Results 121 to 130 of about 80,074 (304)

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, EarlyView.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

The role of delta6-desaturase acyl-carrier specificity in the efficient synthesis of long-chain polyunsaturated fatty acids in transgenic plants [PDF]

, 2012
The role of acyl-CoA-dependent Delta 6-desaturation in the heterologous synthesis of omega-3 long-chain polyunsaturated fatty acids was systematically evaluated in transgenic yeast and Arabidopsis thaliana.
Sayanova, O. V., Haslam, R. P., Napier, J. A., Ruiz-Lopez, N.   +3 more
core   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

Corrigendum: Key Enzymes in Fatty Acid Synthesis Pathway for Bioactive Lipids Biosynthesis

Frontiers in Nutrition, 2022
Xiao-Yan Zhuang, Yong-Hui Zhang, An-Feng Xiao, Ai-Hui Zhang, Bai-Shan Fang, Bai-Shan Fang   +5 more
doaj   +1 more source

Modulation in delta 9, delta 6, and delta 5 fatty acid desaturase activity in the human intestinal CaCo-2 cell line.

Journal of Lipid Research, 1995
We report the influence of media lipids, growth in lipid-poor medium, and cell differentiation on delta 9, delta 6, and delta 5 desaturase activity in the human CaCo-2 enterocyte cell line.
V C Dias, H G Parsons
doaj   +1 more source

Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid

, 2007
A number of studies have investigated the effects of fish oil on the production of pro-inflammatory cytokines using peripheral blood mononuclear cell models.
Mullen, Anne C, Loscher, Christine E, Weldon, Sinéad M, Roche, Helen M, Hurley, Lisa A   +4 more
core   +1 more source

SMILE: Extraction‐free submicron‐resolution mapping of lipid chain length and unsaturation by stimulated Raman imaging

VIEW, EarlyView.
In this work, we develop submicron‐resolution mapping of intracellular lipid elements (SMILE) as an extraction‐free vibrational spectroscopic imaging platform based on hyperspectral stimulated Raman scattering microscopy with a spectral analysis pipeline for pixel‐resolved lipid profiling.
Yihui Zhou, Xiangjie Huang, Xingxin Liu, Ling Zhang, Jie Huang, Jing Zhao, Yongqing Zhang, Jin Zhang, Yanqing Gong, Delong Zhang, Hyeon Jeong Lee   +10 more
wiley   +1 more source

Trans-vaccenate is Δ13-desaturated by FADS3 in rodents

Journal of Lipid Research, 2013
Fatty acid desaturases play critical roles in regulating the biosynthesis of unsaturated fatty acids in all biological kingdoms. As opposed to plants, mammals are so far characterized by the absence of desaturases introducing additional double bonds at ...
Vincent Rioux, Frédérique Pédrono, Hélène Blanchard, Cécile Duby, Nathalie Boulier-Monthéan, Laurence Bernard, Erwan Beauchamp, Daniel Catheline, Philippe Legrand   +8 more
doaj   +1 more source

Ozone‐driven degradation of sex pheromone in Plutella xylostella: Implications for reproductive communication and mating success

Insect Science, EarlyView.
In this study, we examined whether realistic ozone concentrations can interfere with sexual communication in the insect pest Plutella xylostella, the diamondback moth. Ozone exposure caused a degradation of pheromone components, leading to significant changes in blend composition and component ratios.
Francesco Sorrentino, Delia M. Pinto‐Zevallos, Oksana Skaldina, James D. Blande   +3 more
wiley   +1 more source

Effects of feeding rapeseed oil, soybean oil or linseed oil on stearoyl-CoA desturase expression in the mammary gland of dairy cows

, 2009
Extensive biohydrogenation of dietary fatty acids (FA) occurs in the rumen of dairy cattle, giving rise to a high proportion of saturated FA in milk fat. Saturated FA may contribute to increased risks of cardiovascular disease and the metabolic syndrome (
Dijkstra, J., van Vuuren, A.M., Vuuren, A.M., van, van Baal, J., Baal, J., van, Hengel, D., van de, Jacobs, A.A.A., van de Hengel, D.   +7 more
core