Results 111 to 120 of about 80,074 (304)

Isolation and functional characterisation of a fads2 in rainbow trout (Oncorhynchus mykiss) with ∆5 desaturase activity [PDF]

, 2016
Rainbow trout, Oncorhynchus mykiss, are intensively cultured globally. Understanding their requirement for long-chain polyunsaturated fatty acids (LC-PUFA) and the biochemistry of the enzymes and biosynthetic pathways required for fatty acid synthesis is
John A Donald, Abdul Hamid, Noor Khalidah, Turchini, Giovanni M, Monroig, Oscar, Tocher, Douglas R, Noor Khalidah Abdul Hamid, Óscar Monroig, Giovanni M Turchini, Donald, John, Greta Carmona-Antoñanzas, Carmona-Antonanzas, Greta, Douglas R Tocher   +11 more
core   +1 more source

ACE‐inhibitory peptide Leu‐Tyr‐Ala in skeletal muscle actin exhibits anti‐aging effects through the inhibition of acn‐1 in Caenorhabditis elegans

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Inhibitors of angiotensin‐converting enzyme (ACE) are used in pharmaceuticals and functional foods. Captopril, a well‐known ACE inhibitor, extends the lifespan of the nematode Caenorhabditis elegans. Bioactive peptides derived from food sources are considered safe ACE inhibitors.
Issei Yokoyama, Minori Yamane, Kanaho Watanabe, Abdul Fatah, Yusuke Komiya, Jun Nagasao, Keizo Arihara   +6 more
wiley   +1 more source

Conversion of hexadecanoic acid to hexadecenoic acid by rat Δ6-desaturase

Journal of Lipid Research, 2003
A higher content of C16:1 n-10 has recently been reported in the preputial gland of mice with a targeted disruption of the gene encoding stearoyl-CoA desaturase 1 (SCD1−/− mice) when compared with wild-type mice.
Hervé Guillou, Vincent Rioux, Daniel Catheline, Jean-Noël Thibault, Monique Bouriel, Sophie Jan, Sabine D'Andrea, Philippe Legrand   +7 more
doaj   +1 more source

Biosynthesis of fucoxanthin and diadinoxanthin and function of initial pathway genes in Phaeodactylum tricornutum

, 2012
The biosynthesis pathway to diadinoxanthin and fucoxanthin was elucidated in Phaeodactylum tricornutum by a combined approach involving metabolite analysis identification of gene function.
Sandmann, Gerhard, Steiger, Sabine, Büchel, Claudia, Breitenbach, Jürgen, Dambek, Michael, Eilers, Ulrike   +5 more
core   +1 more source

Higher Increases in Plasma n‐3 Polyunsaturated Fatty Acids Following Fish Oil Supplementation in Postmenopausal Females Compared With Age‐Matched Males

Lipids, EarlyView.
ABSTRACT The effects of fish oil supplementation on omega‐3 (n‐3) polyunsaturated fatty acids, particularly intermediates between eicosapentaenoic acid (EPA, 20:5n‐3) and docosahexaenoic acid (DHA, 22:6n‐3), that may provide valuable metabolic information, have not been fully characterized in older populations.
David C. R. Ku, Insaf Loukil, Annick Vachon, Mélanie Plourde, Adam H. Metherel   +4 more
wiley   +1 more source

Calculated Desaturase and Elongase Activity Indices.

, 2019
Product/precursor ratio of the percentages of individual FAs represent desaturase and elongase activity indices: (A) C16:1n-7/C16:0 = Δ9-desaturase (D9D16), (B) C18:1n-9/C18:0 = Δ9-desaturase (D9D18), (C) 18:3n-6/C18:2n-6 = Δ6-desaturase (D6D), (D) C20 ...
Stephanie Adolph (4975112), Carola Schedlbauer (6494903), Axel Schöniger (6494909), Dominique Blaue (6494906), Herbert Fuhrmann (345746), Walter Brehm (5792732), Ingrid Vervuert (6494915), Claudia Gittel (6494912)   +7 more
core   +1 more source

LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet‐Induced Ferroptosis, and These Effects are Enhanced by mTOR Inhibition

Molecular Carcinogenesis, EarlyView.
ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang, Ali Nakhi, Peter I. Dosa, Gunda I. Georg, Fekadu Kassie   +4 more
wiley   +1 more source

nuclear phytoene desaturase (PDS) alignment

, 2018
nuclear phytoene desaturase (PDS ...
Nicholas P. Tippery (8140428), Vignu Sivadas (8140437), Nicole L. Sears (8140431), Autumn B. Zentner (8140434)   +3 more
core   +1 more source

Elevation of Stearoyl‐Coenzyme A Desaturase and Monounsaturated Fatty Acids in Parkinson's Disease Serum

Movement Disorders, EarlyView.
Abstract Background Emerging evidence indicates that dysregulation of monounsaturated fatty acids (MUFAs), synthesized by the enzyme stearoyl‐coenzyme A desaturase (SCD), impacts on α‐synuclein pathology in the Parkinson's disease (PD) brain. Objective The objective of this study was to analyze SCD and MUFA‐enriched lipids in the periphery of patients ...
Finula I. Isik, Russell Pickford, Michelle Chua, Simon J.G. Lewis, Nicolas Dzamko, Woojin Scott Kim   +5 more
wiley   +1 more source

The desaturase gene family : an evolutionary study of putative speciation genes in 12 species of Drosophila

, 2012
The formation and persistence of species are the subject of much debate among biologists. Many species of Drosophila are behaviourally isolated, meaning that heterospecific individuals are not attracted to one another and do not interbreed.
Keays, Maria C.
core