Endocytosis of IgG, Desmoglein 1, and Plakoglobin in Pemphigus Foliaceus Patient Skin [PDF]
Frontiers in Immunology, 2019 Pemphigus foliaceus (PF) is one of the two main forms of pemphigus and is characterized by circulating IgG to the desmosomal cadherin desmoglein 1 (DSG1) and by subcorneal blistering of the skin.
Dyah A. M. Oktarina +5 more
doaj +3 more sources
Indian Journal of Dermatology, 2016 Pemphigus vulgaris (PV) is an autoimmune blistering disease elicited by anti-desmoglein (DsG) 3 antibody. Although skin lesions tend to be distributed over the entire body, in some patients, they are confined to a restricted area.
Asuka Yoshifuku +7 more
doaj +4 more sources
IgA pemphigus showing IgA antibodies to desmoglein 1 and 3 [PDF]
Dermatology Practical & Conceptual, 2016 Background: IgA pemphigus is a rare autoimmune vesiculo-pustular skin disease. Only approximately 70 cases have been reported to date. We report a case of IgA pemphigus with IgA antibodies to desmoglein 1 (Dsg1) and desmoglein 3 (Dsg3).
Salama Hegazy +5 more
doaj +5 more sources
Detection of Autoantibodies against Recombinant Desmoglein 1 and 3 Molecules in Patients with Pemphigus vulgaris: Correlation with Disease Extent at the Time of Diagnosis and during Follow-Up [PDF]
Clinical and Developmental Immunology, 2009 The recent availability of cDNA clones for pemphigus antigens has allowed the production of recombinant desmoglein 1 and desmoglein 3 molecules and the development of an ELISA approach in order to determine levels of antibodies to them.
Anna Belloni-Fortina +6 more
doaj +2 more sources
The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells [PDF]
Scientific Reports, 2016 Fatemeh Askarian +2 more
exaly +7 more sources
Ultrastructural skin alterations of healthy subjects with anti-desmoglein 1 antibodies in endemic areas to pemphigus foliaceus: A case series [PDF]
Journal of Translational Autoimmunity, 2023 Background: Endemic pemphigus foliaceus and endemic pemphigus vulgaris are autoimmune dermatologic disorders endemic to the Peruvian Amazon. Objective: To determine the ultrastructural skin alterations of three healthy subjects with anti DSG-1 antibodies
Willy Ramos +10 more
doaj +2 more sources
Pemphigus Foliaceus Autoantibodies Induce Redistribution Primarily of Extradesmosomal Desmoglein 1 in the Cell Membrane [PDF]
Frontiers in Immunology, 2022 The autoimmune dermatosis pemphigus foliaceus (PF) is predominantly caused by IgG autoantibodies against the desmosomal cadherin desmoglein (Dsg) 1. The exact mechanisms that lead to the characteristic epidermal blistering are not yet fully understood ...
Matthias Hiermaier +8 more
doaj +2 more sources
Hereditary epidermolytic palmoplantar keratosis due to a novel desmoglein‐1 mutation: A case report [PDF]
Clinical Case ReportsKey Clinical Message Keratosis palmoplantaris striata type I (SPPK‐I) is a rare autosomal‐dominant type of hereditary epidermolytic palmoplantar keratoderma, which can be caused by mutations in desmoglein‐1 (DSG‐1).
Kevin Koschitzki +8 more
doaj +2 more sources
Mutations in desmoglein 1 cause diverse inherited palmoplantar keratoderma phenotypes: implications for genetic screening. [PDF]
Br J Dermatol, 2017 INTRODUCTION: The inherited palmoplantar keratodermas (PPKs) are a heterogeneous group of genodermatoses, characterised by thickening of the epidermis of the palms and soles. No classification system unites satisfactorily clinical presentation, pathology
Lovgren ML +9 more
europepmc +4 more sources
Differential Pathomechanisms of Desmoglein 1 Transmembrane Domain Mutations in Skin Disease. [PDF]
J Invest Dermatol, 2022 Zimmer SE +6 more
europepmc +3 more sources