Results 11 to 20 of about 15,537 (248)
Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury [PDF]
Mucosal Immunology, 2018 Michael Meir +2 more
exaly +2 more sources
Frontiers in Immunology, 2023 Pemphigus vulgaris (PV) is an acquired autoimmune blistering disease characterized by the production of autoantibodies targeting desmosomal cadherins, primarily desmoglein 1 and desmoglein 3, leading to acantholysis. The etiology of PV is multifactorial,
Ines Lakoš Jukić +4 more
doaj +1 more source
Desmoglein 2 depletion leads to increased migration and upregulation of the chemoattractant secretoneurin in melanoma cells. [PDF]
PLoS ONE, 2014 During development and progression of malignant melanoma, an important role has been attributed to alterations of cell-cell adhesions, in particular, to a "cadherin switch" from E- to N-cadherin.
Wiebke K Peitsch +7 more
doaj +1 more source
Frontiers in Immunology, 2021 Desmogleins are involved in cell adhesion conferring structural skin integrity. However, their role in inflammation has been barely studied, and whether desmoglein-4 modulates psoriasis lesions is completely unknown. In this study, we assessed the impact
Tamara Moreno-Sosa +14 more
doaj +1 more source
Efficacy of Rituximab in Patients with Autoimmune Bullous Disease: A Retrospective Cohort Study
Van Tıp Dergisi, 2021 INTRODUCTION: The aim of this study was to evaluate the effectiveness of rituximab in autoimmune bullous diseases. METHODS: In this study, the data of patients who received rituximab treatment for autoimmune bullous disease in our clinic between 2012 and
Özge Aşkın +3 more
doaj +1 more source
Detection of anti-desmoglein antibodies in oral lichen planus: What do we know so far
Frontiers in Immunology, 2022 Oral lichen planus (OLP) is an inflammatory disease of the oral mucosa. Clinically, two main subsets are described, namely non-erosive and erosive OLP. While non-erosive OLP is usually responsive to local therapies, erosive OLP is often refractory also ...
Dario Didona, Michael Hertl
doaj +1 more source
Frontiers in Immunology, 2022 Paraneoplastic pemphigus (PNP) is an autoimmune bullous disease associated with underlying neoplasms and characterized by antibodies against desmoglein 3 (Dsg 3) and plakins.
Xue Wang +28 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 While classic cadherin-actin connections in adherens junctions (AJs) have ancient origins, intermediate filament (IF) linkages with desmosomal cadherins arose in vertebrate organisms.
Kathleen J. Green +13 more
doaj +1 more source
Biology, 2023 Background: Pemphigus is a life-threatening blistering autoimmune disease. Several forms, characterized by the presence of autoantibodies against different autoantigens, have been described.
Roberta Lotti +5 more
doaj +1 more source