Results 151 to 160 of about 3,874 (203)
Some of the next articles are maybe not open access.
ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maciej, Stawikowski, Predrag, Cudic
openaire +2 more sources
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maciej, Stawikowski, Predrag, Cudic
openaire +2 more sources
Antimitotic Peptides and Depsipeptides
Current Medicinal Chemistry-Anti-Cancer Agents, 2012Tubulin is the target for an ever increasing number of unusual peptides and depsipeptides that were originally isolated from a wide variety of organisms. Since tubulin is the major component of cellular microtubules, which maintain cell shape in interphase and form the mitotic spindle, most of these compounds are highly toxic to mammalian cells.
Ernest, Hamel, David G, Covell
openaire +2 more sources
Synlett, 2014 The enantioselective synthesis of the polyketide unit present in depsipeptides aetheramide A and B, which possess potent HIV-inhibitory activity, is accomplished from a chiral furyl ...
Kavirayani Prasad, Omkar Revu
exaly +2 more sources
Recent Developments in Depsipeptide Research
Current Medicinal Chemistry, 2002This review focuses on the major developments in depsipeptide research since 1995. Depsipeptides are bio-oligomers composed of hydroxy and amino acids linked by amide and ester bonds. Many depsipeptides show very promising biological activities, including anticancer, antibacterial, antiviral, antifungal, anti-inflammatory, and anti-clotting or anti ...
C E, Ballard, H, Yu, B, Wang
openaire +2 more sources
Biosynthesis of depsipeptide mycotoxins in Fusarium
European Journal of Plant Pathology, 2002The cyclic hexadepsipeptide enniatin is known as a phytopathogenic compound from Fusaria causing necrosis and wilt. The molecule consists of three alternating residues each of a branched chain amino acid and D-hydroxyisovaleric acid (D-Hiv). Enniatins are synthesized by a 347kDa multienzyme (enniatin synthetase) via a thiol template mechanism.
Till Hornbogen +2 more
openaire +1 more source
The structure-antimicrobial relation of depsipeptides
Experientia, 1963Die Beziehungen zwischen Struktur und antimikrobieller Aktivitat in der Reihe der Depsipeptide wurden untersucht. Cyclotetradepsipeptide sind praktisch inaktiv. Die grosste Aktivitat besitzen die Cyclohexadepsipeptide mit regularer Oxy- und Aminosaurensequenz.
M M, SHEMYARKIN +5 more
openaire +2 more sources
Progress in Depsipeptide‐Based Biomaterials
Macromolecular Bioscience, 2010AbstractPolydepsipeptides – alternating copolymers of an α‐amino acid and an α‐hydroxy acid – are a group of biodegradable polymers. Versatile polydepsipeptides with or without pendant functional groups, as well as various polymer architectures, for example, providing alternative, random, diblock, triblock, multiblock or graft sequence structures, can ...
Yakai, Feng +3 more
openaire +2 more sources
The Cyclic Depsipeptide Backbone of the Didemnins
Acta Crystallographica Section C Crystal Structure Communications, 1995An X-ray crystal analysis of phi-lactone N-¿1-¿N-¿4-¿[3- hydroxy-5-methyl-1-oxo-4-(N-L-threonylamino)heptyl]- oxy¿-2,5-dimethyl-1,3-dioxohexyl¿-L-leucyl¿-L-prolyl¿- N,O-dimethyl-L-tyrosine hydrobromide hydrate (1a), C42H66N5O11+.Br-.H2O, was obtained in order to determine the backbone folding of the macrocycle and to compare the results obtained with ...
S C, Mayer, P J, Carroll, M M, Joullié
openaire +2 more sources
Cyclic Depsipeptides, Callipeltins
2020Marine sponges are considered as an untapped reservoir of biologically active natural compounds exhibiting numerous interesting and potentially useful pharmacological activities, including antimicrobial, antifungal, cytotoxic, anti-inflammatory, and immunostimulatory activities.
Reda A. Abdelhamid, Hiroyuki Konno
openaire +1 more source
Synthese geschützter Depsipeptide
Helvetica Chimica Acta, 1960AbstractThe syntheses and properties of p‐nitrobenzyl diazoacetyl‐glycinate (VI), p‐nitrobenzyl p‐(p‐methoxyphenylazo)‐benzyloxycarbonyl‐glycyl‐glycollyl‐glycinate (II) and p‐nitrobenzyl p‐phenylazo‐benzyloxycarbonyl‐glycyl‐glycollyl‐glycinate are described. These compounds have been prepared as intermediates for the synthesis of other depsipeptides.
R. Schwyzer, J. P. Carrión
openaire +1 more source