Results 11 to 20 of about 98,007 (275)

Dextran sodium sulfate (DSS) induces colitis in mice by forming nano-lipocomplexes with medium-chain-length fatty acids in the colon. [PDF]

PLoS ONE, 2012
Inflammatory bowel diseases (IBDs), primarily ulcerative colitis and Crohn's disease, are inflammatory disorders caused by multiple factors. Research on IBD has often used the dextran sodium sulfate (DSS)-induced colitis mouse model.
Hamed Laroui, Sarah A Ingersoll, Hong Chun Liu, Mark T Baker, Saravanan Ayyadurai, Moiz A Charania, Famina Laroui, Yutao Yan, Shanthi V Sitaraman, Didier Merlin   +9 more
doaj   +1 more source

Alloferon Alleviates Dextran Sulfate Sodium-induced Colitis [PDF]

Immune Network, 2015
Dysfunction of gut immune regulation is involved in mucosal damage in inflammatory bowel disease (IBD). However, there is still no efficacious immune-regulator for the treatment of IBD. Alloferon is a novel immune-modulatory peptide that was originally isolated from infected insects.
Kim, Hyemin, Im, Jong Pil, Kim, Joo Sung, Kang, Jae Seung, Lee, Wang Jae   +4 more
openaire   +2 more sources

Dextran Sulfate Sodium (DSS)‐Induced Colitis in Mice [PDF]

Current Protocols in Immunology, 2014
AbstractInflammatory bowel diseases (IBD), mainly comprising ulcerative colitis and Crohn's Disease, are complex and multifactorial diseases with unknown etiology. For the past 20 years, to study human IBD mechanistically, a number of murine models of colitis have been developed. These models are indispensable tools to decipher underlying mechanisms of
Benoit, Chassaing, Jesse D, Aitken, Madhu, Malleshappa, Matam, Vijay-Kumar   +3 more
openaire   +2 more sources

Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. [PDF]

, 2020
Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium ...
Farzaneh, Ted, Ichii, Hirohito, Lau, Hien, Li, Shiri, Robles, Lourdes, Stamos, Michael J, Takasu, Chie, Vaziri, Nosratola D, Vo, Kelly   +8 more
core   +2 more sources

Murine Colitis Modeling using Dextran Sulfate Sodium (DSS) [PDF]

Journal of Visualized Experiments, 2010
Colitis can occur from viral or bacterial infections, ischemic insult, or autoimmune disorders; most notably Ulcerative Colitis and the colonic variant of Crohn's Disease - Crohn's Colitis. Acute colitis may present with abdominal pain and distention, malabsorption, diarrhea, hematochezia and mucus in the stool.
Whittem, Caitlyn G., Williams, Amanda D., Williams, Christopher S.   +2 more
openaire   +2 more sources

CU06-1004 Alleviates Experimental Colitis by Modulating Colonic Vessel Dysfunction

Frontiers in Pharmacology, 2020
Inflammatory bowel disease is an autoimmune disease that causes chronic inflammation of the gastrointestinal tract. Endothelial dysfunction, defined by a reduced endothelial barrier and an increase in the expression of adhesion molecules, is part of the ...
Ye-Seul Kim, Haiying Zhang, Sunghye Lee, Songyi Park, Minyoung Noh, Young-Myeong Kim, Young-Guen Kwon   +6 more
doaj   +1 more source

Minimally invasive in vivo endoscopic monitoring of dextran sulfate sodium-induced murine colitis

MethodsX, 2022
Ulcerative colitis (UC) is a gastrointestinal, autoimmune disease that causes ulceration and inflammation of the colon with an incidence of 10 out of every 100,000 people in North America and Western Europe.
Elizabeth A. Bullard, Ariel I. Mundo, Shelby N. Bess, Kathryn Miller Priest, Timothy J. Muldoon   +4 more
doaj   +1 more source

Dextran Sulfate Sodium Salt-Induced Colitis Aggravates Gut Microbiota Dysbiosis and Liver Injury in Mice With Non-alcoholic Steatohepatitis

Frontiers in Microbiology, 2021
Objective: Inflammatory bowel disease (IBD) is characterized by gut microbiota dysbiosis, which is also frequently observed in patients with non-alcoholic fatty liver disease.
Bo Shen, Bo Shen, Junjun Wang, Junjun Wang, Yuecheng Guo, Yuecheng Guo, Tianyi Gu, Tianyi Gu, Zhenyang Shen, Zhenyang Shen, Cui Zhou, Cui Zhou, Binghang Li, Binghang Li, Xianjun Xu, Xianjun Xu, Fei Li, Fei Li, Qidi Zhang, Qidi Zhang, Xiaobo Cai, Xiaobo Cai, Hui Dong, Hui Dong, Lungen Lu, Lungen Lu   +25 more
doaj   +1 more source

Melatonin Attenuates Dextran Sodium Sulfate Induced Colitis in Obese Mice

Pharmaceuticals, 2021
Epidemiological studies have indicated that obesity is an independent risk factor for colitis and that a high-fat diet (HFD) increases the deterioration of colitis-related indicators in mice.
Shijia Pan, Fan Hong, Letong Li, Yuan Guo, Xiaoxiao Qiao, Jia Zhang, Pengfei Xu, Yonggong Zhai   +7 more
doaj   +1 more source

Anti-inflammation and gut microbiota regulation properties of fatty acids derived from fermented milk in mice with dextran sulfate sodium-induced colitis

Journal of Dairy Science, 2022
: The by-products of milk fermentation by lactic acid bacteria provide potential health benefits to the balance of host intestinal microflora. In this study, the anti-inflammatory properties of fatty acids from monoculture-strain (Lactiplantibacillus ...
Lifeng Lao, Guo Yang, Ao Zhang, Lianliang Liu, Yuxing Guo, Liwei Lian, Daodong Pan, Zhen Wu   +7 more
doaj   +1 more source