Results 31 to 40 of about 12,732 (174)
Messages from Mutant Desmosomes [PDF]
Journal of Investigative Dermatology, 2022 Single gene disorders are ideally suited to establish robust genotype‒phenotype correlations and provide excellent opportunities to understand molecular pathomechanisms with relevance to complex disorders. The observation that patients diagnosed with the same causative mutation can present with phenotypic disease variability illustrates the significant
Thomas M. Magin, Mechthild Hatzfeld
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Role of PKC and ERK Signaling in Epidermal Blistering and Desmosome Regulation in Pemphigus
Frontiers in Immunology, 2019 Desmosomes reinforce cohesion of epithelial cells at the interface between adjacent cells. They include the cadherin-type adhesion molecules desmoglein 1 (Dsg1) and Dsg3.
Desalegn Tadesse Egu +2 more
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Cheek-Pro-Heart: What Can the Buccal Mucosa Do for Arrhythmogenic Cardiomyopathy?
Biomedicines, 2023 Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease associated with ventricular arrhythmias and a high risk of sudden cardiac death (SCD). Although the disease was described over 40 years ago, its diagnosis is still difficult.
Carlos Bueno-Beti, Angeliki Asimaki
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Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes [PDF]
Journal of Cell Biology, 2011 The desmosomal cadherins, desmogleins (Dsgs) and desmocollins (Dscs), comprise the adhesive core of intercellular junctions known as desmosomes. Although these adhesion molecules are known to be critical for tissue integrity, mechanisms that coordinate their trafficking into intercellular junctions to regulate their proper ratio and distribution are ...
Nekrasova, Oxana E. +5 more
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The Journal of Cell Biology, 1970 During the pupal stage of moths, a mass of connective tissue develops on the dorsal side of the abdominal nerve cord . The cells, which secrete the fibrous matrix, are originally close together, but as they secrete the matrix, they are pushed apart, with a corresponding decrease in their size .
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Assembly of Desmosomal Cadherins into Desmosomes is Isoform Dependent [PDF]
Journal of Investigative Dermatology, 2001 Desmosomes are intercellular adhesive junctions that exhibit cell- and differentiation-specific differences in their molecular composition. In complex epithelia, desmosomes contain multiple representatives of the desmosomal cadherin family, which includes three desmogleins and three desmocollins.
Ishii, Ken +5 more
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Frontiers in Immunology, 2018 The serological diagnosis of pemphigus relies on the detection of IgG autoantibodies directed against the epithelial cell surface by indirect immunofluorescence (IIF) on monkey esophagus and against desmoglein 1 (Dsg1) and Dsg3 by ELISA.
Federica Giurdanella +4 more
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Histopathological Features and Protein Markers of Arrhythmogenic Cardiomyopathy
Frontiers in Cardiovascular Medicine, 2021 Arrhythmogenic cardiomyopathy (ACM) is a heritable heart muscle disease characterized by syncope, palpitations, ventricular arrhythmias and sudden cardiac death (SCD) especially in young individuals.
Carlos Bueno-Beti, Angeliki Asimaki
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Expression of desmosomal proteins and their implications during enamel organ morphogenesis
Indian Journal of Dental Sciences, 2018 Background/Objective: The present article is between the fewest that describe the expression of desmosomal proteins in human tooth organ and to implicate desmosome and its components in tooth morphogenesis.
Hadi BILAL
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Advanced Science, EarlyView.This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu +9 more
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