Research and Application of Chondroitin Sulfate/Dermatan Sulfate-Degrading Enzymes [PDF]
Frontiers in Cell and Developmental Biology, 2020 Chondroitin sulfate (CS) and dermatan sulfate (DS) are widely distributed on the cell surface and in the extracellular matrix in the form of proteoglycan, where they participate in various biological processes.
Wenshuang Wang +3 more
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Sequencing the Dermatan Sulfate Chain of Decorin [PDF]
Journal of the American Chemical Society, 2017 Glycomics represents one of the last frontiers and most challenging in omic analysis. Glycosylation occurs in the endoplasmic reticulum and the Golgi organelle and its control is neither well-understood nor predictable based on proteomic or genomic analysis.
Kyohei Higashi +2 more
exaly +5 more sources
Data on cloning, expression and biochemical characteristics of a chondroitin sulfate/dermatan sulfate 4-O-endosulfatase [PDF]
Data in Brief, 2023 The data shown in this article are related to the published paper entitled “A novel 4-O-endosulfatase with high potential for the structure-function studies of chondroitin sulfate/dermatan sulfate” in Carbohydrate Polymers.
Lin Wei +9 more
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Dermatan Sulfate: Structure, Biosynthesis, and Biological Roles [PDF]
BiomoleculesDermatan sulfate (DS) is a remarkably versatile glycosaminoglycan that plays critical roles across a wide array of biological processes. Its unique structure, characterized by repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and Iduronic
Congcong Chen +7 more
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A Fluorescent Probe for Glycosaminoglycans Applied to the Detection of Dermatan Sulfate by a Mix-and-Read Assay [PDF]
Molecules, 2017 Glycosaminoglycans are complex biomolecules of great biological and medical importance. The quantification of glycosaminoglycans, in particular in complex matrices, is challenging due to their inherent structural heterogeneity.
Melissa Rappold +2 more
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Delineation of musculocontractural Ehlers–Danlos Syndrome caused by dermatan sulfate epimerase deficiency [PDF]
Molecular Genetics & Genomic Medicine, 2020 Background Musculocontractural Ehlers–Danlos Syndrome (mcEDS) is a rare connective tissue disorder caused by biallelic loss‐of‐function variants in CHST14 (mcEDS‐CHST14) or DSE (mcEDS‐DSE), both of which result in defective dermatan sulfate biosynthesis.
Charlotte K. Lautrup +12 more
doaj +2 more sources
Comparative Study of Two Chondroitin Sulfate/Dermatan Sulfate 4-O-Sulfatases With High Identity [PDF]
Frontiers in Microbiology, 2019 Chondroitin sulfate/dermatan sulfate (CS/DS) sulfatases are potential tools for structural and functional studies of CD/DS chains. In our previous study, a CS/DS 4-O-endosulfatase (endoVB4SF) was identified from a marine bacterium (Wang et al., 2015 ...
Shumin Wang +6 more
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Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders [PDF]
Pharmaceuticals, 2017 The indispensable roles of dermatan sulfate-proteoglycans (DS-PGs) have been demonstrated in various biological events including construction of the extracellular matrix and cell signaling through interactions with collagen and transforming growth factor-
Shuji Mizumoto +3 more
doaj +2 more sources
Data in support for the measurement of heparan sulfate and dermatan sulfate by LC–MS/MS analysis [PDF]
Data in Brief, 2018 This article provides supplementary data for the paper “LC–MS/MS method for simultaneous quantification of heparan sulfate and dermatan sulfate in urine by butanolysis derivatization” (Forni et al., 2018).
Giulia Forni +8 more
doaj +2 more sources
Evaluating Chondroitin Sulfate and Dermatan Sulfate Expression in Glial Scar to Determine Appropriate Intervention Time in Rats [PDF]
Basic and Clinical Neuroscience, 2020 Introduction: The proteoglycans of the extracellular matrix increases in the glial scar during spinal cord injury and significantly affects the inhibition of axonal regeneration.
Sara Rezaei +5 more
doaj +2 more sources