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Desmosomes in Human Disease

Annual Review of Pathology: Mechanisms of Disease, 2018
Tissue integrity is crucial for maintaining the homeostasis of living organisms. Abnormalities that affect sites of cell-cell contact can cause a variety of debilitating disorders. The desmosome is an essential cell-cell junctional protein complex in tissues that undergo stress, and it orchestrates intracellular signal transduction. Desmosome assembly
openaire   +2 more sources

Desmosomes and their autoimmune pathologies.

European journal of dermatology : EJD, 2000
Desmosomes guarantee the integrity of the epidermis, by functioning both as an adhesive complex and as a cell-surface attachment site for the keratin intermediate filaments of the cytoskeleton. Considerable progress has been made in our knowledge of desmosomes and their components.
COZZANI, EMANUELE CLAUDIO   +4 more
openaire   +2 more sources

miR-195-5p as Regulator of γ-Catenin and Desmosome Junctions in Colorectal Cancer

International Journal of Molecular Sciences, 2023
Emanuele Piccinno   +2 more
exaly  

Comprehensive Desmosome Mutation Analysis in North Americans With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

Circulation: Cardiovascular Genetics, 2009
Laura Ibanez Lladó   +2 more
exaly  

Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography

Proceedings of the National Academy of Sciences of the United States of America, 2020
Mateusz Sikora   +2 more
exaly  

Plakoglobin localization to the cell border restores desmosome function in cells lacking 14-3-3γ

Biochemical and Biophysical Research Communications, 2018
Sarika Tilwani, Sorab N Dalal
exaly  

Peroxisome-desmosome complexes in mouse hepatic cells

Zeitschrift Für Zellforschung Und Mikroskopische Anatomie, 1970
Bernard Tandler   +2 more
exaly  

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