Results 81 to 90 of about 18,739,280 (231)

Diagnostic Utility of BIOCHIP Mosaic Indirect Immunofluorescence in Intraepidermal Autoimmune Blistering Diseases

Clinical Dermatology Review
Background: Pemphigus is a chronic intraepidermal autoimmune blistering disorder (IABD) characterized by the presence of circulating autoantibodies against desmogleins 1and 3.
Padmini Chitradurga Vijayasarathy, Rajalakshmi Tirumalae   +1 more
doaj   +1 more source

Isolated perineal plaque as the initial presentation of pemphigus vulgaris [PDF]

JAAD Case Reports
Aster Workineh, MPH, Gauri Panse, MD, Mary Tomayko, MD, PhD, Alicia J. Little, MD, PhD   +3 more
doaj   +2 more sources

Desmoglein 3 gene mediates epidermal growth factor/epidermal growth factor receptor signaling pathway involved in inflammatory response and immune function of anaphylactic rhinitis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
OBJECTIVE To investigate the effects of desmoglein 3 (DSG3) gene mediating epidermal growth factor/epidermal growth factor receptor (EGF/EGFR) signaling pathway on inflammatory response and immune function of anaphylactic rhinitis (AR).
H. Ri, Zheng Peiyan, Wang Jianqi, Zhao Yunteng, Li Gang, S. Baoqing   +5 more
semanticscholar   +1 more source

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

International Journal of Dermatology, EarlyView.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes, Negar Esfandiari, Steven Daveluy   +2 more
wiley   +1 more source

LB1800 TWEAK-induced apoptosis depletes desmoglein 1 and 3 via STAT1 in pemphigus [PDF]

, 2023
Yujing Liu, Peng Xia, Yuan Xia
openalex   +1 more source

Proteomic definition of a desmoglein linear determinant common to Pemphigus vulgaris and Pemphigus foliaceous

Journal of Translational Medicine, 2006
Background A number of autoimmune diseases have been clinically and pathologically characterized. In contrast, target antigens have been identified only in a few cases and, in these few cases, the knowledge of the exact epitopic antigenic sequence is ...
Sinha Animesh A, Serpico Rosario, Tessitore Luciana, Mittelman Abraham, Lucchese Alberta, Kanduc Darja   +5 more
doaj   +1 more source

Desmoglein-3 acts as a pro-survival protein by suppressing reactive oxygen species and doming whilst augmenting the tight junctions in MDCK cells.

Mechanisms of Ageing and Development, 2019
Kidney disease prevalence increases with age, with a common feature of the disease being defects in the epithelial tight junctions. Emerging evidence suggests that the desmosomal adhesion protein Desmoglein-3 (Dsg3) functions beyond the desmosomal ...
Xiao Li, U. Ahmad, Yunying Huang, Jutamas Uttagomol, A. Rehman, Ke-yan Zhou, G. Warnes, S. McArthur, E. K. Parkinson, Hong Wan   +9 more
semanticscholar   +1 more source

Evidence for Dsg3 in regulating Src signaling by competing with it for binding to caveolin-1

Data in Brief, 2016
This data article contains extended, complementary analysis related to the research articles entitled “Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src” (Tsang et al., 2010) [1] and figures related to the review ...
Hong Wan, Kuang Lin, Siu Man Tsang, Jutamas Uttagomol   +3 more
doaj   +1 more source

Pathogenic monoclonal antibody against desmoglein 3 augments desmoglein 3 and p38 MAPK phosphorylation in human squamous carcinoma cell line

Autoimmunity, 2006
Pemphigus vulgaris is an autoimmune blistering disease characterized by cell-cell detachment of epidermal cells. Autoantibody against desmoglein (Dsg) 3, a transmembrane glycoprotein that mediates the association of desmosomes, plays a major role in blistering in pemphigus vulgaris (PV). The mechanisms of autoantibody-induced acantholysis have not been
Yuki, Kawasaki, Yumi, Aoyama, Kazuyuki, Tsunoda, Masayuki, Amagai, Yasuo, Kitajima   +4 more
openaire   +2 more sources

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source