Results 31 to 40 of about 20,510 (243)
Cells, 2023 The role of desmoglein-3 (DSG3) in oncogenesis is unclear. This study aimed to uncover molecular mechanisms through comparative transcriptome analysis in oral cancer cells, defining potential key genes and associated biological processes related to DSG3 ...
Hong Wan +3 more
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Cells, 2018 Cell-cell junctions are critical structures in a number of tissues for mechanically coupling cells together, cell-to-cell signaling, and establishing a barrier. In many tissues, desmosomes are an important component of cell-cell junctions.
Sindora R. Baddam +9 more
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Desmosomes and sino-atrial dysfunction [PDF]
Cardiovascular Research, 2016 This editorial refers to ‘Desmosomal junctions are necessary for adult sinus node function’ by V. Mezzano et al. , doi:10.1093/cvr/cvw083. Heart automaticity is a fundamental physiological function, yet it remains still incompletely understood, probably because of its intrinsic complexity at both cellular and tissue levels.
Matteo E. Mangoni
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Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum
Dermatologica Sinica, 2015 Desmosomes and corneodesmosomes are the most important adhering junctions, providing strength for the epidermal sheet structure made of living keratinocytes and enucleated stratum corneum corneocytes, respectively.
Yasuo Kitajima
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Vaccines, 2022 Pemphigus vulgaris (PV) is a chronic, life-altering autoimmune disease due to the production of anti-desmoglein antibodies causing the loss of cell–cell adhesion in keratinocytes (acantholysis) and blister formation in both skin and mucous membranes. The
Morna F. Schmidt +4 more
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Pervanadate stabilizes desmosomes [PDF]
Cell Adhesion & Migration, 2008 Desmosomes are intercellular junctions responsible for strong cell-cell adhesion in epithelia and cardiac muscle. Numerous studies have shown that the other major type of epithelial cell adhesion, the adherens junction, is destabilized by src-induced tyrosine phosphorylation of two of its principal components, E-cadherin and beta-catenin.
Garrod, D. +3 more
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Российский кардиологический журнал, 2021 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a hereditary myocardial disease with a high risk of sudden cardiac death. The most common genetic forms of the disease are associated with desmosomal gene mutations.Aim. To study the prevalence of
A. G. Shestak +4 more
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Cold Spring Harbor Perspectives in Biology, 2018 Cadherin-based adherens junctions (AJs) and desmosomes are crucial to couple intercellular adhesion to the actin or intermediate filament cytoskeletons, respectively.
M. Rübsam +5 more
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The Journal of Cell Biology, 1970 During the pupal stage of moths, a mass of connective tissue develops on the dorsal side of the abdominal nerve cord . The cells, which secrete the fibrous matrix, are originally close together, but as they secrete the matrix, they are pushed apart, with a corresponding decrease in their size .
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Role of PKC and ERK Signaling in Epidermal Blistering and Desmosome Regulation in Pemphigus
Frontiers in Immunology, 2019 Desmosomes reinforce cohesion of epithelial cells at the interface between adjacent cells. They include the cadherin-type adhesion molecules desmoglein 1 (Dsg1) and Dsg3.
Desalegn Tadesse Egu +2 more
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