Results 21 to 30 of about 25,080 (259)

Effects of Maternal Exposure to Decamethylcyclopentasiloxane on the Alternations in Offspring Behaviors in Mice

Biomedicines, 2022
D5, a member of the cyclic siloxane family, is widely used in personal care products such as shampoo, cosmetics, and deodorant and as an industrial intermediate. D5 can mainly be absorbed orally or through inhalation.
Donglin Yi, Kangmin Kim, Minsu Lee, Eui-man Jung, Eui-Bae Jeung   +4 more
doaj   +1 more source

Histo-anatomical mutilations of developing chick brain induced by in-ovo fluoride and bifenthrin exposure

Toxicology Reports, 2023
Comparative developing brain histo-anatomical pathologies of Fluoride ions and Bifenthrin in-ovo exposures were explored in the golden black variety of domestic chick. Three exposure groups were –the Vehicle control group (Vg); Fluoride (F) group and the
Ayesha Faisal, Zubedah Khanum, Syeda Nadia Ahmad, Khawaja Raees Ahmad, Asma Younis, Sadia Suleman, Iram Inayat, Muhammad Ali Kanwal   +7 more
doaj   +1 more source

Neurogenesis and developmental anesthetic neurotoxicity [PDF]

Neurotoxicology and Teratology, 2017
The mechanism by which anesthetics might act on the developing brain in order to cause long term deficits remains incompletely understood. The hippocampus has been identified as a structure that is likely to be involved, as rodent models show numerous deficits in behavioral tasks of learning that are hippocampal-dependent. The hippocampus is an unusual
Eunchai, Kang, Daniel A, Berg, Orion, Furmanski, William M, Jackson, Yun Kyoung, Ryu, Christy D, Gray, C David, Mintz   +6 more
openaire   +2 more sources

Differentiated Neurons Are More Vulnerable to Organophosphate and Carbamate Neurotoxicity than Undifferentiated Neurons Due to the Induction of Redox Stress and Accumulate Oxidatively-Damaged Proteins

Brain Sciences, 2023
Organophosphate (OP) and carbamate pesticides are toxic to pests through targeted inhibition of acetylcholinesterase (AChE). However, OPs and carbamates may be harmful to non-target species including humans and could induce developmental neurotoxicity if
Anusha W. Mudyanselage, Buddhika C. Wijamunige, Artur Kocon, Wayne G. Carter   +3 more
doaj   +1 more source

Differences in neurotoxic outcomes of organophosphorus pesticides revealed via multi-dimensional screening in adult and regenerating planarians

Frontiers in Toxicology, 2022
Organophosphorus pesticides (OPs) are a chemically diverse class of commonly used insecticides. Epidemiological studies suggest that low dose chronic prenatal and infant exposures can lead to life-long neurological damage and behavioral disorders.
Danielle Ireland, Siqi Zhang, Veronica Bochenek, Jui-Hua Hsieh, Christina Rabeler, Zane Meyer, Zane Meyer, Eva-Maria S. Collins, Eva-Maria S. Collins, Eva-Maria S. Collins, Eva-Maria S. Collins, Eva-Maria S. Collins   +11 more
doaj   +1 more source

Clearing the Air on Pollutant Disruptions of the Gut–Brain Axis: Developmental Exposure to Benzo[a]pyrene Disturbs Zebrafish Behavior and the Gut Microbiome in Adults and Subsequent Generations

Toxics
Developmental exposure to benzo[a]pyrene (BaP), a ubiquitous environmental pollutant, has been linked to various toxic effects, including multigenerational behavioral impairment.
Alexandra Alexiev, Ebony Stretch, Kristin D. Kasschau, Lindsay B. Wilson, Lisa Truong, Robyn L. Tanguay, Thomas J. Sharpton   +6 more
doaj   +1 more source

Curcumin protects against fenvalerate-induced neurotoxicity in zebrafish (Danio rerio) larvae through inhibition of oxidative stress

Ecotoxicology and Environmental Safety, 2023
Fenvalerate (FEN), a typical type II pyrethroid pesticide, is widely used in agriculture. FEN has been detected in the environment and human body. However, the neurotoxicity of FEN has not been well elucidated.
Jiansheng Zhu, Mingtao Huang, Chunlan Liu, Jingyu Wang, Li Zou, Fan Yang, Renfei Zhu   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact of environmental neurotoxic: current methods and usefulness of human stem cells

Heliyon, 2020
The development of central nervous system is a highly coordinated and complex process. Any alteration of this process can lead to disturbances in the structure and function of the brain, which can cause deficits in neurological development, resulting in ...
Andreea Rosca, Raquel Coronel, Miryam Moreno, Rosa González, Andreea Oniga, Alberto Martín, Victoria López, María del Carmen González, Isabel Liste   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source