Results 11 to 20 of about 13,508 (185)
Hypothesis: Ephrin-Eph Signaling Pathways Provide Novel Targets for Accelerated Re-Epithelialization of Cutaneous Wounds. [PDF]
BioessaysIn distal limb wounds on the horse, the proliferative phase of repair often produces excessive granulation tissue that delays healing by impeding keratinocyte migration from wound margins. This essay examines the basis for the hypothesis that ephrin–Eph signaling pathways that stimulate keratinocyte migration provide novel targets for re‐establishing ...
Vicetti Miguel RD +3 more
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The tandem-random transition of cellular patterning: proposed roles of N-cadherin-based orientational cell adhesions in the development, maintenance, and degeneration of the nucleus pulposus. [PDF]
Biol Rev Camb Philos SocABSTRACT Intervertebral disc degeneration (IDD) can contribute to lower back and neck pain. In IDD, the most affected component of the intervertebral disc is the nucleus pulposus (NP). Derived from the notochord, where cells are organized into a tandem configuration, young NP cells cluster in three‐dimensional (3D) networks embedded in a gelatinous ...
Wei X, Vo N, Sowa GA.
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Vaccines, 2022 Pemphigus vulgaris (PV) is a chronic, life-altering autoimmune disease due to the production of anti-desmoglein antibodies causing the loss of cell–cell adhesion in keratinocytes (acantholysis) and blister formation in both skin and mucous membranes. The
Morna F. Schmidt +4 more
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Paradoxical Roles of Desmosomal Components in Head and Neck Cancer
Biomolecules, 2021 Desmosomes are intercellular adhesion complexes involved in various aspects of epithelial pathophysiology, including tissue homeostasis, morphogenesis, and disease development.
Yin-Qiao Liu +3 more
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Cheek-Pro-Heart: What Can the Buccal Mucosa Do for Arrhythmogenic Cardiomyopathy?
Biomedicines, 2023 Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease associated with ventricular arrhythmias and a high risk of sudden cardiac death (SCD). Although the disease was described over 40 years ago, its diagnosis is still difficult.
Carlos Bueno-Beti, Angeliki Asimaki
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Biology, 2020 Tumor resistance to therapy is associated with the 3D organization and peculiarities of the tumor microenvironment, of which intercellular adhesion is a key participant. In this work, the abundance of contact proteins was compared in SKOV-3 and SKOV-3.ip
Olga M. Kutova +6 more
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Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum
Dermatologica Sinica, 2015 Desmosomes and corneodesmosomes are the most important adhering junctions, providing strength for the epidermal sheet structure made of living keratinocytes and enucleated stratum corneum corneocytes, respectively.
Yasuo Kitajima
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Genetic Animal Models for Arrhythmogenic Cardiomyopathy
Frontiers in Physiology, 2020 Arrhythmogenic cardiomyopathy has been clinically defined since the 1980s and causes right or biventricular cardiomyopathy associated with ventricular arrhythmia.
Brenda Gerull +2 more
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Histopathological Features and Protein Markers of Arrhythmogenic Cardiomyopathy
Frontiers in Cardiovascular Medicine, 2021 Arrhythmogenic cardiomyopathy (ACM) is a heritable heart muscle disease characterized by syncope, palpitations, ventricular arrhythmias and sudden cardiac death (SCD) especially in young individuals.
Carlos Bueno-Beti, Angeliki Asimaki
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Cells, 2018 Cell-cell junctions are critical structures in a number of tissues for mechanically coupling cells together, cell-to-cell signaling, and establishing a barrier. In many tissues, desmosomes are an important component of cell-cell junctions.
Sindora R. Baddam +9 more
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