Results 91 to 100 of about 2,373 (170)

Polyamine-dependent metabolic shielding regulates alternative splicing. [PDF]

Nature
Zabala-Letona A, Pujana-Vaquerizo M, Martinez-Laosa B, Ponce-Rodriguez M, Garcia-Longarte S, Mendizabal I, Gimeno A, Rogalska M, Tan J, Cabrera D, van Liempd S, Ximenez-Embun P, Espinosa S, Fagoaga-Eugui M, Peccati F, Zakrzewski M, Astobiza I, Arana-Castañares M, Cherkaoui S, Sendino M, Martín-Barros I, Ercilla A, Bozal-Basterra L, Carlevaris O, Arruabarrena-Aristorena A, Pérez-Andrés E, Santamaría-Zamorano T, Ferrer-Bonsoms JA, Carazo F, Cieśla M, Lobato C, Seoane J, Martín-Martín N, Barrio R, Sutherland JD, Aransay AM, Falcón-Pérez JM, Martínez-Pastor B, Rubio A, Blanco FJ, Hogarty MD, Morscher RJ, Berra E, Serwa RA, Jiménez-Barbero J, Jiménez-Osés G, Efeyan A, Finley L, Lizcano JM, Muñoz J, Valcarcel J, Carracedo A.   +51 more
europepmc   +1 more source

QW-5-70 targets the colchicine site and demonstrates antitumor activity in P-gp-overexpressing cancer models. [PDF]

Mol Cancer Ther
Xie Y, Hou R, Albadari N, Chen H, Miller DJ, Quadrozzi Gruntz J, Oldham ML, Kamal MS, Jiang J, Wu Z, Miller DD, Li W.   +11 more
europepmc   +1 more source

Combined inhibition of polyamine biosynthesis and uptake blocks <i>Candida albicans</i> virulence. [PDF]

mBio
Vindu A, Snarr BD, Cao C, Rolfes RJ, Phanstiel O, Lionakis MS, Dever TE.   +6 more
europepmc   +1 more source

Polyamine metabolism in cancer: drivers of immune evasion, ferroptosis and therapy resistance. [PDF]

Expert Rev Mol Med
Chenna SS, Gajula SNR, Nalla LV.
europepmc   +1 more source

Opposite effects of spermidine and GC7 in cell culture are dictated by distinct molecular targets. [PDF]

Biochem J
Tahara T, Bordone R, Campese AF, Cantale Aeo NM, Astolfi R, Coni S, Ragno R, Canettieri G, Agostinelli E.   +8 more
europepmc   +1 more source

Reprogramming neuroblastoma by diet-enhanced polyamine depletion. [PDF]

Nature
Cherkaoui S, Turn CS, Yuan Y, Lu W, Yang L, McBride MJ, Eigenmann C, Allen GE, Panasenko OO, Zhang L, Vu A, Liu K, Li Y, Gandhi OH, Surrey LF, Kienast SD, Leidel SA, Wierer M, White E, Rabinowitz JD, Hogarty MD, Morscher RJ.   +21 more
europepmc   +1 more source

Phase I dose-escalation trial of AMXT 1501 dicaprate plus difluoromethylornithine: a dual-agent approach targeting immunosuppressive polyamine metabolism. [PDF]

ESMO Open
Piha-Paul SA, Tolcher AW, Vandross AL, Spira AI, Burns MR.   +4 more
europepmc   +1 more source

Eflornithine for the Chemoprevention of Luminal Gastrointestinal Neoplasms: A Systematic Review. [PDF]

Gastroenterology Res
Godoy A, Montalvan-Sanchez D, Principe-Meneses FS, Riva-Moscoso A, Sierra L, Erazo G, Avila C, Ramirez-Rojas M, Giron R, Guifarro DA.   +9 more
europepmc   +1 more source

Glycolysis maintains effector function of lung Th17 TRM cells in precision cut lung slices. [PDF]

iScience
Yang H, Kumaran VR, Song K, Remcho TP, Clark RDE, Thakur S, Lu S, Harrison MAA, Iwanaga N, Garcia-Hernandez ML, Rangel-Moreno J, Zwezdaryk KJ, McCombs JE, Norton EB, Kolls JK.   +14 more
europepmc   +1 more source

Polyamines regulate mitochondrial metabolism essential for intestinal epithelial renewal and wound healing. [PDF]

Am J Physiol Gastrointest Liver Physiol
Cairns CA, Chen T, Han N, Chen H, Chung HK, Xiao L, Wang JY.   +6 more
europepmc   +1 more source