Results 171 to 180 of about 11,964 (213)

Low molecular weight dermatan sulfate as an antithrombotic agent Structure-activity relationship studies

open access: yesBiochemical Pharmacology, 1994
Biochemical Pharmacology, 47, 1241-1252Note : if this item contains full text it may be a preprint, author manuscript, or a Gold OA copy that permits redistribution with a license such as CC BY.
Robert J Linhardt   +2 more
exaly   +2 more sources

Purification, structural characterization and antiproliferative properties of chondroitin sulfate/dermatan sulfate from tunisian fish skins [PDF]

open access: yesInternational Journal of Biological Macromolecules, 2017
Chondroitin sulfate/dermatan sulfate GAGs were extracted and purified from the skins of grey triggerfish (GTSG) and smooth hound (SHSG). The disaccharide composition produced by chondroitinase ABC treatment showed the presence of nonsulfated disaccharide,
Fatma Krichen   +2 more
exaly   +2 more sources

Biological functions of iduronic acid in chondroitin/dermatan sulfate

open access: yesFEBS Journal, 2013
The presence of iduronic acid in chondroitin/dermatan sulfate changes the properties of the polysaccharides, as it generates a more flexible chain with increased binding potentials.
Martin A Thelin   +2 more
exaly   +2 more sources
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Biosynthesis of Chondroitin/Dermatan Sulfate

IUBMB Life, 2002
AbstractChondroitin sulfate and dermatan sulfate are synthesized as galactosaminoglycan polymers containing N ‐acetylgalactosmine alternating with glucuronic acid. The sugar residues are sulfated to varying degrees and positions depending upon the tissue sources and varying conditions of formation.
Jeremiah E Silbert, Geetha Sugumaran
exaly   +3 more sources

Enzymatic Reconstruction of Dermatan Sulfate

Biochemical and Biophysical Research Communications, 2000
We investigated the enzymatic reconstruction of dermatan sulfate (DS) using the transglycosylation reaction of testicular hyaluronidase. First, in order to insert the IdoA-GalNAc disaccharide unit into chondroitin sulfate chains consisting of GlcA-GalNAc disaccharide units, desulfated DS as a donor and pyridylaminated (PA) chondroitin 6-sulfate (Ch6S ...
K, Takagaki   +4 more
openaire   +2 more sources

Dermatan sulfate and chondroitin 6-sulfate conformations

Biochemical and Biophysical Research Communications, 1973
Abstract X-ray diffraction patterns show that dermatan sulfate in oriented, crystalline films occurs as two or three or eight-fold helices. The two-fold helix has a greater axial rise per disaccharide residue [ h = 9.6 A ] than the corresponding chondroitin 6-sulfate helix [ h = 9.3 A ] .
S, Arnott   +3 more
openaire   +2 more sources

The anticoagulant effect of heparan sulfate and dermatan sulfate

Thrombosis Research, 1976
Abstract The potency of the various glycosaminoglycans (GAGs) as anticoagulants in the activated partial thromboplastin time (APTT) test system has been investigated. Heparin, heparan sulfate (HS) and dermatan sulfate (DS) exhibit anticoagulant effect.
A N, Teien, U, Abildgaard, M, Höök
openaire   +2 more sources

Synthesis of disaccharide fragments of dermatan sulfate

Carbohydrate Research, 1989
Condensation of crystalline methyl 2-azido-4,6-O-benzylidene-2-deoxy-beta-D-galactopyranoside with methyl (2,3,4-tri-O-acetyl-alpha-L-idopyranosyl bromide)uronate in dichloromethane, in the presence of silver triflate and molecular sieve, provided 54% of methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(methyl 2,3,4-tri-O-acetyl-alpha-L-idopyranosyluronate)
MARRA, Alberto   +3 more
openaire   +3 more sources

Immunology of Chondroitin/Dermatan Sulfate

1995
Variable substitutions and locations of the sulfate esters along the backbone of chondroitin/dermatan sulfate chains, combined with their carbohydrate structures, present topographies to immune systems which can be recognized as antigenic. This has led to the development of a number of monoclonal antibodies which recognize distinct epitopes in the ...
V C, Hascall   +3 more
openaire   +2 more sources

Dermatan sulfates of normal and scarred fascia

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2001
We evaluated the composition of dermatan sulfates (DS) derived from 23 samples of normal and 23 samples of scarred fascia lata. We analyzed the molecular weight of intact DS chains and the length of chain regions comprising: (1) clusters of L-iduronate-containing disaccharides ("iduronic sections"); (2) clusters of D-glucuronate-containing ...
E M, Kozma, K, Olczyk, A, Głowacki
openaire   +2 more sources

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