Results 61 to 70 of about 3,518 (193)
In the present study, digestion pattern of purified bovine κ-casein (κ-CN) variants A, B, E as well as desialylated variant B, using INFOGEST 2.0 in vitro gastrointestinal digestion were investigated using peptidomics.
Bulei Sheng +5 more
doaj +1 more source
Apoptotic modification of glycosphingolipids of human granulocytes
The phenomenon of programmed apoptotic desialylation of cell glycans was described previously. However, the possibility of this process application to the sialylated glycolipids of membranes stayes unknown.
A. M. Tomin +5 more
doaj +1 more source
Masses and structures of the N-glycans after desialylation with acetic acid.
Masses and structures of the N-glycans after desialylation with acetic acid.
Stephen F. Madden (452403) +10 more
core +1 more source
MHC Class I Stability is Modulated by Cell Surface Sialylation in Human Dendritic Cells
Maturation of human Dendritic Cells (DCs) is characterized by increased expression of antigen presentation molecules, and overall decreased levels of sialic acid at cell surface. Here, we aimed to identify sialylated proteins at DC surface and comprehend
Zélia Silva +10 more
doaj +1 more source
A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang +8 more
wiley +1 more source
Measurement of Circulating Desialylated Glycoproteins and Correlation with Hepatocellular Damage [PDF]
Addition of increasing amounts of (125)I-labeled desialylated thyroxine-binding globulin (DTBG) to hepatic cell membranes resulted in a progressive increase in binding. Saturability of membrane sites was indicated by a concentration beyond which further increases in [(125)I]DTBG resulted in no further binding.
J S, Marshall +5 more
openaire +2 more sources
The Binding of Desialylated Glycoproteins by Plasma Membranes of Rat Liver
Abstract Evidence is presented to identify plasma membranes of liver as the major locus of binding for circulating glycoproteins. The binding process involves a dual role for sialic acid in that its presence on the membranes is essential, whereas its presence on the glycoprotein is incompatible with binding.
W E, Pricer, G, Ashwell
openaire +2 more sources
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song +3 more
wiley +1 more source
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir +4 more
wiley +1 more source

