Results 131 to 140 of about 2,772 (159)

Synthese geschützter Depsipeptide

Helvetica Chimica Acta, 1960
AbstractThe syntheses and properties of p‐nitrobenzyl diazoacetyl‐glycinate (VI), p‐nitrobenzyl p‐(p‐methoxyphenylazo)‐benzyloxycarbonyl‐glycyl‐glycollyl‐glycinate (II) and p‐nitrobenzyl p‐phenylazo‐benzyloxycarbonyl‐glycyl‐glycollyl‐glycinate are described. These compounds have been prepared as intermediates for the synthesis of other depsipeptides.
R. Schwyzer, J. P. Carrión
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Siamese Depsipeptides: Constrained Bicyclic Architectures

Angewandte Chemie, 2009
has been designed. Cyclic depsipeptide dimers connected by a CC bond were constructed. Two kind of possible connections can be envisaged, those that share a side chain bond or those that share a backbone bond. Owing to the resulting proximity of both structurally identical cycles, they can be called Siamese depsipeptides. For Siamese depsipeptides, the
Javier, Ruiz-Rodríguez, Jan, Spengler, Fernando, Albericio   +2 more
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Progress in Depsipeptide‐Based Biomaterials

Macromolecular Bioscience, 2010
AbstractPolydepsipeptides – alternating copolymers of an α‐amino acid and an α‐hydroxy acid – are a group of biodegradable polymers. Versatile polydepsipeptides with or without pendant functional groups, as well as various polymer architectures, for example, providing alternative, random, diblock, triblock, multiblock or graft sequence structures, can ...
Yakai, Feng, Jian, Lu, Marc, Behl, Andreas, Lendlein   +3 more
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Depsipeptides Communication 31. Synthesis of depsipeptides containing ?-hydroxy ?-amino acid residues

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1965
Depsipeptides containing α-hydroxy α-amino acid residues as hydroxy-acid component were synthesized.
G. A. Ravdel', N. A. Krit, V. A. Oladkina, L. A. Shchukina, M. M. Shemyakin   +4 more
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Depsipeptides from Metarhizium anisopliae

Phytochemistry, 1981
Abstract From the culture medium of a strain of Metarhizium anisopliae , 14 depsipeptides have been isolated. Five of them were identified as known destruxins A, B, C, D and desmethyldestruxin B. The structures of the new compounds, named destruxins E, A 1 , A 2 , B 1 , B 2 , C 2 , D 1 , D 2 and E 1 ,were established mainly from the mass spectral ...
Pais, M., Das, B.C., Ferron, P.
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Cyanopeptolins, depsipeptides from cyanobacteria

Systematic and Applied Microbiology, 1996
Summary The wide range of secondary metabolites from cyanobacteria includes cyclic depsipeptides. They can be filed into several classes. Members of class V, the cyanopeptolins, are proposed in this review to be defined as (a) cyanobacterial 19-membered cyclic depsipeptides cyclized by an ester-linkage of the hydroxyl-group of threonine with the ...
Jürgen Weckesser, Cornel Martin, Clemens Jakobi   +2 more
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Fungal cyclooligomer depsipeptides

Natural Product Reports, 2011
This review surveys the biological activities and the iterative and recursive biosynthetic mechanisms of fungal cyclooligomer depsipeptides, and their structural diversification by various combinatorial biosynthetic methods.
Süssmuth, Roderich, Müller, Jane, Von Döhren, Hans, Molnár, István   +3 more
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Total Synthesis of Antitumor Depsipeptide (−)-Doliculide

Organic Letters, 2001
[reaction: see text] (-)-Doliculide, a potent antitumor agent, is synthesized stereoselectively in a convergent manner. The key strategy involves a stereoselective synthesis of the polyketide unit and synthesis of the D-tyrosine derivative, followed by assembly of the fragments by an esterification and cycloamidation reaction sequence. The synthesis of
A K, Ghosh, C, Liu
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Cyclic depsipeptides as potential cancer therapeutics

Anti-Cancer Drugs, 2015
Cyclic depsipeptides are polypeptides in which one or more amino acid is replaced by a hydroxy acid, resulting in the formation of at least one ester bond in the core ring structure. Many natural cyclic depsipeptides possessing intriguing structural and biological properties, including antitumor, antifungal, antiviral, antibacterial, anthelmintic, and ...
Jirouta, Kitagaki, Genbin, Shi, Shizuka, Miyauchi, Shinya, Murakami, Yili, Yang   +4 more
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Biosynthesis of depsipeptide mycotoxins in Fusarium

European Journal of Plant Pathology, 2002
The cyclic hexadepsipeptide enniatin is known as a phytopathogenic compound from Fusaria causing necrosis and wilt. The molecule consists of three alternating residues each of a branched chain amino acid and D-hydroxyisovaleric acid (D-Hiv). Enniatins are synthesized by a 347kDa multienzyme (enniatin synthetase) via a thiol template mechanism.
Till Hornbogen, Mirko Glinski, Rainer Zocher   +2 more
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