Results 1 to 10 of about 128,436 (385)

Synaptotagmins at the endoplasmic reticulum–plasma membrane contact sites maintain diacylglycerol homeostasis during abiotic stress

The Plant Cell, 2021
Endoplasmic reticulum–plasma membrane contact sites (ER–PM CS) play fundamental roles in all eukaryotic cells. Arabidopsis thaliana mutants lacking the ER–PM protein tether synaptotagmin1 (SYT1) exhibit decreased PM integrity under multiple abiotic ...
N. Ruíz-López, Jessica Pérez-Sancho, A. E. del Valle, R. Haslam, Steffen Vanneste, R. Catalá, C. Perea-Resa, D. Damme, Selene García-Hernández, A. Albert, José G. Vallarino, Jinxing Lin, Jir□í Friml, A. Macho, J. Salinas, A. Rosado, J. Napier, V. Amorim-Silva, M. Botella   +18 more
semanticscholar   +1 more source

DIP2 is a unique regulator of diacylglycerol lipid homeostasis in eukaryotes

eLife, 2022
Chain-length-specific subsets of diacylglycerol (DAG) lipids are proposed to regulate differential physiological responses ranging from signal transduction to modulation of the membrane properties.
Sudipta Mondal, Priyadarshan Kinatukara, Shubham Singh, Sakshi Shambhavi, Gajanan S Patil, Noopur Dubey, Salam Herojeet Singh, Biswajit Pal, P Chandra Shekar, Siddhesh S Kamat, Rajan Sankaranarayanan   +10 more
doaj   +1 more source

Diacylglycerol-evoked activation of PKC and PKD isoforms in regulation of glucose and lipid metabolism: a review

Lipids in Health and Disease, 2020
Protein kinase C (PKC) and Protein kinase D (PKD) isoforms can sense diacylglycerol (DAG) generated in the different cellular compartments in various physiological processes.
Katarzyna Kolczynska, A. Loza-Valdes, Izabela Hawro, G. Sumara   +3 more
semanticscholar   +1 more source

A review of phosphatidate phosphatase assays

Journal of Lipid Research, 2020
Phosphatidate phosphatase (PAP) catalyzes the penultimate step in the synthesis of triacylglycerol and regulates the synthesis of membrane phospholipids.
Prabuddha Dey, Gil-Soo Han, George M. Carman   +2 more
doaj   +1 more source

Perilipin 3 promotes the formation of membrane domains enriched in diacylglycerol and lipid droplet biogenesis proteins

Frontiers in Cell and Developmental Biology, 2023
Lipid droplets (LDs) serve as intracellular stores of energy-rich neutral lipids. LDs form at discrete sites in the endoplasmic reticulum (ER) and they remain closely associated with the ER during lipogenic growth and lipolytic consumption.
Rasha Khaddaj, Jiri Stribny, Stéphanie Cottier, Roger Schneiter   +3 more
doaj   +1 more source

Structure and mechanism of human diacylglycerol O-acyltransferase-1

Nature, 2020
Diacylglycerol O-acyltransferase 1 (DGAT1) synthesizes triacylglycerides and is required for dietary fat absorption and fat storage in humans1. DGAT1 belongs to the membrane-bound O-acyltransferase (MBOAT) superfamily, members of which are found in all ...
Lie Wang, H. Qian, Yin Nian, Yin Nian, Yimo Han, Yimo Han, Z. Ren, Hanzhi Zhang, Liya Hu, B. Prasad, A. Laganowsky, N. Yan, Ming Zhou   +12 more
semanticscholar   +1 more source

Fermentative Production of Diacylglycerol by Endophytic Fungi Screened from Taxus chinensis var. mairei

Foods, 2023
Diacylglycerol (DAG) production by microbial fermentation has broad development prospects. In the present study, five endophytic fungi which could accumulate DAG were screened from Taxus chinensis var. mairei by using potato dextrose agar plate and flask
Wenqiang Xu, Haoran Bi, Hong Peng, Ling Yang, Hongwei He, Guiming Fu, Yuhuan Liu, Yin Wan   +7 more
doaj   +1 more source

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Every cell produces thousands of lipid species, but studying the function of individual lipids in living cells is almost impossible with existing methodologies.
Milena Schuhmacher, Andreas T. Grasskamp, Pavel Barahtjan, Nicolai Wagner, Benoit Lombardot, J. Schuhmacher, Pia Sala, Annett Lohmann, Ian Henry, A. Shevchenko, Ü. Coskun, Alexander M. Walter, André Nadler   +12 more
semanticscholar   +1 more source

Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain

BMC Neuroscience, 2008
Background Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain
Undieh Ashiwel S, Vongtau Habiba OU, Tyeryar Kimberly R   +2 more
doaj   +1 more source

Effect of Diacylglycerol Crystallization on W/O/W Emulsion Stability, Controlled Release Properties and In Vitro Digestibility

Foods, 2023
Water-in-oil-in-water (W/O/W) emulsions with high-melting diacylglycerol (DAG) crystals incorporated in the oil droplets were fabricated and the compositions were optimized to achieve the best physical stability.
Chaoying Qiu, Yingwei Liu, Canfeng Chen, Yee Ying Lee, Yong Wang   +4 more
doaj   +1 more source