Results 71 to 80 of about 13,090 (254)

Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

Frontiers in Medicine, 2022
Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine, Valéria Bumiller-Bini Hoch, Valéria Bumiller-Bini Hoch, Angelica B. Winter Boldt, Detlef Zillikens, Detlef Zillikens, Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Christoph M. Hammers, Christoph M. Hammers, Christoph M. Hammers, Matthias Klinger, Jennifer E. Hundt, Jennifer E. Hundt   +14 more
doaj   +1 more source

Non-classical forms of pemphigus: pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus [PDF]

, 2014
The pemphigus group comprises the autoimmune intraepidermal blistering diseases classically divided into two major types: pemphigus vulgaris and pemphigus foliaceous.
Adriana Maria Porro, Amagai M, Amagai M, Amagai M, Amagai M, Amagai M, Anhalt GJ, Anhalt GJ, Arranz D, Asahina A, Barrance VP, Beutner EH, Borradori L, Bruckner AL, Bull RH, Buxton RS, Camisa C, Chan LS, Chan LS, Chorzelski TP, Chorzelski TP, Cozzani E, Cunha PR, Czernik A, DeMento FJ, Duarte IB, Durham A, Düker I, Emmerson RW, Fang Y, Feng SY, Fernandes IC, Floden CH, Fullerton SH, Gengoux P, Gooptu C, Gruss C, Hashimoto T, Hashimoto T, Hashimoto T, Hashimoto T, Hashimoto T, Hashimoto T, Hashimoto T, Heng A, Hertl M, Hodak E, Horn TD, Hosoda S, Howell SM, Huff JC, Huhn KM, Iida K, Ingber A, Inui S, Ishii K, Ishii N, Jablonska S, Kaplan I, Kimyai-Asadi A, Kitajima Y, Kopp T, Kowalewski C, Kozlowska A, Kubo A, Kubota Y, Laura de Sena Nogueira Maehara, Lebeau S, Leger S, Leithauser LA, Liu Q, Livia de Vasconcelos Nasser Caetano, Lu Y, Lutz ME, Maciejowska E, Maldonado F, Marinovic B, Martel P, Maruyama H, Marzano AV, Mentink LF, Micali G, Miida H, Milvia Maria dos Santos Enokihara, Mimouni D, Mimouni D, Miura T, Miyagawa S, Miyagawa S, Morita E, Morizane S, Moutran R, Müller R, Nakajima K, Nakashima H, Nguyen VT, Nishikawa T, Nousari HC, Nousari HC, O'Toole EA, Ohata C, Ohyama B, Oiso N, Palleschi GM, Patrício P, Prado R, Qian SX, Robinson ND, Ruiz-Genao DP, Sanchez-Palacios C, Santi CG, Santiago-et-Sánchez-Mateos D, Schepens I, Seah PP, Sklavounou A, Sneddon I, Sneddon IB, Szturz P, Tagami H, Taintor AR, Tajima M, Tateishi C, Tsuruta D, Verdier-Sevrain S, Wakahara M, Wallach D, Wallach D, Wang J, Wang J, Weston WL, Yasuda H, Zaraa I, Zaraa I, Zhu X, Zimmermann J   +134 more
core   +4 more sources

Fogo selvagem: endemic pemphigus foliaceus [PDF]

Anais Brasileiros de Dermatologia, 2018
: Fogo selvagem or endemic pemphigus foliaceus is an autoimmune acantholytic anti-cadherin bullous disease that primarily affects seborrheic areas, which might disseminate.
Günter Hans-Filho, Valéria Aoki, Nelise Ritter Hans Bittner, Guilherme Canho Bittner   +3 more
doaj   +1 more source

Pemfigus Vulgaris: Laporan Kasus (Pemphigus vulgaris after covid-19 vaccine: association or coincidence?)

JKS (Jurnal Kedokteran Syiah Kuala), 2022
karena produksi autoantibodi terhadap protein desmosomal kulit, yaitu desmoglein (Dsg) 1 dan desmoglein 1 Dsg3. Beberapa faktor termasuk kerentanan genetik, obat-obatan tertentu dan keganasan telah dilaporkan memicu atau memperburuk PV.
Nanda Earlia, Mimi Maulida, Vella Vella, Mikyal Bulqiah, Aqil Yuniawan Tasrif, Aulia Aulia   +5 more
doaj   +1 more source

A Genome‐Wide Association Study Reveals Desmoglein‐2 Predominance in Japanese Arrhythmogenic Cardiomyopathy [PDF]

J Arrhythm
A GWAS of Japanese arrhythmogenic cardiomyopathy identified a strong signal near DSG2, exceeding the genome‐wide significance of p = 5 × 10–8 (red line). This signal disappeared after excluding carriers of rare DSG2 variants. Stratified analyses indicate that the association reflects a DSG2‐D494A‐mediated synthetic effect driven predominantly by this ...
Ishikawa T, Sonehara K, Sonoda K, Hayashi K, Kato K, Nagase S, Kusano K, Aiba T, Horie M, Ohno S, Okada Y, Makita N.   +11 more
europepmc   +2 more sources

Paraneoplastic pemphigus: insight into the autoimmune pathogenesis, clinical features and therapy [PDF]

, 2017
Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients.
Andrea Ciofalo, Biagio Didona, Bialy-Golan, Dario Didona, Elisa Moliterni, Giannicola Iannella, Giovanni Paolino, Giuseppe Magliulo, Guido Granata, Hainsworth, Martínez De Pablo, Matz, Michele Donati, Mutasim, Nguyen, Patricia Ranuzzi, Santo Mercuri, Schepens, Stefano Calvieri, Su, Vincenzo Falasca, Zimmermann   +21 more
core   +2 more sources

Dupilumab Treatment in Pemphigus: A Report of Three Cases and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Pemphigus vulgaris (PV) and foliaceus (PF) are rare autoimmune blistering diseases traditionally treated with systemic corticosteroids, immunosuppressants, intravenous immunoglobulins, and rituximab. Nonetheless, a subset of patients remains refractory or has contraindications to these conventional therapies.
José Javier Mateos Rico, Marta Gutiérrez Pascual, María Dolores Caro Gutiérrez, Cristina Marcos Rodríguez, Javier de Quadros Malagón, Francisco Javier Vicente Martín   +5 more
wiley   +1 more source

Case Report: Autoimmune Pemphigus Vulgaris in a Patient Treated With Cemiplimab for Multiple Locally Advanced Cutaneous Squamous Cell Carcinoma

Frontiers in Oncology, 2021
BackgroundPemphigus vulgaris (PV) is a rare and severe autoimmune blistering disorder affecting the skin and mucous membranes, characterized by the production of autoantibodies against two desmosomal adhesion proteins, desmoglein 1 and 3.
Rosalba Buquicchio, Valentina Mastrandrea, Sabino Strippoli, Davide Quaresmini, Michele Guida, Raffaele Filotico   +5 more
doaj   +1 more source

A global perspective of arrhythmogenic right ventricular cardiomyopathy. [PDF]

, 2012
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a progressive inherited heart disease characterized by ventricular arrhythmias and sudden cardiac death especially in the young. ARVC has been traditionally associated with the Mediterranean basin,
Alhashemi, M, Elmaghawry, M, Yacoub, MH, Zorzi, A   +3 more
core   +1 more source

Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle, Claire Abasq‐Thomas, Claire Bocciarelli, Amélie Bourhis, Marina Alexandre, Belen Eguia, Laurent Misery, Numa Deydier   +7 more
wiley   +1 more source