Results 91 to 100 of about 23,741,217 (251)
Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior
Advanced Healthcare Materials, EarlyView.Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley +1 more source
Significance of epitope spreading in the pathogenesis of pemphigus vulgaris and foliaceus [PDF]
, 2008 Os pênfigos são dermatoses bolhosas auto-imunes, em que há a produção de auto-anticorpos direcionados contra moléculas de adesão dos epitélios, levando à perda da coesão celular.
AOKI, Valéria +5 more
core +2 more sources
Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum
Dermatologica Sinica, 2015 Desmosomes and corneodesmosomes are the most important adhering junctions, providing strength for the epidermal sheet structure made of living keratinocytes and enucleated stratum corneum corneocytes, respectively.
Yasuo Kitajima
doaj +1 more source
Fogo selvagem: endemic pemphigus foliaceus [PDF]
Anais Brasileiros de Dermatologia, 2018 : Fogo selvagem or endemic pemphigus foliaceus is an autoimmune acantholytic anti-cadherin bullous disease that primarily affects seborrheic areas, which might disseminate.
Günter Hans-Filho +3 more
doaj +1 more source
Dermatologic Therapy, 2018 Dear Editor, Pemphigus vulgaris (PV) is a rare, but potentially fatal autoimmune disease, which could affect both skin and mucous membranes. During this disease, autoantibodies are mainly directed against the adhesion molecules desmoglein (Dsg)1 and Dsg3,
K. Balighi +5 more
semanticscholar +1 more source
Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model
Frontiers in Medicine, 2022 Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine +14 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran +9 more
wiley +1 more source
Lesions of pemphigus vulgaris on irradiated skin [PDF]
, 2009 Summary Pemphigus vulgaris (PV) is an autoimmune blistering disease produced by IgG autoantibodies against desmoglein (Dsg)3. Lesions on the skin and mucosa can, in rare cases, be induced by radiotherapy.
Aguado, L. (Leyre) +4 more
core +1 more source
International Journal of Cosmetic Science, EarlyView.Ageing causes actin cytoskeleton disorganization, a reduction in cellular components associated with the actin cytoskeleton and focal adhesions, and a reduction in skin firmness. Galactomyces ferment filtrate boosts actin stability, increases expression of anchoring junction proteins, including focal adhesions and protects against loss of firmness ...
Steph Crabtree +12 more
wiley +1 more source
Multigene Next-Generation Sequencing Panel Identifies Pathogenic Variants in Patients with Unknown Subtype of Epidermolysis Bullosa: Subclassification with Prognostic Implications [PDF]
, 2017 Purpose: Epidermolysis bullosa (EB), the prototype of heritable blistering diseases, is caused by mutations in as many as 19 distinct genes. In this study, we evaluated the molecular basis of EB in 93 families, many of them of unknown subtype. Methods:
Abiri, Maryam +15 more
core +1 more source