Results 31 to 40 of about 7,325 (186)
Frontiers in Immunology, 2019 Pemphigus is an autoimmune dermatosis in which mucocutaneous blisters are induced primarily by autoantibodies against Desmoglein (Dsg) 1 and 3. Pemphigus vulgaris (PV) usually is associated with autoantibodies against Dsg3 whereas pemphigus foliaceus (PF)
Elias Walter +6 more
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Evaluation of autoantibodies to desmoglein-2 in dogs with and without cardiac disease
Scientific Reports, 2023 Autoantibodies to desmoglein-2 have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC) in people. ARVC is a common disease in the Boxer dog.
Ashley L. Walker +6 more
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Cells, 2023 Pemphigus vulgaris (PV) is a potentially lethal autoimmune bullous skin disorder caused by IgG autoantibodies against desmoglein 3 (Dsg3) and Dsg1. During the last three decades, high-dose intravenous immunoglobulins (IVIgs) have been applied as an ...
Christoph Hudemann +4 more
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Archives of Dermatology, 1999 Pemphigus vulgaris (PV) is an autoimmune-blistering disease of the skin and mucous membranes caused by autoantibodies against desmoglein 3 (Dsg3), an epidermal desmosomal adhesion protein of the cadherin family. Cloning of the Dsg3 gene and expression of the protein in a native conformation enabled the recent development of a specific and sensitive ...
P, Lenz +4 more
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Frontiers in Immunology, 2022 Pemphigus is a rare autoimmune disease characterized by the production of pathogenic autoantibodies against desmosomal adhesion proteins, desmoglein 1 and 3.
Joško Miše +4 more
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Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on DSG2 (desmoglein 2), with data on DNA, on the protein encoded, and where the gene is implicated.
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Evaluation of Desmoglein 1 and Desmoglein 3 Autoantibodies in Oral Cancer: A Pilot Study
Journal of Indian Academy of Oral Medicine and Radiology, 2023 Background: Carcinogenesis is a complex multistep process involving alterations at the cellular level. Alteration in cell-to-cell adhesion of oral epithelium plays an important role in carcinogenesis and metastasis. The alterations in the role of desmosomal components due to autoantibodies to desmoglein 1 (DSG 1) and desmoglein
Pavan Kumar Yellarthi +4 more
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Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab
JEADV Clinical Practice, EarlyView.ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle +7 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2001 The LISP-I human colorectal adenocarcinoma cell line was isolated from a hepatic metastasis at the Ludwig Institute, São Paulo, SP, Brazil. The objective of the present study was to isolate morphologically different subpopulations within the LISP-I cell ...
A.C.C. Solimene +3 more
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Desmoglein directs differentiation [PDF]
Journal of Cell Biology, 2009 The cell adhesion protein desmoglein 1 (Dsg1) has an extra function in suppressing EGF receptor (EGFR) signaling, helping skin cells differentiate into the different layers of the epidermis, report [Getsios, Simpson, et al.][1] ![Figure][2] Activated EGFR (green) is only found in the ...
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