Bullous Wells’ syndrome successfully treated with omalizumab
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Giulia Ciccarese +7 more
wiley +1 more source
Epiglottic Ulceration as an Initial Manifestation of Crohn's Disease
Journal of General and Family Medicine, Volume 27, Issue 1, January 2026.ABSTRACT Crohn's disease can present with various extraintestinal symptoms; however, laryngeal involvement, particularly epiglottic ulcers, is rare. A 52‐year‐old man presented with a sore throat. Laryngeal endoscopy revealed an epiglottic ulcer. He had no gastrointestinal symptoms.
Niina Yamashita +2 more
wiley +1 more source
Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus
Nature CommunicationsCell-cell junctions, and specifically desmosomes, are crucial for robust intercellular adhesion. Desmosomal function is compromised in the autoimmune blistering skin disease pemphigus vulgaris.
Henriette Franz +13 more
doaj +1 more source
Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells [PDF]
, 2014 Proteins of the striatin family (striatins 1–4; sizes ranging from 90 to 110 kDa on SDS-polyacrylamide gel electrophoresis) are highly homologous in their amino acid sequences but can differ in their cell-type-specific gene expression patterns and ...
Dörflinger, Yvette +7 more
core +2 more sources
Recent Progress in Double Filtration Plasmapheresis
Hemodialysis International, Volume 30, Issue 1, Page 18-25, January 2026.ABSTRACT Double‐filtration plasmapheresis is an advanced extracorporeal blood purification technique that selectively removes pathogenic macromolecules based on molecular weight. Unlike conventional plasma exchange, double‐filtration plasmapheresis uses a two‐step filtration process to retain beneficial plasma components such as albumin, while ...
Dan Li +3 more
wiley +1 more source
Journal of Clinical and Translational Science, 2017 OBJECTIVES/SPECIFIC AIMS: Pemphigus vulgaris (PV) is a potentially fatal blistering disease caused by autoantibodies to the keratinocyte adhesion protein desmoglein 3.
Nina Ran +3 more
doaj +1 more source
Cutaneous Biology: In vivo blockade of pemphigus vulgaris acantholysis by inhibition of intracellular signal transduction cascades [PDF]
, 2004 Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3.
Diaz, L.A. (L. A.) +6 more
core +1 more source
AIRE's Complex Role Beyond Promiscuous Gene Expression
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT Central tolerance, established in the thymus, ensures T cells are nonreactive to self‐antigens while maintaining a functional immune repertoire. Medullary thymic epithelial cells (mTECs) and thymic dendritic cells (DCs) play a crucial role in this mechanism by orchestrating the selection and deletion of autoreactive thymocytes, a process ...
Pärt Peterson
wiley +1 more source
The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent [PDF]
, 2017 Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional complexes. In the present study,
Acharya, Kalpana D +12 more
core +3 more sources
Sita‐ and saxagliptin use and autoantibodies to autoimmune bullous diseases: A cross‐sectional study
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Sören Dräger +8 more
wiley +1 more source