Results 51 to 60 of about 10,903 (206)
Pathogens, 2020 Fungi from the Hypocreales order synthesize a range of toxic non-ribosomal cyclic peptides with antimicrobial, insecticidal and cytotoxic activities. Entomopathogenic Beauveria, Isaria and Cordyceps as well as phytopathogenic Fusarium spp.
Monika Urbaniak +4 more
doaj +1 more source
Dithiolopyrrolone Natural Products : Isolation, Synthesis and Biosynthesis [PDF]
, 2013 Peer reviewedPublisher ...
Deng, Hai +3 more
core +2 more sources
MedComm, Volume 7, Issue 3, March 2026.Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
wiley +1 more source
Adsorption of cyclic depsipeptide mycotoxins to glass [PDF]
, 2014 During analytical processes, adsorption of peptides, which is believed to mostly be due to non-covalent interactions and depending upon the experimental conditions, cannot only lead to significant loss of the analyte, but also to increased analytical ...
De Spiegeleer, Bart +2 more
core +1 more source
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides
Journal of Peptide Science, Volume 32, Issue 3, March 2026.As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama +2 more
wiley +1 more source
Targeting Epigenetic Processes in Glioblastoma Mulitforme [PDF]
, 2007 Among tumors of the central nervous system, gliomas are the most prevalent and are associated with the poorest prognosis. Overall survival rates are low, and combined radioand chemo-therapy provides only marginal benefit; thus it is essential to ...
Earl, Christian
core
Histone deacetylase inhibitors – molecular mechanisms of actions and clinical applications [PDF]
, 2013 Histone deacetylases (HDACs) play an important role in the epigenetic regulation of gene expression implicated in cancer pathogenesis. Inhibitors of HDACs (HDI) are under investigation as novel anti-cancer drugs, which induce histone hyperacetylation ...
Andrzej Stepulak +3 more
core +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian +3 more
wiley +1 more source
Implication des modifications épigénétiques dans les cancers : développement de nouvelles approches thérapeutiques [PDF]
, 2008 Involvement of epigenetic modifications in cancers: development of new therapeutic approaches. Since cancer is the second cause of death after cardiovascular diseases in industrialized countries, it is urgent to elaborate new therapeutic approaches ...
Kettmann R., Vandermeers F., Willems L.
core
Total synthesis of Mycobacterium tuberculosis dideoxymycobactin-838 and stereoisomers: diverse CD1a-restricted T cells display a common hierarchy of lipopeptide recognition [PDF]
, 2016 Mycobacterium tuberculosis produces dideoxymycobactin-838 (DDM-838), a lipopeptide that potently activates T cells upon binding to the MHC-like antigen-presenting molecule CD1a. M.
Ando +28 more
core +4 more sources