Results 51 to 60 of about 3,518 (193)

Serum Testosterone Response to Desialylated Human Choriogonadotropin in Man [PDF]

Journal of Andrology, 1988
To assess the in vivo steroidogenic activity of desialylated human choriogonadotropin (hCG) in man, highly purified desialylated hCG was administered as a constant intravenous infusion over 6 hours to four normal men at a rate sufficient to maintain substantial levels of desialylated hCG in the serum.
L, Liu, R E, Wehmann, C, Rosa, S, Birken, B C, Nisula   +4 more
openaire   +2 more sources

Targeted Desialylation Overcomes Glyco-Immune Checkpoints and Potentiates the Anticancer Immune Response in Vivo [PDF]

, 2019
Currently approved immune checkpoint inhibitor (ICI) therapies targeting the PD-1 and CTLA-4 receptor pathways are powerful treatment options for certain cancers; however, the majority of patients across cancer types still fail to respond.
Elliot C., Woods, Green, Ahn, Han, Xiao, Julia T., Tanzo, Stacy A., Malaker, Caitlyn L., Miller, Michal A., Stanczak, Carolyn, Bertozzi, Melissa, Gray, Heinz, Läubli, Natália R., Mantuano, Johan F. A., Pijnenborg, Payton A., Weidenbacher   +12 more
core   +2 more sources

Table_1_Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia.docx

, 2022
Thrombocytopenia is a multifactorial condition that frequently involves concomitant defects in platelet production and clearance. The physiopathology of low platelet count in thrombocytopenia remains unclear. Sialylation on platelet membrane glycoprotein
Qiaoyun Zheng (12332060), Jianda Hu (545445), Liping Luo (1885879), Shimuye Kalayu Yirga (10888536), Yuwen Chen (7055768), Yongzhi Zheng (11425156), Donghui Gan (10888533), Yingyu Chen (161120), Na Zhang (333280), Lin Fu (320968), Zhenxing Lin (12332063), Qizhen Shi (2644975)   +11 more
core   +1 more source

Sialic acid as the potential link between lipid metabolism and inflammation in the pathogenesis of atherosclerosis [PDF]

Brazilian Journal of Medical and Biological Research, 2023
In the modern world, cardiovascular diseases have a special place among the most common causes of death. Naturally, this widespread problem cannot escape the attention of scientists and researchers. One of the main conditions preceding the development of
A.V. Poznyak, D.A. Kashirskikh, A.Y. Postnov, M.A. Popov, V.N. Sukhorukov, A.N. Orekhov   +5 more
doaj   +1 more source

Detection of desialylated forms of human chorionic gonadotropin

Clinica Chimica Acta, 1987
Urinary forms of human chorionic gonadotropin (hCG) with oligosaccharides deficient in sialic acid content (ashCG) have been reported to be excreted by patients with choriocarcinoma in greater amounts than by healthy, pregnant women. Although ashCG potentially could be a useful marker for the diagnosis and management of gestational trophoblastic ...
S, Imamura, E G, Armstrong, S, Birken, L A, Cole, R E, Canfield   +4 more
openaire   +2 more sources

Image_1_Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia.tif

, 2022
Thrombocytopenia is a multifactorial condition that frequently involves concomitant defects in platelet production and clearance. The physiopathology of low platelet count in thrombocytopenia remains unclear. Sialylation on platelet membrane glycoprotein
Qiaoyun Zheng (12332060), Jianda Hu (545445), Liping Luo (1885879), Shimuye Kalayu Yirga (10888536), Yuwen Chen (7055768), Yongzhi Zheng (11425156), Donghui Gan (10888533), Yingyu Chen (161120), Na Zhang (333280), Lin Fu (320968), Zhenxing Lin (12332063), Qizhen Shi (2644975)   +11 more
core   +1 more source

Table_3_Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia.docx

, 2022
Thrombocytopenia is a multifactorial condition that frequently involves concomitant defects in platelet production and clearance. The physiopathology of low platelet count in thrombocytopenia remains unclear. Sialylation on platelet membrane glycoprotein
Qiaoyun Zheng (12332060), Jianda Hu (545445), Liping Luo (1885879), Shimuye Kalayu Yirga (10888536), Yuwen Chen (7055768), Yongzhi Zheng (11425156), Donghui Gan (10888533), Yingyu Chen (161120), Na Zhang (333280), Lin Fu (320968), Zhenxing Lin (12332063), Qizhen Shi (2644975)   +11 more
core   +1 more source

Table_2_Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia.docx

, 2022
Thrombocytopenia is a multifactorial condition that frequently involves concomitant defects in platelet production and clearance. The physiopathology of low platelet count in thrombocytopenia remains unclear. Sialylation on platelet membrane glycoprotein
Qiaoyun Zheng (12332060), Jianda Hu (545445), Liping Luo (1885879), Shimuye Kalayu Yirga (10888536), Yuwen Chen (7055768), Yongzhi Zheng (11425156), Donghui Gan (10888533), Yingyu Chen (161120), Na Zhang (333280), Lin Fu (320968), Zhenxing Lin (12332063), Qizhen Shi (2644975)   +11 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

From haemostasis to immunity: The expanding frontiers of platelet biology

British Journal of Haematology, EarlyView.
Platelets are versatile cells whose functions extend far beyond haemostasis and thrombosis, actively regulating innate and adaptive immunity, angiogenesis, lymphangiogenesis, liver regeneration, atherosclerosis and tumour metastasis. This demonstrates their central role in various physiological processes and multiple life‐threatening diseases ...
Xun Grace Wu, Nicole Tomei, Heyu Ni
wiley   +1 more source