Results 21 to 30 of about 12,405 (225)

Hereditary epidermolytic palmoplantar keratosis due to a novel desmoglein‐1 mutation: A case report [PDF]

Clinical Case Reports
Key Clinical Message Keratosis palmoplantaris striata type I (SPPK‐I) is a rare autosomal‐dominant type of hereditary epidermolytic palmoplantar keratoderma, which can be caused by mutations in desmoglein‐1 (DSG‐1).
Kevin Koschitzki, Bernadett Kurz, Julia Schreml, Judith Fischer, Alrun Hotz, Christoph M. Hammers, Mark Berneburg, Dennis Niebel, Stephan Schreml   +8 more
doaj   +2 more sources

Staphylococcal Exfoliative Toxin B Specifically Cleaves Desmoglein 1 [PDF]

Journal of Investigative Dermatology, 2002
Staphylococcal scalded skin syndrome and its localized form, bullous impetigo, show superficial epidermal blister formation caused by exfoliative toxin A or B produced by Staphylococcus aureus. Recently we have demonstrated that exfoliative toxin A specifically cleaves desmoglein 1, a desmosomal adhesion molecule, that when inactivated results in ...
Yasushi Hanakawa, Takayuki Yamaguchi, John R. Stanley, Koji Nishifuji, Masayuki Amagai, Motoyuki Sugai   +5 more
openaire   +4 more sources

Epidermal stratification requires retromer-mediated desmoglein-1 recycling. [PDF]

Dev Cell, 2022
Hegazy M, Koetsier JL, Huffine AL, Broussard JA, Godsel BM, Cohen-Barak E, Sprecher E, Wolfgeher DJ, Kron SJ, Godsel LM, Green KJ.   +10 more
europepmc   +2 more sources

Alpha-1 antitrypsin promotes re-epithelialization by regulating inflammation and migration [PDF]

Frontiers in Immunology
PurposeRegulation of inflammation and re-epithelialization are critical for efficient wound healing. This study explores the role of human α1-antitrypsin (hAAT), an immunomodulatory protein, in modulating inflammation and promoting re-epithelialization ...
Idan Farber, Idan Farber, Muhammad Wated, Ronen Schuster, Lihie Sheffer, Yuval Anav, Navit Ogen-Shtern, Navit Ogen-Shtern, Alexandra Tsitrina, Diya Tacruri, Anna Bunin, Noah Benjamin Nagar, Maayan Hagbi Bal, Tomer Eliyahu, Dor Halpern, Dor Halpern, Boris Knyazer, Samuel Cohen, Sabri El-Saied, Eli C. Lewis, Eldad Silberstein, Erez Tsumi   +21 more
doaj   +2 more sources

Desmoglein autoantibodies and disease severity in pemphigus patients – correlations and discrepancies [PDF]

Folia Medica, 2023
Aim: To assess the correlation between the levels of anti-desmoglein-1 and anti-desmoglein-3 autoantibodies and disease severity in pemphigus patients.
Zhaneta H. Zhelyazkova, Tsvetana I. Abadjieva, Petya A. Gardjeva, Mariana A. Murdjeva, Tsonka M. Miteva-Katrandzhieva   +4 more
doaj   +3 more sources

The Role of Desmoglein 1 in Gap Junction Turnover Revealed through the Study of SAM Syndrome. [PDF]

J Invest Dermatol, 2020
Cohen-Barak E, Godsel LM, Koetsier JL, Hegazy M, Kushnir-Grinbaum D, Hammad H, Danial-Farran N, Harmon R, Khayat M, Bochner R, Peled A, Rozenblat M, Krausz J, Sarig O, Johnson JL, Ziv M, Shalev SA, Sprecher E, Green KJ.   +18 more
europepmc   +2 more sources

Mutations in desmoglein-1 cause diverse inherited palmoplantar keratoderma phenotypes:implications for genetic screening [PDF]

Br J Dermatol, 2017
Almutawa, Armstrong, Dua-Awereh, Harmon, Has, Hershkovitz, Hunt, Irvine, Itin, Keren, Klijuic, McAleer, Milingou, Nomura, Samuelov, Wan, Whittock   +16 more
core   +3 more sources

The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells [PDF]

Sci Rep, 2016
Ajayi, Clement, Askarian, Fatemeh, Diep, Dzung Bao, Hanssen, Anne-Merethe, Johannessen, Mona, Pettersen, ingvild, Sollid, Johanna U Ericson, Van Sorge, Nina M.   +7 more
core   +4 more sources

Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress. [PDF]

Int J Mol Sci
Tang C, Wang L, Chen Z, Shi X, Chen Y, Yang J, Gao H, Guan C, He S, Zhang L, Zheng S, Yang F, Chen SA, Ma L, Zhang Z, Zhao Y, Liu Q, Wang J, Luo X.   +18 more
europepmc   +2 more sources

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source