Results 101 to 110 of about 16,279,763 (246)
Gluten‐related skin disorders: clinical presentation, diagnostic and treatments
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 7, Page 857-867, July 2025.Summary Gluten‐related disorders (GRDs) encompass a spectrum of clinical manifestations triggered by gluten ingestion in genetically susceptible individuals. These disorders include celiac disease (CD) and non‐celiac gluten sensitivity (NCGS) and present with both intestinal and extraintestinal symptoms, including skin manifestations.
Dario Didona +2 more
wiley +1 more source
Glutenbedingte Hauterkrankungen: Klinik, Diagnostik und Therapie
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 7, Page 857-868, July 2025.Zusammenfassung Glutenbedingte Erkrankungen stellen ein Spektrum verschiedener klinischer Erscheinungsformen dar, die durch die Aufnahme von Gluten bei genetisch anfälligen Personen ausgelöst werden. Zu den glutenbedingten Erkrankungen gehören die Zöliakie und die Nicht‐Zöliakie‐Glutensensitivität (NCGS). Glutenbedingte Erkrankungen zeichnen sich durch
Dario Didona +2 more
wiley +1 more source
The mapping of linear B-cell epitope regions in desmoglein 1 and 3 proteins : Recognition of immobilized peptides by pemphigus patients’ serum autoantibodies [PDF]
, 2013 Desmosomal transmembrane glycoproteins desmoglein 1and desmoglein 3 are targets of life-threatening autoimmune blistering disorders such as Pemphigus vulgaris (PV) and Pemphigus foliaceus(PF).
Bősze, Szilvia +5 more
core +1 more source
Pathological IgE Production in Inborn Errors of Immunity and Beyond
Immunological Reviews, Volume 332, Issue 1, July 2025.ABSTRACT In this review, we examine different mechanisms for the generation of pathological IgE through the study of inborn errors of immunity (IEI). In particular, we focus on IEIs that are susceptible to atopic disease, such as severe eczema, eosinophilia, and/or food anaphylaxis; this group of approximately 50 genes has been coined primary atopic ...
Cindy S. Ma, Peter S. Hsu
wiley +1 more source
Topographical variations in the skin barrier and their role in disease pathogenesis
Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 7, Page 1228-1238, July 2025.Unlike the gut, the skin appears uniform at first glance. However, histological and molecular biological research has revealed significant regional variations in the composition and function of its main barrier elements. In this review, we describe the topographical differences of four barrier elements in healthy skin: microbiome, chemical, physical ...
Z. Dajnoki +5 more
wiley +1 more source
A role for caveolin-1 in desmoglein binding and desmosome dynamics. [PDF]
, 2011 Desmoglein-2 (Dsg2) is a desmosomal cadherin that is aberrantly expressed in human skin carcinomas. In addition to its well-known role in mediating intercellular desmosomal adhesion, Dsg2 regulates mitogenic signaling that may promote cancer development ...
Brennan, D +7 more
core +2 more sources
Iranian Journal of Allergy, Asthma and Immunology, 2009 Anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. Our objective was to assess the value of ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris.
Mortazavi Hossein +8 more
doaj
Apoptotic pathways in the pathogenesis of pemphigus: targets for new therapies [PDF]
, 2012 Pemphigus is a group of rare autoimmune blistering diseases of the skin in which autoantibodies to desmosome cadherins, desmogleins, induce loss of cell-cell adhesion (acantholysis).
Lotti, Roberta +2 more
core +1 more source
Frontiers in Immunology, 2019 Pemphigus vulgaris (PV) is a rare blistering disease caused by IgG autoantibodies against the epidermal adhesion molecules desmoglein (Dsg)3 and Dsg1 providing a well-characterized paradigm of an antibody-mediated organ-specific autoimmune disease. In PV
Robert Pollmann +6 more
doaj +1 more source
Engineered Tissue Models to Decode Host–Microbiota Interactions
Advanced Science, Volume 12, Issue 23, June 20, 2025.Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio +5 more
wiley +1 more source