide D [PDF]
Marine DrugsLagunamide D is a structurally distinct 26-membered cytotoxic cyclic depsipeptide, originally isolated from a marine cyanobacterium. It exhibits potent antiproliferative activity in the low nanomolar range against A549 human lung adenocarcinoma cells and
Huiru Nan +8 more
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Clovibactin and Staphylococcus aureus: a new weapon against resistant strains [PDF]
GMS Hygiene and Infection ControlClovibactin is a new depsipeptide and highly efficacious against () , including methicillin-resistant and vancomycin-resistant , with no apparent resistance. Clovibactutclasses current antibiotics such as vancomycin.
Adeiza, Shuaibu Suleiman
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Morinagadepsin, a Depsipeptide from the Fungus Morinagamyces vermicularis gen. et comb. nov.
Microorganisms, 2021 The new genus Morinagamyces is introduced herein to accommodate the fungus Apiosordaria vermicularis as inferred from a phylogenetic study based on sequences of the internal transcribed spacer region (ITS), the nuclear rDNA large subunit (LSU), and ...
Karen Harms +4 more
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Nature Communications, 2021 FR900359 (FR) is a Gq protein inhibitor depsipeptide isolated from an uncultivable plant endosymbiont and synthesized by non-ribosomal peptide synthetases.
Cornelia Hermes +17 more
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Marine Drugs, 2021 Marine actinomycetes are prolific chemical sources of complex and novel natural products, providing an excellent chance for new drug discovery. The chemical investigation of the marine-derived Streptomyces sp.
Zhikai Guo +6 more
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Marine Organisms as a Prolific Source of Bioactive Depsipeptides
Marine Drugs, 2023 Depsipeptides, an important group of polypeptides containing residues of hydroxy acids and amino acids linked together by amide and ester bonds, have potential applications in agriculture and medicine.
Mingyuan Zeng +4 more
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A Survey of Didemnin Depsipeptide Production in Tistrella
Marine Drugs, 2023 As one of the first families of marine natural products to undergo clinical trials, the didemnin depsipeptides have played a significant role in inspiring the discovery of marine drugs.
Robert J. Stankey +4 more
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Frontiers in Catalysis, 2023 In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides.
Y. T. Candace Ho +28 more
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New Theonellapeptolides from Indonesian Marine Sponge Theonella swinhoei as Anti-Austerity Agents
Marine Drugs, 2022 We reported three new members of the theonellapeptolide family from theonellapeptolide II series, namely theonellapeptolides IIb (1), IIa (2), IIc (3), and three known members—IId (4), IIe (5), and Id (6)—from Kodingarengan marine sponge Theonella ...
Jabal Rahmat Haedar +4 more
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Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials
Molecules, 2023 Cancer is currently considered one of the most threatening diseases worldwide. Diet could be one of the factors that can be enhanced to comprehensively address a cancer patient’s condition.
Plinio A. Trinidad-Calderón +2 more
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