Results 111 to 120 of about 13,115 (209)
ABSTRACT Background Desquamative gingivitis is a clinical condition characterized by erythema, blisters, and erosions within the gingiva. It may be a manifestation of oral lichen planus or autoimmune bullous diseases, such as pemphigus vulgaris and mucous membrane pemphigoid. The identification of the cause of desquamative gingivitis typically involves
Urszula Fałkowska +7 more
wiley +1 more source
Chimeric Antigen Receptor T‐Cell Therapy: More Than an Anti‐Cancer Drug
ABSTRACT Initially, chimeric antigen receptor (CAR) T‐cell therapy was developed to eliminate malignant B cells in haematological B‐cell malignancies by targeting CD19 and B‐cell maturation antigen. This approach achieved notable success, resulting in (malignant) B‐cell depletion and inducing clinical remission in cancer patients.
Hannah C. M. Schenk +8 more
wiley +1 more source
JAK Inhibitors as a Novel Approach to Autoimmune Bullous Diseases: A Review
Autoimmune bullous diseases (AIBDs) are a group of chronic disorders characterized by blister formation resulting from abnormal immune responses. Janus kinase (JAK) inhibitors have emerged as promising therapeutic agents for AIBDs. This review discusses the use of JAK inhibitors—such as upadacitinib, baricitinib, tofacitinib, and abrocitinib, among ...
Olga Olisova +9 more
wiley +1 more source
T Cell Recognition of Desmoglein 3 Peptides in Patients with Pemphigus Vulgaris and Healthy Individuals [PDF]
Christian Veldman +6 more
openalex +1 more source
Background Walking along disease-associated protein sequences in the search for specific segments able to induce cellular immune response may direct clinical research towards effective peptide-based vaccines.
Kanduc Darja +4 more
doaj +1 more source
Protection against Pemphigus Foliaceus by Desmoglein 3 in Neonates [PDF]
Hong Wu +10 more
openalex +1 more source
New insights into desmosome regulation and pemphigus blistering as a desmosome-remodeling disease
Desmosomes in keratinocytes are the most important intercellular adhering junctions that provide structural strength for the epidermis. These junctions are connected directly with desmosomal cadherin proteins.
Yasuo Kitajima
doaj +1 more source
T cell autoimmunity and immune regulation to desmoglein 3, a pemphigus autoantigen. [PDF]
Takahashi H, Iriki H, Asahina Y.
europepmc +1 more source
Background Various antigen-specific immunoassays are available for the serological diagnosis of autoimmune bullous diseases. However, a spectrum of different tissue-based and monovalent antigen-specific assays is required to establish the diagnosis ...
van Beek Nina +9 more
doaj +1 more source

