Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion. [PDF]
PLoS ONE, 2013 Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1-4 and desmocollin (Dsc) 1-3 build the adhesive core of ...
Hartlieb, Eva +5 more
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Evaluation of autoantibodies to desmoglein-2 in dogs with and without cardiac disease [PDF]
Scientific Reports, 2023 Autoantibodies to desmoglein-2 have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC) in people. ARVC is a common disease in the Boxer dog.
Ashley L. Walker +6 more
doaj +2 more sources
International Journal of Trichology, 2013 Desmogleins (Dsgs) are calcium-dependent, transmembrane glycoproteins belonging to the desmosomal cadherin superfamily, which play significant roles in selective calcium ions (Ca(2+)) dependent adhesion interactions between cell surfaces. Four subtypes of Dsg have been identified.
PramodKumar Nigam
openalex +5 more sources
Detection of Desmoglein-3 Auto-Antibodies in Patients with Lichen Planus [PDF]
Egyptian Journal of Medical Research, 2022 There is controversy about the role of auto anti-bodies against desmoglein 3 (Dsg 3) in the pathogenesis of lichen planus (LP). The goal of this study is to detect desmoglein-3 auto-antibodies in lichen planus patients comparted to normal control persons
Abd-El Aziz El-Rifaie +3 more
doaj +2 more sources
Rituximab in Pemphigus Foliaceous With Autoantibodies Against Both Desmoglein 1 and Desmoglein 3 [PDF]
European Journal of Dermatology, 2011 ejd.2011.1288 Auteur(s) : Rodrigo CARVALHO1 rodrigoaraujocarvalho@gmail.com, Paula MAIO1, Daniela CUNHA1, Isabel FREITAS1, Ana AFONSO2, Jorge CARDOSO1 1 Department of Dermatology and Venereology, Curry Cabral Hospital, Lisbon, Portugal 2 Department of Pathology, Curry Cabral Hospital, Lisbon, Portugal Reprints.: R. CARVALHO Pemphigus foliaceous (PF) is
Afonso, A +5 more
core +2 more sources
Factors associated with persistent anti-desmoglein positivity after remission in pemphigus vulgaris: a prospective registry-based cohort study [PDF]
Frontiers in ImmunologyIntroductionAnti-desmoglein (Dsg) antibodies are well-established markers correlated with clinical phenotype and disease severity in pemphigus vulgaris (PV).
Yuxi Zhou +7 more
doaj +2 more sources
Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus
Frontiers in Immunology, 2018 Keratins are crucial for the anchorage of desmosomes. Severe alterations of keratin organization and detachment of filaments from the desmosomal plaque occur in the autoimmune dermatoses pemphigus vulgaris and pemphigus foliaceus (PF), which are mainly ...
Franziska Vielmuth +7 more
doaj +2 more sources
Desmoglein-3 autoantibodies in tissues of oral lichen planus patients and its correlation with disease severity: case-control study [PDF]
BMC Oral HealthBackground Due to the not fully understood exact pathogenesis of oral lichen planus, the patients receive symptomatic management, rather than a curative treatment.
Doaa Abdelwadood +3 more
doaj +2 more sources
Desmoglein autoantibodies and disease severity in pemphigus patients – correlations and discrepancies [PDF]
Folia Medica, 2023 Aim: To assess the correlation between the levels of anti-desmoglein-1 and anti-desmoglein-3 autoantibodies and disease severity in pemphigus patients.
Zhaneta H. Zhelyazkova +4 more
doaj +3 more sources
The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells [PDF]
Scientific Reports, 2016 Fatemeh Askarian +2 more
exaly +5 more sources