Results 201 to 210 of about 80,074 (304)

Progress and Challenges in Faba Bean Genetic Engineering

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Legumes are essential for global food security, serving as a vital source of plant‐based protein and playing a significant role in sustainable agricultural practices. Among legumes, faba bean (Vicia faba L.) is noteworthy due to its high‐protein content, broad climate adaptation, and suitability for cultivation in temperate regions.
Simone A. Gierlich, Thilani B. Jayakody, Sruthy Maria Augustine, Huijun Liu, Marko Jääskeläinen, Triin Vaisalu, Rod. J. Snowdon, Stig U. Andersen   +7 more
wiley   +1 more source

Correction: Efficient CRISPR/Cas9-mediated genome editing of <i>phytoene desaturase</i> in Musa-AAA: a critical step for genetic improvement of East African highland bananas. [PDF]

Front Plant Sci
Kalungi F, Mulindwa J, Muiruri SK, Ntui VO, Mustafa AS, Namanya PB, Kubiriba J, Tripathi L, Barekye A, Tindamanyire JM.   +9 more
europepmc   +1 more source

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

MedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang, Ling Wang   +12 more
wiley   +1 more source

Molecular basis of fatty acid composition diversity in different avocado cultivars. [PDF]

BMC Genomics
Chen M, Chen Z, Lin F, Cai Y, Huang T, Zheng Y, Yin X, Yang Y, Kong X, Yang Y.   +9 more
europepmc   +1 more source

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

MedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou, Sheng He, Lili He, Kun Liu, Wen Tang, Deming Wang, Jing Gui, Zhiying Zeng, Yan Wang, Wenjie Liu, Ren Jing   +10 more
wiley   +1 more source

Mendelian Randomization Identifies Lipidomic Signatures of Depression Risk That Are Partly Reflected in Cortisol-Induced Membrane Remodeling and Modulated by St. John's Wort Extract (Ze 117). [PDF]

Int J Mol Sci
Freytag V, Butterweck V, de Quervain DJ, Boonen G, Papassotiropoulos A.   +4 more
europepmc   +1 more source

Stearoyl‐CoA Desaturase‐1 Drives Tumor Growth by Interacting With Histone Deacetylase‐2 and Deacetylating Nucleophosmin‐1

MedComm, Volume 7, Issue 6, June 2026.
Hypoxia induces SCD1 and PLIN2 to drive lipid droplet‐dependent metabolic adaptation in cancer cells. PLIN2 supports survival under stress, whereas SCD1 promotes proliferation upon reoxygenation and remodels the acetylome via HDAC2‐mediated NPM1 deacetylation and destabilization.
Coline Wery, Laetitia Montero‐Ruiz, Eric Bonneil, Mohammad Farran, Robin Jehay, Quentin Herrara Garfia, Gregory Fettweis, Silvia Blacher, Charles Pottier, Gael Cobraiville, Yasmine Boumahd, Olivier Peulen, Agnès Noël, Franck Dequiedt, Marianne Fillet, Nor Eddine Sounni   +15 more
wiley   +1 more source

Does Gum Arabic Alter Gene Expression? Diabetic and Obesity as Models: A Mini Review

Modern Agriculture, Volume 4, Issue 1, June 2026.
Gum Arabic (GA) modulates obesity‐ and diabetes‐related gene expression, reducing pro‐inflammatory cytokines (IL‐6, TNF‐α, IL‐1β) and increasing IL‐10. GA elevates pAMPK, pACC, and GLP‐1 while decreasing FASN and leptin, indicating improved energy and lipid metabolism. Oxidative stress markers (SOD, GPx, CAT) rise with GA, alongside increased GLUT3 and
Saber Y. Adam, Taha Hussein Musa, Hassan Hussein Musa, Ahmed A. Saleh, Abdelkareem A. Ahmed   +4 more
wiley   +1 more source

Intracranial calcifications in DEGS1-Related Leukodystrophy: a potentially under-recognised neuroimaging feature. [PDF]

Neurol Sci
Vaia Y, Kim N, Jeyasingh S, Sudhakar S, Mankad K, Biswas A, Siddiqui A, Mundy H, Hedderly T, Singh RR.   +9 more
europepmc   +1 more source

Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi, Xi Liu, Xi Zhang, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source