Results 161 to 170 of about 232,697 (206)

Dermatan Sulfate as a Potential Therapeutic Agent

open access: yesGeneral Pharmacology, 1995
1. Dermatan sulfate is a linear, sulfated polysaccharide and is a glycosaminoglycan component of several important proteoglycans. This minireview discusses the biosynthesis, structure and biological function of dermatan sulfate proteoglycans. 2.
Robert J. Linhardt, R E Hileman
exaly   +4 more sources

Dermatan 4-O-Sulfotransferase 1 Is Pivotal in the Formation of Iduronic Acid Blocks in Dermatan Sulfate.

open access: yesGlycobiology, 2009
Chondroitin/dermatan sulfate is a highly complex linear polysaccharide ubiquitously found in the extracellular matrix and at the cell surface. Several of its functions, such as binding to growth factors, are mediated by domains composed of alternating ...
Anders Malmström, Marco Maccarana
exaly   +3 more sources

Low Molecular Weight Dermatan Sulfate as an Antithrombotic Agent Structure-Activity Relationship Studies

open access: yesBiochemical Pharmacology, 1994
Biochemical Pharmacology, 47, 1241-1252Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Umesh R Desai, Robert J. Linhardt
exaly   +2 more sources
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Biosynthesis of Chondroitin/Dermatan Sulfate

IUBMB Life, 2002
AbstractChondroitin sulfate and dermatan sulfate are synthesized as galactosaminoglycan polymers containing N ‐acetylgalactosmine alternating with glucuronic acid. The sugar residues are sulfated to varying degrees and positions depending upon the tissue sources and varying conditions of formation.
Jeremiah E Silbert, Geetha Sugumaran
exaly   +3 more sources

Purification, Structural Characterization and Antiproliferative Properties of Chondroitin Sulfate/Dermatan Sulfate From Tunisian Fish Skins [PDF]

open access: yesInternational Journal of Biological Macromolecules, 2017
Chondroitin sulfate/dermatan sulfate GAGs were extracted and purified from the skins of grey triggerfish (GTSG) and smooth hound (SHSG). The disaccharide composition produced by chondroitinase ABC treatment showed the presence of nonsulfated disaccharide,
Ali Bougatef   +2 more
exaly   +2 more sources

Chondroitin/Dermatan Sulfate Purified From Corb (Sciaena umbra) Skin and Bone: In Vivo Assessment of Anticoagulant Activity

open access: yesInternational Journal of Biological Macromolecules, 2020
The present work deals with the extraction and purification of chondroitin sulfate/dermatan sulfate from skin (CSG) and bone (CBG) of corb (Sciaena umbra).
Ali Bougatef, Assaad Sila, Nicola Volpi
exaly   +2 more sources

Enzymatic Reconstruction of Dermatan Sulfate

Biochemical and Biophysical Research Communications, 2000
We investigated the enzymatic reconstruction of dermatan sulfate (DS) using the transglycosylation reaction of testicular hyaluronidase. First, in order to insert the IdoA-GalNAc disaccharide unit into chondroitin sulfate chains consisting of GlcA-GalNAc disaccharide units, desulfated DS as a donor and pyridylaminated (PA) chondroitin 6-sulfate (Ch6S ...
K, Takagaki   +4 more
openaire   +2 more sources

The anticoagulant effect of heparan sulfate and dermatan sulfate

Thrombosis Research, 1976
Abstract The potency of the various glycosaminoglycans (GAGs) as anticoagulants in the activated partial thromboplastin time (APTT) test system has been investigated. Heparin, heparan sulfate (HS) and dermatan sulfate (DS) exhibit anticoagulant effect.
A N, Teien, U, Abildgaard, M, Höök
openaire   +2 more sources

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